Gene: Tmem132a

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Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
syndactyly Tmem132atm1b(KOMP)Wtsi HOM embryonic day 18.5 0.00
abnormal bone structure Tmem132atm1b(KOMP)Wtsi HET postnatal 7.82×10-07
abnormal limb morphology Tmem132atm1b(KOMP)Wtsi HOM embryonic day 15.5 0.00
increased total body fat amount Tmem132atm1b(KOMP)Wtsi HET postnatal 3.01×10-05
abnormal limb morphology Tmem132atm1b(KOMP)Wtsi HOM embryonic day 18.5 0.00
preweaning lethality, complete penetrance Tmem132atm1b(KOMP)Wtsi HOM n/a 0.00
abnormal facial morphology Tmem132atm1b(KOMP)Wtsi HOM embryonic day 18.5 0.00
decreased bone mineral content Tmem132atm1b(KOMP)Wtsi HET postnatal 1.66×10-06
abnormal cranium morphology Tmem132atm1b(KOMP)Wtsi HOM embryonic day 12.5 0.00
abnormal tail morphology Tmem132atm1b(KOMP)Wtsi HOM embryonic day 18.5 0.00
increased erythrocyte cell number Tmem132atm1b(KOMP)Wtsi HET postnatal 3.28×10-05
abnormal craniofacial morphology Tmem132atm1b(KOMP)Wtsi HOM embryonic day 12.5 0.00
spina bifida Tmem132atm1b(KOMP)Wtsi HOM embryonic day 18.5 0.00
abnormal tail morphology Tmem132atm1b(KOMP)Wtsi HOM embryonic day 12.5 0.00
syndactyly Tmem132atm1b(KOMP)Wtsi HOM embryonic day 15.5 0.00
abnormal limb bud morphology Tmem132atm1b(KOMP)Wtsi HOM embryonic day 12.5 0.00
spina bifida Tmem132atm1b(KOMP)Wtsi HOM embryonic day 15.5 0.00
abnormal embryo size Tmem132atm1b(KOMP)Wtsi HOM embryonic day 18.5 0.00
abnormal neural tube closure Tmem132atm1b(KOMP)Wtsi HOM embryonic day 12.5 0.00
abnormal head shape Tmem132atm1b(KOMP)Wtsi HOM embryonic day 18.5 0.00

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Bone 2 No N/A
Brain 2 No  (2/2)  Wholemount images
Brainstem 2 No  (2/2)  Wholemount images
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cecum 2 No  (12/383) N/A
Cerebellum 2 No  (2/2)  Wholemount images
Cerebral cortex 2 No  (2/2)  Wholemount images
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No N/A
Hippocampus 2 No  (2/2)  Wholemount images
Hypothalamus 2 No  (2/2)  Wholemount images
Kidney 2 No  (18/584)  (2/2)  Wholemount images
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Mesenteric lymph node 2 No N/A
Olfactory lobe 2 No  (2/2)  Wholemount images
Oral epithelium 2 No  (2/2)  Wholemount images
Ovary 2 No  (1/584) N/A
Oviduct 2 No  (1/2)  Wholemount images
Pancreas 2 No  (5/584) N/A
Parathyroid gland 2 No N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (2/2)  Wholemount images
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584) N/A
Striatum 2 No  (2/2)  Wholemount images
Testis 2 No  (2/584)  (1/2)  Wholemount images
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No N/A
Trigeminal V nerve 2 No N/A
Urinary bladder 2 No N/A
Uterus 2 No N/A
Vas deferens 2 No  (15/388) N/A
Vascular system 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Heart atrium 4  (1/47)  (4/4) N/A
Axial skeleton 4  (1/51)  (4/4) N/A
Brain 4  (6/485)  (4/4) N/A
Central nervous system ganglion 4  (1/51)  (4/4) N/A
Cranium 4  (1/46)  (4/4) N/A
Dorsal root ganglion 4  (1/47)  (4/4) N/A
Ear 4  (1/485)  (4/4) N/A
Embryo 4  (1/485)  (4/4) N/A
Outer ear 4  (1/47)  (4/4) N/A
Eye 4  (1/485)  (4/4) N/A
Femur pre-cartilage condensation 4  (1/46)  (4/4) N/A
Foot 4  (1/485)  (4/4) N/A
Forearm 4  (1/282)  (4/4) N/A
Forebrain 4  (1/485)  (4/4) N/A
Forelimb 4  (1/485)  (4/4) N/A
Fronto-nasal process 4  (1/48)  (4/4) N/A
Gut 4  (1/50)  (4/4) N/A
Hand 4  (1/485)  (4/4) N/A
Head 4  (5/485)  (4/4) N/A
Head mesenchyme 4  (1/47)  (4/4) N/A
Heart 4  (1/485)  (4/4) N/A
Heart ventricle 4  (1/47)  (4/4) N/A
Hindbrain 4  (6/485)  (4/4) N/A
Hindlimb 4  (1/485)  (4/4) N/A
Humerus pre-cartilage condensation 4  (1/46)  (4/4) N/A
Inner ear 4  (1/46)  (4/4) N/A
Intestine 4  (1/47)  (3/4) N/A
Liver 4  (1/485)  (4/4) N/A
Lower leg 4  (1/282)  (4/4) N/A
Lung 4  (1/485)  (4/4) N/A
Mandibular process 4  (1/485)  (4/4) N/A
Maxillary process 4  (1/485)  (4/4) N/A
Mesonephros of female 4  (1/46)  (4/4) N/A
Mesonephros of male 4  (1/46)  (4/4) N/A
Metanephros 4  (1/46)  (4/4) N/A
Midbrain 4  (1/485)  (4/4) N/A
Nasal septum 4  (1/47)  (4/4) N/A
Nose 4  (1/51)  (4/4) N/A
Notochord 4  (1/47)  (4/4) N/A
Oral cavity 4  (1/485)  (4/4) N/A
Outflow tract 4  (1/47)  (4/4) N/A
Pancreas 4  (1/46)  (4/4) N/A
Pericardium 4  (1/46)  (4/4) N/A
Pharynx 4  (1/46)  (4/4) N/A
Radius-ulna pre-cartilage condensation 4  (1/46)  (4/4) N/A
Rib pre-cartilage condensation 4  (1/46)  (4/4) N/A
Skeleton 4  (1/51)  (4/4) N/A
Skin 4  (1/485)  (4/4) N/A
Spinal cord 4  (1/50)  (4/4) N/A
Stomach 4  (1/46)  (4/4) N/A
Tail 4  (1/485)  (4/4) N/A
Tail somite 4  (1/485)  (4/4) N/A
Thoracic vertebral cartilage condensation 4  (1/46)  (4/4) N/A
Tongue 4  (1/46)  (4/4) N/A
Trachea 4  (1/50)  (4/4) N/A
Trunk mesenchyme 4  (1/47)  (4/4) N/A
Umbilical artery embryonic part 4  (1/47)  (4/4) N/A
Umbilical vein embryonic part 4  (1/47)  (4/4) N/A
Upper arm 4  (1/282)  (4/4) N/A
Upper leg 4  (1/282)  (4/4) N/A
Urinary system 4  (1/50)  (4/4) N/A
Vibrissa 4  (1/47)  (4/4) N/A

 Associated Images

X-ray: XRay Images Lateral Orientation
10 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
X-ray: XRay Images Forepaw
10 Images
X-ray: XRay Images Dorso Ventral
10 Images
Adult LacZ: LacZ Images Wholemount
7 Images
Embryo LacZ: LacZ images wholemount
4 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Tmem132atm2a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Tmem132atm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Tmem132atm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue

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