Gene: Scrib

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Phenotype System Allele Zyg Sex Life Stage P Value
abnormal hindbrain morphology Scribtm1b(NCOM)Mfgc HOM E12.5 0.00
abnormal eye morphology Scribtm1b(NCOM)Mfgc HOM E12.5 0.00
abnormal craniofacial morphology Scribtm1b(NCOM)Mfgc HOM E12.5 0.00
abnormal craniofacial morphology Scribtm1b(NCOM)Mfgc HOM E15.5 0.00
abnormal midbrain morphology Scribtm1b(NCOM)Mfgc HOM E12.5 0.00
abnormal placenta size Scribtm1b(NCOM)Mfgc HOM E12.5 0.00
abnormal embryo size Scribtm1b(NCOM)Mfgc HOM E9.5 0.00
abnormal pericardium morphology Scribtm1b(NCOM)Mfgc HOM E12.5 0.00
abnormal neural tube closure Scribtm1b(NCOM)Mfgc HOM E9.5 0.00
pale yolk sac Scribtm1b(NCOM)Mfgc HOM E12.5 0.00
decreased grip strength Scribtm1b(NCOM)Mfgc HET   Early adult 2.35×10-05
abnormal embryo size Scribtm1b(NCOM)Mfgc HOM E15.5 0.00
decreased lean body mass Scribtm1b(NCOM)Mfgc HET   Early adult 3.98×10-05
abnormal bone structure Scribtm1b(NCOM)Mfgc HET   Early adult 5.07×10-06
short tibia Scribtm1b(NCOM)Mfgc HET   Early adult 8.34×10-05
preweaning lethality, complete penetrance Scribtm1b(NCOM)Mfgc HOM   Early adult 0.00
embryonic growth retardation Scribtm1b(NCOM)Mfgc HOM E9.5 0.00
abnormal embryo size Scribtm1b(NCOM)Mfgc HOM E12.5 0.00
decreased bone mineral content Scribtm1b(NCOM)Mfgc HET   Early adult 9.94×10-05
abnormal neural tube closure Scribtm1b(NCOM)Mfgc HOM E12.5 0.00

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

No Adult expression data was found for this gene.
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
2  (1/64)  (2/2) N/A
2  (6/505)  (2/3) N/A
2  (1/73)  (2/2) N/A
2  (1/505)  (2/3) N/A
2  (1/506)  (2/3) N/A
2  (1/505)  (2/3) N/A
2  (1/505)  (2/3) N/A
2  (1/505)  (2/3) N/A
2  (1/505)  (2/3) N/A
2  (1/59)  (2/2) N/A
2  (1/505)  (2/3) N/A
2  (5/505)  (2/3) N/A
2  (1/505)  (2/3) N/A
2  (6/505)  (2/3) N/A
2  (1/505)  (2/3) N/A
2  (1/503)  (2/3) N/A
2  (1/503)  (2/3) N/A
2  (1/505)  (2/3) N/A
2  (1/505)  (2/3) N/A
2  (1/505)  (2/3) N/A
2  (1/75)  (2/2) N/A
2  (1/503)  (2/3) N/A
2  (1/75)  (2/2) N/A
2  (1/505)  (2/3) N/A
2  (1/72)  (2/2) N/A
2  (1/505)  (2/3) N/A
2  (1/505)  (2/3) N/A
2  (1/59)  (2/2) N/A
2  (1/59)  (2/2) N/A

 Associated Images

Eye Morphology: Images Ophthalmoscopy
13 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images
Immunophenotyping: Panel B FCS file(s)
3 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
Gross Morphology Embryo E9.5
6 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images
Embryo LacZ: LacZ images wholemount
12 Images
Gross Pathology and Tissue Collection
8 Images
Immunophenotyping: Panel A FCS file(s)
3 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Histopathology

 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Scribtm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Scribtm1a(NCOM)Mfgc KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Scribtm1b(NCOM)Mfgc Reporter-tagged deletion allele (post-Cre) Mice, Tissue

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