Gene: Usp3

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Phenotype System Allele Zyg Sex Life Stage P Value
decreased total body fat amount Usp3tm1b(EUCOMM)Wtsi HET postnatal 7.56×10-05
decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number Usp3tm1a(EUCOMM)Wtsi HET postnatal 1.69×10-05
preweaning lethality, incomplete penetrance Usp3tm1a(EUCOMM)Wtsi HOM n/a 0.00
preweaning lethality, incomplete penetrance Usp3tm1b(EUCOMM)Wtsi HOM n/a 0.00

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (2/2)  Wholemount images
Aorta 2 No  (2/2)  Wholemount images
Bone 2 No  Wholemount images
Brain 2 No  (2/2)  Wholemount images
Brainstem 2 No  (2/2)  Wholemount images
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (2/2)  Wholemount images
Cerebellum 2 No  (2/2)  Wholemount images
Cerebral cortex 2 No  (2/2)  Wholemount images
Esophagus 2 No  (7/415)  (2/2)  Wholemount images
Eye 2 No  (2/2)  Wholemount images
Gall bladder 2 No  (2/2)  Wholemount images
Heart 2 No  (2/2)  Wholemount images
Hippocampus 2 No  (2/2)  Wholemount images
Hypothalamus 2 No  (2/2)  Wholemount images
Kidney 2 No  (18/584)  (2/2)  Wholemount images
Large intestine 2 No  (10/584)  (2/2)  Wholemount images
Liver 2 No  (2/2)  Wholemount images
Lower urinary tract 2 No  (2/2)  Wholemount images
Lung 2 No  (2/2)  Wholemount images
Lymph node 2 No  (2/2)  Wholemount images
Mammary gland 2 No  (1/2)  Wholemount images
Olfactory lobe 2 No  (2/2)  Wholemount images
Oral epithelium 2 No  (1/2)  Wholemount images
Ovary 2 No  (1/584)  (1/2)  Wholemount images
Oviduct 2 No  (1/2)  Wholemount images
Pancreas 2 No  (5/584) N/A
Parathyroid gland 2 No  (2/2)  Wholemount images
Peripheral nervous system 2 No  (2/2)  Wholemount images
Peyer's patch 2 No  (2/2)  Wholemount images
Pituitary gland 2 No  (2/2)  Wholemount images
Prostate gland 2 No  (12/584)  (1/2)  Wholemount images
Skeletal muscle 2 No  (2/2)  Wholemount images
Skin 2 No  (2/2)  Wholemount images
Small intestine 2 No  (9/584)  (2/2)  Wholemount images
Spinal cord 2 No  (2/2)  Wholemount images
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584)  (2/2)  Wholemount images
Striatum 2 No  (2/2)  Wholemount images
Testis 2 No  (2/584)  (1/2)  Wholemount images
Thymus 2 No  (2/2)  Wholemount images
Thyroid gland 2 No  (15/584)  (2/2)  Wholemount images
Trachea 2 No  (2/2)  Wholemount images
Uterus 2 No  (1/2)  Wholemount images
Vascular system 2 No  (2/2)  Wholemount images
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 1  (6/485)  (4/4) N/A
Ear 1  (1/485)  (2/4) N/A
Embryo 1  (1/485)  (4/4) N/A
Eye 1  (1/485)  (4/4) N/A
Foot 1  (1/485)  (1/4) N/A
Forebrain 1  (1/485)  (4/4) N/A
Forelimb 1  (1/485)  (4/4) N/A
Hand 1  (1/485)  (1/4) N/A
Head 1  (5/485)  (4/4) N/A
Heart 1  (1/485)  (2/4) N/A
Hindbrain 1  (6/485)  (4/4) N/A
Hindlimb 1  (1/485)  (4/4) N/A
Liver 1  (1/485)  (2/4) N/A
Lung 1  (1/485)  (2/4) N/A
Mandibular process 1  (1/485)  (2/4) N/A
Maxillary process 1  (1/485)  (2/4) N/A
Midbrain 1  (1/485)  (4/4) N/A
Oral cavity 1  (1/485)  (2/4) N/A
Skin 1  (1/485)  (2/4) N/A
Tail 1  (1/485)  (4/4) N/A
Tail somite 1  (1/485)  (2/4) N/A

 Associated Images

X-ray: XRay Images Lateral Orientation
30 Images
X-ray: XRay Images Skull Lateral Orientation
15 Images
X-ray: XRay Images Dorso Ventral
46 Images
X-ray: XRay Images Forepaw
14 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
17 Images
Adult LacZ: LacZ Images Wholemount
25 Images
Echo: M-Mode Images
44 Images
Embryo LacZ: LacZ images wholemount
4 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Usp3tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Usp3tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Usp3tm42256(pL1L2_GT2_DelLacZ_bsd) Targeting vectors

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