Genes Phenotypes

Gene: Otub1

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Name
OTU domain, ubiquitin aldehyde binding 1
MGI ID
MGI:2147616
Synonyms
N/A
Viability
Homozygous - Lethal
Embryo viewer
3D Imaging
Other links
MGI   Ensembl  
Significant phenotypes (7) Measurements chart (272) All data table (997)
Expression & images (68) Disease models (0) Order (3)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
preweaning lethality, complete penetrance Otub1tm1b(EUCOMM)Hmgu HOM Early adult 0.00
decreased grip strength Otub1tm1b(EUCOMM)Hmgu HET Early adult 3.87×10-08
decreased lean body mass Otub1tm1b(EUCOMM)Hmgu HET Early adult 1.03×10-06
abnormal heart position or orientation Otub1tm1b(EUCOMM)Hmgu HET Early adult 0.00
abnormal lung morphology Otub1tm1b(EUCOMM)Hmgu HET Early adult 0.00
embryonic lethality prior to tooth bud stage Otub1tm1b(EUCOMM)Hmgu HOM E12.5 0.00
abnormal cranium morphology Otub1tm1b(EUCOMM)Hmgu HET Early adult 9.15×10-05

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (2/2)  Wholemount images
Aorta 2 No N/A
Bone 2 No N/A
Brain 2 No  (2/2)  Wholemount images
Brainstem 2 No  (2/2)  Wholemount images
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (2/2)  Wholemount images
Cerebellum 2 No  Wholemount images
Cerebral cortex 2 No  (2/2)  Wholemount images
Esophagus 2 No  (7/415) N/A
Eye 2 No  (2/2)  Wholemount images
Gall bladder 2 No N/A
Heart 2 No N/A
Hippocampus 2 No  (2/2)  Wholemount images
Hypothalamus 2 No  (2/2)  Wholemount images
Kidney 2 No  (18/584)  (2/2)  Wholemount images
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (2/2)  Wholemount images
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No  (2/2)  Wholemount images
Oral epithelium 2 No  (2/2)  Wholemount images
Ovary 2 No  (1/584) N/A
Oviduct 2 No  (1/2)  Wholemount images
Pancreas 2 No  (5/584) N/A
Parathyroid gland 2 No  (2/2)  Wholemount images
Peripheral nervous system 2 No  (2/2)  Wholemount images
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/2)  Wholemount images
Prostate gland 2 No  (12/584)  (1/2)  Wholemount images
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No  (2/2)  Wholemount images
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584)  (1/2)  Wholemount images
Striatum 2 No  (2/2)  Wholemount images
Testis 2 No  (2/584)  (1/2)  Wholemount images
Thymus 2 No N/A
Thyroid gland 2 No  (15/584)  Wholemount images
Trachea 2 No  (2/2)  Wholemount images
Uterus 2 No N/A
Vascular system 2 No N/A
White adipose tissue 2 No N/A
LacZ Wholemount Images
digestive system (2)
Oral epithelium expression
MA:0000344
endocrine system (2)
Adrenal gland expression
MA:0000116
exocrine system (1)
Lower Urinary Tract expression
Prostate gland expression
MA:0002636
MA:0000404
nervous system (5)
Cerebral Cortex expression
Striatum expression
Hippocampus expression
Hypothalamus expression
Cerebellum ambiguous
Brainstem expression
Brain expression
MA:0000185
MA:0000891
MA:0000191
MA:0000173
MA:0000198
MA:0000169
MA:0000168
postnatal mouse (15)
Adrenal gland expression
MA:0000116
reproductive system (3)
Lower Urinary Tract expression
Prostate gland expression
MA:0002636
MA:0000404
respiratory system (2)
Oral epithelium expression
MA:0000344
sensory organ (1)
Eye expression
MA:0000261
set of connective tissues (1)
Cartilage tissue expression
MA:0000104
trunk (8)
Adrenal gland expression
MA:0000116
urinary system (2)
Kidney expression
MA:0000368
LacZ Section Images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 3  (6/504)  (3/7) N/A
Ear 3  (1/504)  (3/7) N/A
Embryo 3  (1/505)  (7/7) N/A
Eye 3  (1/504)  (7/7) N/A
Foot 3  (1/504)  (2/7) N/A
Forebrain 3  (1/504)  (5/7) N/A
Forelimb 3  (1/504)  (5/7) N/A
Hand 3  (1/503)  (2/7) N/A
Head 3  (5/504)  (7/7) N/A
Heart 3  (1/504)  (3/7) N/A
Hindbrain 3  (6/504)  (1/7) N/A
Hindlimb 3  (1/503)  (5/7) N/A
Liver 3  (1/504)  (1/7) N/A
Lung 3  (1/500)  (3/7) N/A
Mandibular process 3  (1/504)  (3/7) N/A
Maxillary process 3  (1/504)  (3/7) N/A
Midbrain 3  (1/504)  (1/7) N/A
Oral cavity 3  (1/504)  (3/7) N/A
1  (7/37)  (2/2) N/A
Skin 3  (1/504)  (3/7) N/A
Tail 3  (1/504)  (3/7) N/A
Tail somite 3  (1/504)  (1/7) N/A

 Associated Images

Embryo LacZ: LacZ images wholemount
10 Images
X-ray: XRay Images Whole Body Lateral Orientation
20 Images
X-ray: XRay Images Whole Body Dorso Ventral
20 Images
Adult LacZ: LacZ Images Wholemount
15 Images
Echo: M-Mode Images
31 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Otub1tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice
Otub1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Otub1tm83433(L1L2_Bact_P) Targeting vectors

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