Gene: Slc4a10

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Name
solute carrier family 4, sodium bicarbonate cotransporter-like, member 10
MGI ID
MGI:2150150
Synonyms
NCBE
Viability
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
decreased bone mineral content Slc4a10tm1b(KOMP)Wtsi HOM Early adult 4.29×10-06
increased thigmotaxis Slc4a10tm1b(KOMP)Wtsi HOM Early adult 7.37×10-07
abnormal gait Slc4a10tm1b(KOMP)Wtsi HOM Early adult 5.09×10-05
hyperactivity Slc4a10tm1b(KOMP)Wtsi HOM Early adult 1.22×10-07
abnormal auditory brainstem response Slc4a10tm1b(KOMP)Wtsi HOM   Early adult 9.71×10-07
abnormal bone structure Slc4a10tm1b(KOMP)Wtsi HOM Early adult 1.51×10-05
abnormal behavior Slc4a10tm1b(KOMP)Wtsi HOM Early adult 7.37×10-07
increased anxiety-related response Slc4a10tm1b(KOMP)Wtsi HOM Early adult 1.09×10-05
small spleen Slc4a10tm1b(KOMP)Wtsi HOM Early adult 0.00
increased mean corpuscular hemoglobin Slc4a10tm1b(KOMP)Wtsi HOM Early adult 6.99×10-05

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
2 No  (4/583) N/A
2 No  (1/583) N/A
2 No N/A
2 No  (4/583)  (2/2)  Wholemount images
2 No  (2/583)  (2/2)  Wholemount images
2 No N/A
2 No  (1/583) N/A
2 No  (3/583)  (2/2)  Wholemount images
2 No  (2/583)  (2/2)  Wholemount images
2 No  (7/407) N/A
2 No N/A
2 No N/A
2 No  (2/583) N/A
2 No  (3/583)  (2/2)  Wholemount images
2 No  (2/583)  (1/2)  Wholemount images
2 No  (21/583) N/A
2 No  (10/583) N/A
2 No N/A
2 No  (1/583) N/A
2 No  (2/583) N/A
2 No  (1/583) N/A
2 No N/A
2 No  (2/583)  (2/2)  Wholemount images
2 No N/A
2 No  (1/583) N/A
2 No N/A
2 No  (5/583) N/A
2 No  (1/563) N/A
2 No  (2/583) N/A
2 No N/A
2 No  (1/583) N/A
2 No  (12/583) N/A
2 No N/A
2 No  (1/583) N/A
2 No  (9/583) N/A
2 No  (3/583) N/A
2 No  (3/583) N/A
2 No  (13/583) N/A
2 No  (3/583)  (2/2)  Wholemount images
2 No  (6/583)  (1/2)  Wholemount images
2 No  (1/583) N/A
2 No  (17/583) N/A
2 No  (3/583) N/A
2 No N/A
2 No N/A
2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
1  (6/505)  (2/2) N/A
1  (1/505) N/A
1  (1/506)  (2/2) N/A
1  (1/505) N/A
1  (1/505) N/A
1  (1/505) N/A
1  (1/505) N/A
1  (1/505) N/A
1  (5/505)  (2/2) N/A
1  (1/505) N/A
1  (6/505)  (2/2) N/A
1  (1/505) N/A
1  (1/503) N/A
1  (1/503) N/A
1  (1/505) N/A
1  (1/505) N/A
1  (1/505) N/A
1  (1/503) N/A
1  (1/505) N/A
1  (1/505) N/A
1  (1/505) N/A

 Associated Images

X-ray: XRay Images Skull Dorso Ventral Orientation
12 Images
X-ray: XRay Images Whole Body Lateral Orientation
12 Images
Echo: M-Mode Images
20 Images
Embryo LacZ: LacZ images wholemount
8 Images
X-ray: XRay Images Whole Body Dorso Ventral
12 Images
Adult LacZ: LacZ Images Wholemount
4 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Slc4a10tm356009(L1L2_Bact_P) Targeting vectors
Slc4a10tm34451(L1L2_gt2) Targeting vectors
Slc4a10tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Slc4a10tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice

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