Gene: Alpk3

Name
alpha-kinase 3
MGI ID
MGI:2151224
Synonyms
Midori
Viability
Homozygous - Subviable
Other links
View data by physiological system
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
decreased cardiac muscle contractility Alpk3tm1b(EUCOMM)Hmgu HOM postnatal 5.02×10-08
increased heart weight Alpk3tm1b(EUCOMM)Hmgu HOM postnatal 0.00
dilated heart left ventricle Alpk3tm1b(EUCOMM)Hmgu HOM postnatal 2.53×10-21
thick ventricular wall Alpk3tm1b(EUCOMM)Hmgu HOM postnatal 1.59×10-15
preweaning lethality, incomplete penetrance Alpk3tm1b(EUCOMM)Hmgu HOM n/a 0.00
increased heart left ventricle size Alpk3tm1b(EUCOMM)Hmgu HOM postnatal 7.16×10-08
enlarged heart Alpk3tm1b(EUCOMM)Hmgu HOM postnatal 0.00

Download data as:  TSV  XLS

Filtered by: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Bone 2 No N/A
Brain 2 No  (2/2)  Wholemount images
Brainstem 2 No N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (2/2)  Wholemount images
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Esophagus 2 No  (7/415)  (2/2)  Wholemount images
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No  (2/2)  Wholemount images
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Kidney 2 No  (18/584) N/A
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No  (2/2)  Wholemount images
Lymph node 2 No N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No  (2/2)  Wholemount images
Oral epithelium 2 No N/A
Ovary 2 No  (1/584) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/584) N/A
Parathyroid gland 2 No N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No  (2/2)  Wholemount images
Skin 2 No  (2/2)  Wholemount images
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584) N/A
Striatum 2 No N/A
Testis 2 No  (2/584)  (1/2)  Wholemount images
Thymus 2 No N/A
Thyroid gland 2 No  (15/584)  (2/2)  Wholemount images
Trachea 2 No N/A
Uterus 2 No N/A
Vascular system 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/485) N/A
Ear 2  (1/485) N/A
Embryo 2  (1/485)  (4/4) N/A
Eye 2  (1/485) N/A
Foot 2  (1/485) N/A
Forebrain 2  (1/485) N/A
Forelimb 2  (1/485)  (2/4) N/A
Hand 2  (1/485) N/A
Head 2  (5/485)  (3/4) N/A
Heart 2  (1/485)  (2/4) N/A
Hindbrain 2  (6/485) N/A
Hindlimb 2  (1/485)  (2/4) N/A
Liver 2  (1/485) N/A
Lung 2  (1/485) N/A
Mandibular process 2  (1/485) N/A
Maxillary process 2  (1/485) N/A
Midbrain 2  (1/485) N/A
Oral cavity 2  (1/485) N/A
Skin 2  (1/485) N/A
Tail 2  (1/485)  (3/4) N/A
Tail somite 2  (1/485)  (1/4) N/A

 Associated Images

X-ray: XRay Images Dorso Ventral
7 Images
X-ray: XRay Images Lateral Orientation
7 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
7 Images
Echo: M-Mode Images
32 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
2 Images
Embryo LacZ: LacZ images wholemount
7 Images
Adult LacZ: LacZ Images Wholemount
10 Images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Alpk3tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Alpk3tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice

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