Gene: Tmem132a

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Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
increased total body fat amount Tmem132atm1b(KOMP)Wtsi HET Early adult 8.24×10-11
abnormal limb morphology Tmem132atm1b(KOMP)Wtsi HOM E18.5 0.00
abnormal neural tube closure Tmem132atm1b(KOMP)Wtsi HOM E12.5 0.00
decreased lean body mass Tmem132atm1b(KOMP)Wtsi HET Early adult 6.05×10-07
abnormal limb morphology Tmem132atm1b(KOMP)Wtsi HOM E15.5 0.00
abnormal tail morphology Tmem132atm1b(KOMP)Wtsi HOM E12.5 0.00
abnormal craniofacial morphology Tmem132atm1b(KOMP)Wtsi HOM E12.5 0.00
abnormal ear morphology Tmem132atm1b(KOMP)Wtsi HET E15.5 0.00
abnormal tail morphology Tmem132atm1b(KOMP)Wtsi HOM E15.5 0.00
abnormal tail morphology Tmem132atm1b(KOMP)Wtsi HOM E18.5 0.00
abnormal craniofacial morphology Tmem132atm1b(KOMP)Wtsi HET E15.5 0.00
abnormal facial morphology Tmem132atm1b(KOMP)Wtsi HOM E18.5 0.00
abnormal embryo size Tmem132atm1b(KOMP)Wtsi HOM E18.5 0.00
abnormal cranium morphology Tmem132atm1b(KOMP)Wtsi HOM E12.5 0.00
abnormal limb bud morphology Tmem132atm1b(KOMP)Wtsi HOM E12.5 0.00
abnormal bone mineralization Tmem132atm1b(KOMP)Wtsi HET Early adult 6.38×10-06
preweaning lethality, complete penetrance Tmem132atm1b(KOMP)Wtsi HOM Early adult 0.00
abnormal head shape Tmem132atm1b(KOMP)Wtsi HOM E18.5 0.00
abnormal bone structure Tmem132atm1b(KOMP)Wtsi HET Early adult 1.05×10-08
abnormal pericardium morphology Tmem132atm1b(KOMP)Wtsi HOM E12.5 0.00
decreased bone mineral content Tmem132atm1b(KOMP)Wtsi HET Early adult 3.08×10-07
abnormal embryonic autopod plate morphology Tmem132atm1b(KOMP)Wtsi HOM E12.5 0.00

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (3/589) N/A
Aorta 2 No  (1/589) N/A
Bone 2 No N/A
Brain 2 No  (3/589)  (2/2)  Wholemount images
Brainstem 2 No  (2/589)  (2/2)  Wholemount images
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cecum 2 No  (12/379) N/A
Cerebellum 2 No  (3/589)  (2/2)  Wholemount images
Cerebral cortex 2 No  (2/589)  (2/2)  Wholemount images
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No  (1/589) N/A
Hippocampus 2 No  (3/589)  (2/2)  Wholemount images
Hypothalamus 2 No  (2/589)  (2/2)  Wholemount images
Kidney 2 No  (20/589)  (2/2)  Wholemount images
Large intestine 2 No  (10/589) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (1/589) N/A
Lung 2 No  (1/589) N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Mesenteric lymph node 2 No N/A
Olfactory lobe 2 No  (2/589)  (2/2)  Wholemount images
Oral epithelium 2 No  (2/2)  Wholemount images
Ovary 2 No  (1/589) N/A
Oviduct 2 No  (1/2)  Wholemount images
Pancreas 2 No  (5/589) N/A
Parathyroid gland 2 No N/A
Peripheral nervous system 2 No  (1/589) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/589) N/A
Prostate gland 2 No  (12/589) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (2/2)  Wholemount images
Small intestine 2 No  (9/589) N/A
Spinal cord 2 No  (2/589) N/A
Spleen 2 No  (2/589) N/A
Stomach 2 No  (13/589) N/A
Striatum 2 No  (3/589)  (2/2)  Wholemount images
Testis 2 No  (5/589)  (1/2)  Wholemount images
Thymus 2 No N/A
Thyroid gland 2 No  (16/589) N/A
Trachea 2 No  (2/589) N/A
Trigeminal V nerve 2 No N/A
Urinary bladder 2 No N/A
Uterus 2 No N/A
Vas deferens 2 No  (15/388) N/A
Vascular system 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Heart atrium 4  (1/61)  (4/4) N/A
Axial skeleton 4  (1/65)  (4/4) N/A
Brain 4  (6/506)  (4/4) N/A
Central nervous system ganglion 4  (1/74)  (4/4) N/A
Cranium 4  (1/65)  (4/4) N/A
Dorsal root ganglion 4  (1/61)  (4/4) N/A
Ear 4  (1/506)  (4/4) N/A
Embryo 4  (1/507)  (4/4) N/A
Outer ear 4  (1/70)  (4/4) N/A
Eye 4  (1/506)  (4/4) N/A
Femur pre-cartilage condensation 4  (1/56)  (4/4) N/A
Foot 4  (1/506)  (4/4) N/A
Forearm 4  (1/301)  (4/4) N/A
Forebrain 4  (1/506)  (4/4) N/A
Forelimb 4  (1/506)  (4/4) N/A
Fronto-nasal process 4  (1/62)  (4/4) N/A
Gut 4  (1/60)  (4/4) N/A
Hand 4  (1/505)  (4/4) N/A
Head 4  (5/506)  (4/4) N/A
Head mesenchyme 4  (1/61)  (4/4) N/A
Heart 4  (1/506)  (4/4) N/A
Heart ventricle 4  (1/61)  (4/4) N/A
Hindbrain 4  (6/506)  (4/4) N/A
Hindlimb 4  (1/505)  (4/4) N/A
Humerus pre-cartilage condensation 4  (1/65)  (4/4) N/A
Inner ear 4  (1/65)  (4/4) N/A
Intestine 4  (1/59)  (3/4) N/A
Liver 4  (1/506)  (4/4) N/A
Lower leg 4  (1/301)  (4/4) N/A
Lung 4  (1/502)  (4/4) N/A
Mandibular process 4  (1/506)  (4/4) N/A
Maxillary process 4  (1/506)  (4/4) N/A
Mesonephros of female 4  (1/56)  (4/4) N/A
Mesonephros of male 4  (1/56)  (4/4) N/A
Metanephros 4  (1/56)  (4/4) N/A
Midbrain 4  (1/506)  (4/4) N/A
Nasal septum 4  (1/61)  (4/4) N/A
Nose 4  (1/74)  (4/4) N/A
Notochord 4  (1/61)  (4/4) N/A
Oral cavity 4  (1/506)  (4/4) N/A
Outflow tract 4  (1/61)  (4/4) N/A
Pancreas 4  (1/56)  (4/4) N/A
Pericardium 4  (1/56)  (4/4) N/A
Pharynx 4  (1/56)  (4/4) N/A
Radius-ulna pre-cartilage condensation 4  (1/65)  (4/4) N/A
Rib pre-cartilage condensation 4  (1/58)  (4/4) N/A
Skeleton 4  (1/74)  (4/4) N/A
Skin 4  (1/506)  (4/4) N/A
Spinal cord 4  (1/73)  (4/4) N/A
Stomach 4  (1/56)  (4/4) N/A
Tail 4  (1/506)  (4/4) N/A
Tail somite 4  (1/506)  (4/4) N/A
Thoracic vertebral cartilage condensation 4  (1/56)  (4/4) N/A
Tongue 4  (1/56)  (4/4) N/A
Trachea 4  (1/60)  (4/4) N/A
Trunk mesenchyme 4  (1/61)  (4/4) N/A
Umbilical artery embryonic part 4  (1/61)  (4/4) N/A
Umbilical vein embryonic part 4  (1/61)  (4/4) N/A
Upper arm 4  (1/301)  (4/4) N/A
Upper leg 4  (1/301)  (4/4) N/A
Urinary system 4  (1/60)  (4/4) N/A
Vibrissa 4  (1/70)  (4/4) N/A

 Associated Images

X-ray: XRay Images Skull Lateral Orientation
16 Images
X-ray: XRay Images Whole Body Lateral Orientation
16 Images
Adult LacZ: LacZ Images Wholemount
15 Images
X-ray: XRay Images Forepaw
16 Images
X-ray: XRay Images Whole Body Dorso Ventral
16 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
16 Images
MicroCT E14.5-E15.5: Embryo reconstruction
1 Images
Embryo LacZ: LacZ images wholemount
4 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Tmem132atm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Tmem132atm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Tmem132atm2a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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