Gene: Alpk3

Log in to follow
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
decreased cardiac muscle contractility Alpk3tm1b(EUCOMM)Hmgu HOM   Early adult 5.76×10-13
decreased prepulse inhibition Alpk3tm1b(EUCOMM)Hmgu HOM   Early adult 2.43×10-09
enlarged heart Alpk3tm1b(EUCOMM)Hmgu HOM Early adult 0.00
increased heart left ventricle size Alpk3tm1b(EUCOMM)Hmgu HOM   Early adult 1.61×10-08
increased heart weight Alpk3tm1b(EUCOMM)Hmgu HOM   Early adult 0.00
preweaning lethality, incomplete penetrance Alpk3tm1b(EUCOMM)Hmgu HOM   Early adult 0.00
dilated heart left ventricle Alpk3tm1b(EUCOMM)Hmgu HOM   Early adult 0.00
decreased eosinophil cell number Alpk3tm1b(EUCOMM)Hmgu HOM   Early adult 9.75×10-07
thick ventricular wall Alpk3tm1b(EUCOMM)Hmgu HOM   Early adult 3.33×10-15

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (4/583) N/A
Aorta 2 No  (1/583) N/A
Bone 2 No N/A
Brain 2 No  (4/583)  (2/2)  Wholemount images
Brainstem 2 No  (2/583) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (1/583)  (2/2)  Wholemount images
Cerebellum 2 No  (3/583) N/A
Cerebral cortex 2 No  (2/583) N/A
Esophagus 2 No  (7/407)  (2/2)  Wholemount images
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No  (2/583)  (2/2)  Wholemount images
Hippocampus 2 No  (3/583) N/A
Hypothalamus 2 No  (2/583) N/A
Kidney 2 No  (21/583) N/A
Large intestine 2 No  (10/583) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (1/583) N/A
Lung 2 No  (2/583)  (2/2)  Wholemount images
Lymph node 2 No  (1/583) N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No  (2/583)  (2/2)  Wholemount images
Oral epithelium 2 No N/A
Ovary 2 No  (1/583) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/583) N/A
Parathyroid gland 2 No  (1/563) N/A
Peripheral nervous system 2 No  (2/583) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/583) N/A
Prostate gland 2 No  (12/583) N/A
Skeletal muscle 2 No  (2/2)  Wholemount images
Skin 2 No  (1/583)  (2/2)  Wholemount images
Small intestine 2 No  (9/583) N/A
Spinal cord 2 No  (3/583) N/A
Spleen 2 No  (3/583) N/A
Stomach 2 No  (13/583) N/A
Striatum 2 No  (3/583) N/A
Testis 2 No  (6/583)  (1/2)  Wholemount images
Thymus 2 No  (1/583) N/A
Thyroid gland 2 No  (17/583)  (2/2)  Wholemount images
Trachea 2 No  (3/583) N/A
Uterus 2 No N/A
Vascular system 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
2  (6/505) N/A
2  (1/505) N/A
2  (1/506)  (4/4) N/A
2  (1/505) N/A
2  (1/505) N/A
2  (1/505) N/A
2  (1/505)  (2/4) N/A
2  (1/505) N/A
2  (5/505)  (4/4) N/A
2  (1/505)  (2/4) N/A
2  (6/505) N/A
2  (1/505)  (2/4) N/A
2  (1/503) N/A
2  (1/503) N/A
2  (1/505) N/A
2  (1/505) N/A
2  (1/505) N/A
2  (1/503) N/A
2  (1/505) N/A
2  (1/505)  (3/4) N/A
2  (1/505)  (1/4) N/A

 Associated Images

X-ray: XRay Images Whole Body Lateral Orientation
7 Images
Echo: M-Mode Images
32 Images
X-ray: XRay Images Whole Body Dorso Ventral
7 Images
Adult LacZ: LacZ Images Wholemount
10 Images
Embryo LacZ: LacZ images wholemount
7 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
7 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
2 Images

 Disease Models

Please visit the desktop version to see this section

 Order Mouse and ES Cells

This service may be affected by the Covid-19 pandemic. See how

MGI Allele Allele Type Produced
Alpk3tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Alpk3tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter