Fbxo11 | F-box protein 11
Physiological systems
22 / 24 physiological systems tested
10 Significantly impacted by the knock-out
Homeostasis/metabolism Growth/size/body region Limbs/digits/tail Nervous system Vision/eye Digestive/alimentary Hematopoietic system Behavior/neurological Skeleton Mortality/aging
12 No significant impact
2 Not tested
Gene metrics:24Significant phenotypes
1Associated diseases
Expression examined in:46Adult tissues
42Embryo tissues
abnormal bone mineralization | 1 supporting dataset | Fbxo11Jf | heterozygote | Early adult | 8.65x10-5 | ||
decreased circulating iron level | 1 supporting dataset | Fbxo11tm2b(EUCOMM)Wtsi | heterozygote | Early adult | 1.23x10-6 | ||
increased startle reflex | 6 supporting datasets | Fbxo11Jf | heterozygote | Early adult | 1.01x10-19 | ||
hyperactivity | 8 supporting datasets | Fbxo11tm2b(EUCOMM)Wtsi | heterozygote | Early adult | 6.54x10-7 | ||
decreased prepulse inhibition | 4 supporting datasets | Fbxo11Jf | heterozygote | Early adult | 2.73x10-7 | ||
decreased hemoglobin content | 1 supporting dataset | Fbxo11tm2b(EUCOMM)Wtsi | heterozygote | Early adult | 2.28x10-11 | ||
decreased mean corpuscular volume | 1 supporting dataset | Fbxo11Jf | heterozygote | Early adult | 5.16x10-5 | ||
preweaning lethality, complete penetrance | 1 supporting dataset | Fbxo11Jf | homozygote | Early adult | N/A * | ||
decreased hematocrit | 1 supporting dataset | Fbxo11tm2b(EUCOMM)Wtsi | heterozygote | Early adult | 3.18x10-8 | ||
abnormal defecation | 1 supporting dataset | Fbxo11Jf | heterozygote | Early adult | 6.95x10-7 |
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External links
No external links available for Fbxo11.
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Fbxo11tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
Fbxo11tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |
Fbxo11tm2a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
Fbxo11tm2b(EUCOMM)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
Fbxo11tm2e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |