Gene: Nans

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Name
N-acetylneuraminic acid synthase (sialic acid synthase)
MGI ID
MGI:2149820
Synonyms
N-acetylneuraminic acid phosphate synthase Sas 4632418E04Rik
Viability
Embryo viewer
N/A
Other links
Expression & images (0) Disease models (0) Order (3)
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
increased total body fat amount Nansem1(IMPC)Tcp HET Early adult 3.19×10-06
preweaning lethality, complete penetrance Nansem1(IMPC)Tcp HOM   Early adult 0.00
prenatal lethality prior to heart atrial septation Nansem1(IMPC)Tcp HOM   E15.5 0.00
embryonic lethality prior to tooth bud stage Nansem1(IMPC)Tcp HOM   E12.5 0.00
decreased lean body mass Nansem1(IMPC)Tcp HET Early adult 3.77×10-11
decreased heart weight Nansem1(IMPC)Tcp HET Early adult 5.09×10-06

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Viewing: all phenotypes

 Expression

Expression data not available

 Associated Images

Eye Morphology: Images Slit Lamp
96 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images
Eye Morphology: Images Ophthalmoscopy
103 Images
Gross Morphology Embryo E14.5-E15.5
4 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images
Gross Morphology Embryo E9.5
2 Images
Electrocardiogram (ECG): Waveform Image
1 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Nanstm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Nanstm387(L1L2_gt0) Targeting vectors
Nansem1(IMPC)Tcp Exon Deletion Mice

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