Gene Summary
IMPC Data Collections
- Body Weight Measurements
- No Embryo Imaging Data
- Viability Data
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
The table below shows human diseases predicted to be associated to Gpr137 by phenotypic similarity.
Disease | Similarity of phenotypes |
Matching phenotypes | Source |
---|---|---|---|
Attention Deficit-Hyperactivity Disorder | Hyperactivity, Attention deficit hyperactivity disorder | OMIM:143465 | |
Attention Deficit-Hyperactivity Disorder 8 | Attention deficit hyperactivity disorder | OMIM:619957 | |
Schizophrenia 15 | Hyperactivity | OMIM:613950 | |
Potocki-Lupski syndrome (17p11.2 duplication syndrome) | Hyperactivity | DECIPHER:19 | |
Autism, Susceptibility To, 20 | Attention deficit hyperactivity disorder | OMIM:618830 | |
Attention Deficit-Hyperactivity Disorder, Susceptibility To, 7 | Attention deficit hyperactivity disorder | OMIM:613003 | |
22q13 deletion syndrome (Phelan-Mcdermid syndrome) | Hyperactivity | DECIPHER:20 | |
Intellectual Developmental Disorder, Autosomal Recessive 3 | Hyperactivity | OMIM:608443 | |
Intellectual Developmental Disorder, X-Linked 77 | Hyperactivity | OMIM:300454 | |
Intellectual Developmental Disorder, X-Linked 72 | Hyperactivity | OMIM:300271 | |
Intellectual Developmental Disorder, Autosomal Dominant 33 | Hyperactivity | OMIM:616311 | |
Intellectual Disability-Expressive Aphasia-Facial Dysmorphism Syndrome | Hyperactivity | ORPHA:436151 | |
Smith-Magenis syndrome | Hyperactivity | DECIPHER:8 | |
Intellectual Developmental Disorder, X-Linked, Syndromic, Houge Type | Impulsivity, Hyperactivity, Attention deficit hyperactivity disorder | OMIM:301008 | |
Developmental And Epileptic Encephalopathy 43 | Impulsivity, Hyperactivity, Attention deficit hyperactivity disorder | OMIM:617113 | |
Hartnup Disorder | Hyperactivity, Attention deficit hyperactivity disorder | OMIM:234500 | |
Developmental And Epileptic Encephalopathy 104 | Hyperactivity, Agitation | OMIM:619970 | |
Hyperlysinemia, Type I | Hyperactivity | OMIM:238700 | |
Intellectual Developmental Disorder, X-Linked 109 | Impulsivity, Hyperactivity, Agitation | OMIM:309548 | |
Intellectual Developmental Disorder, X-Linked, Syndromic, Pilorge Type | Hyperactivity | OMIM:301076 | |
8p23.1 deletion syndrome | Hyperactivity | DECIPHER:39 | |
Intellectual Developmental Disorder, X-Linked 101 | Hyperactivity | OMIM:300928 | |
Glycine Encephalopathy | Impulsivity, Hyperactivity, Restlessness | OMIM:605899 | |
Language Delay And Attention Deficit-Hyperactivity Disorder/Cognitive Impairment With Or Without Cardiac Arrhythmia | Hyperactivity, Attention deficit hyperactivity disorder | OMIM:617182 | |
Histidinemia | Hyperactivity | ORPHA:2157 |
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MGI Allele | Allele Type | Produced |
---|---|---|
Gpr137tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | ES Cells |
Gpr137tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | Targeting vectors, ES Cells |
Gpr137em1(IMPC)J | Exon Deletion | Mice |
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