Genes Phenotypes

Gene: Slc5a5

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Name
solute carrier family 5 (sodium iodide symporter), member 5
MGI ID
MGI:2149330
Synonyms
NIS
Viability
Homozygous - Viable
View
N/A
Other links
MGI   Ensembl  
Significant phenotypes (7) Measurements chart (222) All data table (302)
Expression & images (73) Disease models (0) Order (3)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
decreased bone mineral density Slc5a5tm1b(KOMP)Wtsi HOM postnatal 3.38×10-06
increased circulating cholesterol level Slc5a5tm1b(KOMP)Wtsi HOM postnatal 9.07×10-11
decreased exploration in new environment Slc5a5tm1b(KOMP)Wtsi HOM postnatal 4.64×10-05
decreased prepulse inhibition Slc5a5tm1b(KOMP)Wtsi HOM postnatal 9.88×10-05
corneal deposits Slc5a5tm1b(KOMP)Wtsi HOM postnatal 3.31×10-05
abnormal sleep behavior Slc5a5tm1b(KOMP)Wtsi HOM postnatal 8.33×10-13
increased circulating HDL cholesterol level Slc5a5tm1b(KOMP)Wtsi HOM postnatal 1.27×10-06

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Brain 2 No N/A
Brainstem 2 No N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Epididymis 2 No  (18/134) N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Heart 2 No N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Kidney 2 No  (18/584) N/A
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Midbrain 2 No N/A
Olfactory lobe 2 No N/A
Ovary 2 No  (1/584)  Section images
Oviduct 2 No N/A
Pancreas 2 No  (5/584) N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584) N/A
Striatum 2 No N/A
Submandibular gland 2 No  (2/132) N/A
Testis 2 No  (2/584)  (1/2)  Section images
Thalamus 2 No N/A
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No N/A
Urinary bladder 2 No N/A
Uterus 2 No N/A
Vascular system 2 No N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No N/A
LacZ Wholemount Images
LacZ Section Images
postnatal mouse (2)
Ovary imageOnly
MA:0000384
reproductive system (2)
Ovary imageOnly
MA:0000384
trunk (2)
Ovary imageOnly
MA:0000384
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/485) N/A
Dorsal root ganglion 2  (1/47) N/A
Ear 2  (1/485) N/A
Embryo 2  (1/485) N/A
Eye 2  (1/485) N/A
Foot 2  (1/485) N/A
Forebrain 2  (1/485) N/A
Forelimb 2  (1/485) N/A
Fronto-nasal process 2  (1/48) N/A
Hand 2  (1/485) N/A
Head 2  (5/485) N/A
Heart 2  (1/485) N/A
Hindbrain 2  (6/485) N/A
Hindlimb 2  (1/485) N/A
Liver 2  (1/485) N/A
Lung 2  (1/485) N/A
Mandibular process 2  (1/485) N/A
Maxillary process 2  (1/485) N/A
Midbrain 2  (1/485) N/A
Nose 2  (1/51) N/A
Oral cavity 2  (1/485) N/A
Skin 2  (1/485) N/A
Spinal cord 2  (1/50) N/A
Tail 2  (1/485) N/A
Tail somite 2  (1/485) N/A

 Associated Images

X-ray: XRay Images Forepaw
9 Images
X-ray: XRay Images Dorso Ventral
9 Images
X-ray: XRay Images Lateral Orientation
9 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
9 Images
Electroretinography 2: Rod and cone PDF
2 Images
X-ray: XRay Images Skull Lateral Orientation
9 Images
Original Image
Adult LacZ: LacZ Images Section
2 Images

 Disease Models

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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Slc5a5tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Slc5a5tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells
Slc5a5tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice

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