Gene: Fbxo11

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Phenotype System Allele Zyg Sex Life Stage P Value
increased startle reflex Fbxo11Jf HET Early adult 1.01×10-19
abnormal defecation Fbxo11Jf HET Early adult 6.95×10-07
decreased mean corpuscular volume Fbxo11Jf HET Early adult 8.63×10-05
decreased circulating total protein level Fbxo11tm2b(EUCOMM)Wtsi HET Early adult 1.03×10-05
hyperactivity Fbxo11tm2b(EUCOMM)Wtsi HET   Early adult 6.72×10-07
abnormal startle reflex Fbxo11Jf HET Early adult 6.68×10-12
abnormal retina morphology Fbxo11Jf HET Early adult 9.64×10-05
decreased hemoglobin content Fbxo11tm2b(EUCOMM)Wtsi HET Early adult 2.96×10-11
hyperactivity Fbxo11Jf HET Early adult 3.12×10-05
decreased hematocrit Fbxo11tm2b(EUCOMM)Wtsi HET Early adult 4.05×10-08
short tibia Fbxo11tm2b(EUCOMM)Wtsi HET Early adult 8.26×10-06
abnormal locomotor activation Fbxo11Jf HET Early adult 8.09×10-08
decreased circulating iron level Fbxo11tm2b(EUCOMM)Wtsi HET Early adult 1.13×10-06
increased red blood cell distribution width Fbxo11tm2b(EUCOMM)Wtsi HET Early adult 1.69×10-06
preweaning lethality, complete penetrance Fbxo11tm2b(EUCOMM)Wtsi HOM   Early adult 0.00
decreased erythrocyte cell number Fbxo11tm2b(EUCOMM)Wtsi HET Early adult 1.09×10-10
abnormal vocalization Fbxo11Jf HET Early adult 8.78×10-05

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
2 No  (4/584)  (2/2)  Wholemount images
2 No  (1/584)  (2/2)  Wholemount images
2 No  (2/2)  Wholemount images
2 No  (4/584)  (2/2)  Wholemount images
2 No  (2/584)  (2/2)  Wholemount images
2 No  (2/2)  Wholemount images
2 No  (1/584)  (2/2)  Wholemount images
2 No  (3/584)  (2/2)  Wholemount images
2 No  (2/584)  (2/2)  Wholemount images
2 No  (7/408)  (2/2)  Wholemount images
2 No  (2/2)  Wholemount images
2 No  (2/2)  Wholemount images
2 No  (2/584)  (2/2)  Wholemount images
2 No  (3/584)  (2/2)  Wholemount images
2 No  (2/584)  (2/2)  Wholemount images
2 No  (21/584)  (2/2)  Wholemount images
2 No  (10/584)  (2/2)  Wholemount images
2 No N/A
2 No  (1/584)  (2/2)  Wholemount images
2 No  (2/584)  (2/2)  Wholemount images
2 No  (1/584)  (2/2)  Wholemount images
2 No  (1/2)  Wholemount images
2 No  (2/584)  (2/2)  Wholemount images
2 No N/A
2 No  (1/584)  (1/2)  Wholemount images
2 No  (1/2)  Wholemount images
2 No  (5/584)  (2/2)  Wholemount images
2 No  (1/562)  (2/2)  Wholemount images
2 No  (2/584)  (2/2)  Wholemount images
2 No  (2/2)  Wholemount images
2 No  (1/584)  (2/2)  Wholemount images
2 No  (12/584)  (1/2)  Wholemount images
2 No  (2/2)  Wholemount images
2 No  (1/584)  (2/2)  Wholemount images
2 No  (9/584)  (2/2)  Wholemount images
2 No  (3/584)  (2/2)  Wholemount images
2 No  (3/584)  (2/2)  Wholemount images
2 No  (12/584)  (2/2)  Wholemount images
2 No  (3/584)  (2/2)  Wholemount images
2 No  (6/584)  (1/2)  Wholemount images
2 No  (1/584)  (2/2)  Wholemount images
2 No  (16/584)  (2/2)  Wholemount images
2 No  (3/584)  (2/2)  Wholemount images
2 No  (1/2)  Wholemount images
2 No  (2/2)  Wholemount images
2 No  Wholemount images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/507)  (4/4) N/A
Ear 2  (1/507)  (2/4) N/A
Embryo 2  (1/508)  (4/4) N/A
Eye 2  (1/507)  (4/4) N/A
Footplate 2  (1/507)  (4/4) N/A
Forebrain 2  (1/507)  (4/4) N/A
Forelimb 2  (1/507)  (4/4) N/A
Handplate 2  (1/507)  (4/4) N/A
Head 2  (5/507)  (4/4) N/A
Heart 2  (1/507)  (2/4) N/A
Hindbrain 2  (6/507)  (4/4) N/A
Hindlimb 2  (1/507)  (4/4) N/A
Liver 2  (1/502)  (2/4) N/A
Lung 2  (1/502)  (2/4) N/A
Mandibular process 2  (1/507)  (2/4) N/A
Maxillary process 2  (1/507)  (2/4) N/A
Midbrain 2  (1/507)  (3/4) N/A
Oral cavity 2  (1/502)  (2/4) N/A
Skin 2  (1/507)  (2/4) N/A
Tail 2  (1/507)  (4/4) N/A
Tail somite group 2  (1/507)  (4/4) N/A

 Associated Images

Adult LacZ: LacZ Images Wholemount
27 Images
X-ray: XRay Images Whole Body Dorso Ventral
9 Images
Echo: M-Mode Images
28 Images
Embryo LacZ: LacZ images wholemount
8 Images
X-ray: XRay Images Whole Body Lateral Orientation
9 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
8 Images
X-ray: XRay Images Skull Lateral Orientation
1 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images

 Disease Models

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 Histopathology

 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Fbxo11tm2a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Fbxo11tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Fbxo11tm2b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice

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