Gene: Txndc5

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Name
thioredoxin domain containing 5
MGI ID
MGI:2145316
Synonyms
PC-TRP ERp46
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
enlarged heart Txndc5tm1.1(KOMP)Vlcg HET Early adult 0.00
abnormal locomotor activation Txndc5tm1.1(KOMP)Vlcg HOM Early adult 3.38×10-06
small testis Txndc5tm1.1(KOMP)Vlcg HOM Early adult 0.00
abnormal testis morphology Txndc5tm1.1(KOMP)Vlcg HET Early adult 0.00
abnormal testis morphology Txndc5tm1.1(KOMP)Vlcg HOM Early adult 0.00
abnormal seminal vesicle morphology Txndc5tm1.1(KOMP)Vlcg HET Early adult 0.00
abnormal heart morphology Txndc5tm1.1(KOMP)Vlcg HET Early adult 0.00
decreased circulating triglyceride level Txndc5tm1.1(KOMP)Vlcg HET Early adult 1.72×10-08
small testis Txndc5tm1.1(KOMP)Vlcg HET Early adult 0.00
small seminal vesicle Txndc5tm1.1(KOMP)Vlcg HET Early adult 0.00
abnormal prepulse inhibition Txndc5tm1.1(KOMP)Vlcg HOM Early adult 7.06×10-07
decreased circulating cholesterol level Txndc5tm1.1(KOMP)Vlcg HET Early adult 7.37×10-05

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (3/589) N/A
Aorta 2 No  (1/589) N/A
Blood 2 No N/A
Bone marrow 2 No  (1/2)  Section images
Brain 2 No  (3/589) N/A
Brainstem 2 No  (2/589) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cecum 2 No  (12/379)  (1/2)  Section images
Cerebellum 2 No  (3/589)  (1/2)  Section images
Cerebral cortex 2 No  (2/589) N/A
Chest bone 2 No N/A
Colon 2 No  (12/127)  (2/2)  Section images
Diaphragm 2 No N/A
Duodenum 2 No  (2/127)  (1/2)  Section images
Epididymis 2 No  (18/134)  (1/2)  Section images
Esophagus 2 No  (7/415) N/A
Eye 2 No  (1/2)  Section images
Gall bladder 2 No N/A
Gonadal fat pad 2 No N/A
Harderian gland 2 No N/A
Heart 2 No  (1/589) N/A
Hindlimb 2 No N/A
Hippocampus 2 No  (3/589) N/A
Hypothalamus 2 No  (2/589) N/A
Ileum 2 No  (14/127)  (1/2)  Section images
Jejunum 2 No  (6/127) N/A
Kidney 2 No  (20/589)  (1/2)  Section images
Large intestine 2 No  (10/589) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (1/589) N/A
Lung 2 No  (1/589)  (1/2)  Section images
Lymph node 2 No N/A
Mammary gland 2 No N/A
Mesenteric adipose tissue 2 No N/A
Mesenteric lymph node 2 No N/A
Midbrain 2 No  (2/2)  Section images
Olfactory lobe 2 No  (2/589) N/A
Ovary 2 No  (1/589) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/589) N/A
Parathyroid gland 2 No N/A
Parotid gland 2 No N/A
Penis 2 No  (1/2)  Section images
Peripheral nervous system 2 No  (1/589) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/589)  (2/2)  Section images
Prostate gland 2 No  (12/589) N/A
Quadriceps 2 No  (1/2)  Section images
Sciatic nerve 2 No N/A
Skeletal muscle 2 No N/A
Skin 2 No  (2/2)  Section images
Small intestine 2 No  (9/589) N/A
Spinal cord 2 No  (2/589) N/A
Spleen 2 No  (2/589)  (1/2)  Section images
Stomach 2 No  (13/589) N/A
Stomach pyloric region 2 No N/A
Striatum 2 No  (3/589) N/A
Sublingual gland 2 No N/A
Submandibular gland 2 No  (2/132) N/A
Testis 2 No  (5/589)  (1/2)  Section images
Thymus 2 No N/A
Thyroid gland 2 No  (16/589) N/A
Tongue 2 No  (5/127) N/A
Trachea 2 No  (2/589) N/A
Trigeminal V nerve 2 No N/A
Urinary bladder 2 No  (1/2)  Section images
Uterus 2 No N/A
Vagina 2 No N/A
Vas deferens 2 No  (15/388)  (1/2)  Section images
Vascular system 2 No N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No N/A
No Embryo expression data was found for this gene.

 Associated Images

Adult LacZ: LacZ Images Section
47 Images
X-ray: XRay Images Whole Body Lateral Orientation
20 Images
X-ray: XRay Images Whole Body Dorso Ventral
20 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Txndc5tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice, Tissue
Txndc5tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Txndc5tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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