Gene: Scrib

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Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal lean body mass Scribtm1b(NCOM)Mfgc HET Early adult 3.98×10-05
abnormal embryo size Scribtm1b(NCOM)Mfgc HOM E12.5 0.00
abnormal bone structure Scribtm1b(NCOM)Mfgc HET Early adult 5.07×10-06
abnormal tibia morphology Scribtm1b(NCOM)Mfgc HET Early adult 8.34×10-05
abnormal placenta size Scribtm1b(NCOM)Mfgc HOM E12.5 0.00
abnormal bone mineralization Scribtm1b(NCOM)Mfgc HET Early adult 9.94×10-05
abnormal tail morphology Scribtm1b(NCOM)Mfgc HOM E15.5 0.00
abnormal craniofacial morphology Scribtm1b(NCOM)Mfgc HOM E15.5 0.00
abnormal grip strength Scribtm1b(NCOM)Mfgc HET Early adult 4.72×10-05
abnormal neural tube closure Scribtm1b(NCOM)Mfgc HOM E12.5 0.00
abnormal craniofacial morphology Scribtm1b(NCOM)Mfgc HOM E12.5 0.00
abnormal embryo size Scribtm1b(NCOM)Mfgc HOM E15.5 0.00
abnormal eye morphology Scribtm1b(NCOM)Mfgc HOM E12.5 0.00
preweaning lethality, complete penetrance Scribtm1b(NCOM)Mfgc HOM Early adult 0.00
abnormal forebrain morphology Scribtm1b(NCOM)Mfgc HOM E12.5 0.00
abnormal neural tube closure Scribtm1b(NCOM)Mfgc HOM E9.5 0.00
abnormal embryo size Scribtm1b(NCOM)Mfgc HOM E9.5 0.00
abnormal hindbrain morphology Scribtm1b(NCOM)Mfgc HOM E12.5 0.00
abnormal midbrain morphology Scribtm1b(NCOM)Mfgc HOM E12.5 0.00
abnormal limb morphology Scribtm1b(NCOM)Mfgc HOM E15.5 0.00
abnormal pericardium morphology Scribtm1b(NCOM)Mfgc HOM E12.5 0.00

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 Expression

IMPC lacZ Expression Data

No Adult expression data was found for this gene.
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2  (1/65)  (2/2) N/A
Brain 2  (6/506)  (2/3) N/A
Central nervous system ganglion 2  (1/74)  (2/2) N/A
Ear 2  (1/506)  (2/3) N/A
Embryo 2  (1/507)  (2/3) N/A
Eye 2  (1/506)  (2/3) N/A
Foot 2  (1/506)  (2/3) N/A
Forebrain 2  (1/506)  (2/3) N/A
Forelimb 2  (1/506)  (2/3) N/A
Gut 2  (1/60)  (2/2) N/A
Hand 2  (1/505)  (2/3) N/A
Head 2  (5/506)  (2/3) N/A
Heart 2  (1/506)  (2/3) N/A
Hindbrain 2  (6/506)  (2/3) N/A
Hindlimb 2  (1/505)  (2/3) N/A
Liver 2  (1/506)  (2/3) N/A
Lung 2  (1/502)  (2/3) N/A
Mandibular process 2  (1/506)  (2/3) N/A
Maxillary process 2  (1/506)  (2/3) N/A
Midbrain 2  (1/506)  (2/3) N/A
Nose 2  (1/74)  (2/2) N/A
Oral cavity 2  (1/506)  (2/3) N/A
Skeleton 2  (1/74)  (2/2) N/A
Skin 2  (1/506)  (2/3) N/A
Spinal cord 2  (1/73)  (2/2) N/A
Tail 2  (1/506)  (2/3) N/A
Tail somite 2  (1/506)  (2/3) N/A
Trachea 2  (1/60)  (2/2) N/A
Urinary system 2  (1/60)  (2/2) N/A

 Associated Images

X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images
Eye Morphology: Images Ophthalmoscopy
13 Images
Histopathology
3 Images
Embryo LacZ: LacZ images wholemount
12 Images
Immunophenotyping: Panel B FCS file(s)
3 Images
Immunophenotyping: Panel A FCS file(s)
3 Images
Gross Pathology and Tissue Collection
8 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Scribtm1b(NCOM)Mfgc Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Scribtm1a(NCOM)Mfgc KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Scribtm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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