Gene: Gopc

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Name
golgi associated PDZ and coiled-coil motif containing
MGI ID
MGI:2149946
Synonyms
GOPC1 2210402P09Rik
Viability
Embryo viewer
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal cecum morphology Gopctm1e.1(EUCOMM)Wtsi HET Early adult 0.00
preweaning lethality, incomplete penetrance Gopctm1e.1(EUCOMM)Wtsi HOM   Early adult 0.00
enlarged cecum Gopctm1e.1(EUCOMM)Wtsi HET Early adult 0.00
decreased heart weight Gopctm1e.1(EUCOMM)Wtsi HET Early adult 4.26×10-08

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Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/511) N/A
Aorta 2 No  (1/499) N/A
Blood 2 No N/A
Bone marrow 2 No N/A
Brain 2 No  (4/504) N/A
Brainstem 2 No  (2/498) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (1/507) N/A
Cecum 2 No  (8/312) N/A
Cerebellum 2 No  (3/499) N/A
Cerebral cortex 2 No  (2/510) N/A
Chest bone 2 No N/A
Colon 2 No  (9/105) N/A
Diaphragm 2 No N/A
Duodenum 2 No  (1/111) N/A
Epididymis 2 No  (14/115)  (1/2)  Section images
Esophagus 2 No  (7/354) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Gonadal fat pad 2 No N/A
Harderian gland 2 No N/A
Heart 2 No  (1/486) N/A
Hindlimb 2 No N/A
Hippocampus 2 No  (3/494) N/A
Hypothalamus 2 No  (2/492) N/A
Ileum 2 No  (12/110) N/A
Jejunum 2 No  (5/110) N/A
Kidney 2 No  (18/493)  (2/2)  Section images
Large intestine 2 No  (10/483) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (1/505) N/A
Lung 2 No  (1/505) N/A
Lymph node 2 No  (1/522) N/A
Mammary gland 2 No N/A
Mesenteric adipose tissue 2 No N/A
Mesenteric lymph node 2 No N/A
Midbrain 2 No N/A
Olfactory lobe 2 No  (2/483) N/A
Ovary 2 No N/A
Oviduct 2 No N/A
Pancreas 2 No  (4/493) N/A
Parathyroid gland 2 No  (1/477) N/A
Parotid gland 2 No N/A
Penis 2 No N/A
Peripheral nervous system 2 No  (2/501) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/509) N/A
Prostate gland 2 No  (11/507)  (1/2)  Section images
Quadriceps 2 No N/A
Sciatic nerve 2 No N/A
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (7/504) N/A
Spinal cord 2 No  (3/492) N/A
Spleen 2 No  (3/499) N/A
Stomach 2 No  (12/496) N/A
Stomach pyloric region 2 No N/A
Striatum 2 No  (2/505) N/A
Sublingual gland 2 No N/A
Submandibular gland 2 No  (2/110) N/A
Testis 2 No  (6/490)  (1/2)  Section images
Thymus 2 No  (1/502) N/A
Thyroid gland 2 No  (13/498) N/A
Tongue 2 No  (5/117)  (1/2)  Section images
Trachea 2 No  (2/504) N/A
Trigeminal V nerve 2 No N/A
Urinary bladder 2 No N/A
Uterus 2 No N/A
Vagina 2 No N/A
Vas deferens 2 No  (12/320)  (1/2)  Section images
Vascular system 2 No N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2  (1/63) N/A
Brain 2  (6/507)  (2/2) N/A
Central nervous system ganglion 2  (1/72)  (2/2) N/A
Ear 2  (1/507)  (2/2) N/A
Embryo 2  (1/508) Image Only N/A
Eye 2  (1/507)  (2/2) N/A
Footplate 2  (1/507) N/A
Forebrain 2  (1/507)  (2/2) N/A
Forelimb 2  (1/507) N/A
Gut 2  (1/58)  (2/2) N/A
Handplate 2  (1/507) N/A
Head 2  (5/507) N/A
Heart 2  (1/507)  (2/2) N/A
Hindbrain 2  (6/507)  (2/2) N/A
Hindlimb 2  (1/507) N/A
Liver 2  (1/502) N/A
Lung 2  (1/502) N/A
Mandibular process 2  (1/507) N/A
Maxillary process 2  (1/507) N/A
Midbrain 2  (1/507)  (2/2) N/A
Nose 2  (1/77) N/A
Oral cavity 2  (1/502) N/A
Skeleton 2  (1/77) N/A
Skin 2  (1/507) N/A
Spinal cord 2  (1/71) N/A
Tail 2  (1/507) N/A
Tail somite group 2  (1/507) N/A
Trachea 2  (1/58) N/A
Urinary system 2  (1/58)  (2/2) N/A

 Associated Images

Adult LacZ: LacZ Images Section
9 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images
Gross Morphology Embryo E14.5-E15.5
7 Images
Embryo LacZ: LacZ images wholemount
8 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Histopathology

 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Gopctm1e.1(EUCOMM)Wtsi Mice, Tissue
Gopctm1e(EUCOMM)Wtsi Targeted, non-conditional allele Mice
Gopctm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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