Gene: Scrib

Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal craniofacial morphology Scribtm1b(NCOM)Mfgc HOM embryonic day 12.5 0.00
abnormal hindbrain morphology Scribtm1b(NCOM)Mfgc HOM embryonic day 12.5 0.00
abnormal eye morphology Scribtm1b(NCOM)Mfgc HOM embryonic day 12.5 0.00
short tibia Scribtm1b(NCOM)Mfgc HET postnatal 7.15×10-05
embryonic growth retardation Scribtm1b(NCOM)Mfgc HOM embryonic day 9.5 0.00
preweaning lethality, complete penetrance Scribtm1b(NCOM)Mfgc HOM n/a 0.00
abnormal midbrain morphology Scribtm1b(NCOM)Mfgc HOM embryonic day 12.5 0.00
prenatal lethality prior to heart atrial septation Scribtm1b(NCOM)Mfgc HOM embryonic day 14.5 0.00
abnormal neural tube closure Scribtm1b(NCOM)Mfgc HOM embryonic day 12.5 0.00
abnormal pericardium morphology Scribtm1b(NCOM)Mfgc HOM embryonic day 12.5 0.00
abnormal embryo size Scribtm1b(NCOM)Mfgc HOM embryonic day 12.5 0.00
abnormal embryo size Scribtm1b(NCOM)Mfgc HOM embryonic day 15.5 0.00
pale yolk sac Scribtm1b(NCOM)Mfgc HOM embryonic day 12.5 0.00
abnormal neural tube closure Scribtm1b(NCOM)Mfgc HOM embryonic day 9.5 0.00
decreased lean body mass Scribtm1b(NCOM)Mfgc HET postnatal 6.21×10-05
abnormal embryo size Scribtm1b(NCOM)Mfgc HOM embryonic day 9.5 0.00
abnormal placenta size Scribtm1b(NCOM)Mfgc HOM embryonic day 12.5 0.00
abnormal craniofacial morphology Scribtm1b(NCOM)Mfgc HOM embryonic day 15.5 0.00

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 Expression

IMPC lacZ Expression Data

No Adult expression data was found for this gene.
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2  (1/51)  (2/2) N/A
Brain 2  (6/485)  (2/3) N/A
Central nervous system ganglion 2  (1/51)  (2/2) N/A
Ear 2  (1/485)  (2/3) N/A
Embryo 2  (1/485)  (2/3) N/A
Eye 2  (1/485)  (2/3) N/A
Foot 2  (1/485)  (2/3) N/A
Forebrain 2  (1/485)  (2/3) N/A
Forelimb 2  (1/485)  (2/3) N/A
Gut 2  (1/50)  (2/2) N/A
Hand 2  (1/485)  (2/3) N/A
Head 2  (5/485)  (2/3) N/A
Heart 2  (1/485)  (2/3) N/A
Hindbrain 2  (6/485)  (2/3) N/A
Hindlimb 2  (1/485)  (2/3) N/A
Liver 2  (1/485)  (2/3) N/A
Lung 2  (1/485)  (2/3) N/A
Mandibular process 2  (1/485)  (2/3) N/A
Maxillary process 2  (1/485)  (2/3) N/A
Midbrain 2  (1/485)  (2/3) N/A
Nose 2  (1/51)  (2/2) N/A
Oral cavity 2  (1/485)  (2/3) N/A
Skeleton 2  (1/51)  (2/2) N/A
Skin 2  (1/485)  (2/3) N/A
Spinal cord 2  (1/50)  (2/2) N/A
Tail 2  (1/485)  (2/3) N/A
Tail somite 2  (1/485)  (2/3) N/A
Trachea 2  (1/50)  (2/2) N/A
Urinary system 2  (1/50)  (2/2) N/A

 Associated Images

X-ray: XRay Images Dorso Ventral
10 Images
X-ray: XRay Images Lateral Orientation
10 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images
Combined SHIRPA and Dysmorphology
1 Images
Gross Pathology and Tissue Collection
8 Images
Eye Morphology: Images Ophthalmoscopy
13 Images
Histopathology
3 Images
Gross Morphology Embryo E14.5-E15.5
4 Images
Gross Morphology Embryo E9.5
6 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Scribtm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Scribtm1b(NCOM)Mfgc Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Scribtm1a(NCOM)Mfgc KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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