Gene Summary
IMPC Data Collections
- Body Weight Measurements
- No Embryo Imaging Data
- Viability Data
The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.
Phenotype | System | Allele | Zyg | Sex | Life Stage | P Value |
---|---|---|---|---|---|---|
small kidney | Adarb2em1(IMPC)Tcp | HOM | Early adult | 0.00 | ||
small testis | Adarb2em1(IMPC)Tcp | HOM | Early adult | 0.00 | ||
abnormal coat/ hair morphology | Adarb2em1(IMPC)Tcp | HOM | Early adult | 7.32×10-08 | ||
decreased bone mineral density | Adarb2em1(IMPC)Tcp | HOM | Early adult | 6.78×10-05 | ||
limb grasping | Adarb2em1(IMPC)Tcp | HOM | Early adult | 2.99×10-06 | ||
abnormal spleen morphology | Adarb2em1(IMPC)Tcp | HOM | Early adult | 0.00 |
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
The table below shows human diseases predicted to be associated to Adarb2 by phenotypic similarity.
Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.
There is no histopathology data for Adarb2
The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Adarb2.
There are 1 publication which use IMPC produced mice or data.
Title | Journal | IMPC Allele | PubMed ID |
---|---|---|---|
Adar3 Is Involved in Learning and Memory in Mice. | Frontiers in neuroscience (April 2018) | Adarb2tm1a(KOMP)Mbp | PMC5914295 |
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MGI Allele | Allele Type | Produced |
---|---|---|
Adarb2tm42060(L1L2_gt1) | KO first allele (reporter-tagged insertion with conditional potential) | Targeting vectors |
Adarb2tm1e(KOMP)Mbp | Targeted, non-conditional allele | ES Cells |
Adarb2tm42060(L1L2_Pgk_PM) | KO first allele (reporter-tagged insertion with conditional potential) | Targeting vectors |
Adarb2em1(IMPC)Tcp | Exon Deletion | Mice |
Adarb2tm2(NCOM)Mfgc | Reporter-tagged deletion allele (with selection cassette) | Targeting vectors, ES Cells |
Adarb2tm1a(KOMP)Mbp | KO first allele (reporter-tagged insertion with conditional potential) | Targeting vectors, ES Cells |
Adarb2tm1(NCOM)Mfgc | Reporter-tagged deletion allele (with selection cassette) | Targeting vectors, ES Cells |
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