Not currently registered for phenotyping at IMPC
Phenotyping is currently not planned for a knockout strain of this gene.
Gene Summary
IMPC Data Collections
- No Body Weight Data
- No Embryo Imaging Data
- No Viability Data
Phenotyping is currently not planned for a knockout strain of this gene.
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
The table below shows human diseases predicted to be associated to Slc39a3 by phenotypic similarity.
Disease | Similarity of phenotypes |
Matching phenotypes | Source |
---|---|---|---|
Okt4 Epitope Deficiency | Abnormal T cell morphology | OMIM:613949 | |
Combined Cellular And Humoral Immune Defects With Granulomas | T lymphocytopenia, B lymphocytopenia | OMIM:233650 | |
22q11 deletion syndrome (Velocardiofacial / DiGeorge syndrome) | T lymphocytopenia | DECIPHER:16 | |
Neutropenia, Severe Congenital, 2, Autosomal Dominant | Monocytosis, B lymphocytopenia, Neutropenia | OMIM:613107 | |
Combined Immunodeficiency Due To Partial Rag1 Deficiency | Autoimmune hemolytic anemia, Splenomegaly, Neutropenia in presence of anti-neutropil antibodies, ... | ORPHA:231154 |
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MGI Allele | Allele Type | Produced |
---|---|---|
Slc39a3tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | ES Cells |
Slc39a3tm48766(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | Targeting vectors |
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