Gene Summary
IMPC Data Collections
- Body Weight Measurements
- No Embryo Imaging Data
- Viability Data
An assay measuring the expression of lacZ shows the tissue where the gene is expressed.
Anatomy | Images | Zygosity | Mutant Expr |
---|---|---|---|
Kidney | Wholemount images | heterozygote | 100% (1 of 1) |
Liver | Wholemount images | heterozygote | 100% (1 of 1) |
Peripheral nervous system | Wholemount images | heterozygote | 0.0% (0 of 1) |
Adrenal gland | N/A | heterozygote | 100% (1 of 1) |
Aorta | N/A | heterozygote | 0.0% (0 of 1) |
Bone | N/A | heterozygote | 0.0% (0 of 1) |
Brain | N/A | heterozygote | 0.0% (0 of 1) |
Brainstem | N/A | heterozygote | 0.0% (0 of 1) |
Brown adipose tissue | N/A | heterozygote | 0.0% (0 of 1) |
Cartilage tissue | N/A | heterozygote | 0.0% (0 of 1) |
Cerebellum | N/A | heterozygote | 0.0% (0 of 1) |
Cerebral cortex | N/A | heterozygote | 0.0% (0 of 1) |
Esophagus | N/A | heterozygote | 0.0% (0 of 1) |
Eye | N/A | heterozygote | Not available |
Gall bladder | N/A | heterozygote | 0.0% (0 of 1) |
Heart | N/A | heterozygote | 0.0% (0 of 1) |
Hippocampus | N/A | heterozygote | 0.0% (0 of 1) |
Hypothalamus | N/A | heterozygote | 0.0% (0 of 1) |
Large intestine | N/A | heterozygote | 0.0% (0 of 1) |
Lower urinary tract | N/A | heterozygote | 0.0% (0 of 1) |
Lung | N/A | heterozygote | 0.0% (0 of 1) |
Lymph node | N/A | heterozygote | 0.0% (0 of 1) |
Mammary gland | N/A | heterozygote | Not available |
Mesenteric lymph node | N/A | heterozygote | 0.0% (0 of 1) |
Olfactory lobe | N/A | heterozygote | 0.0% (0 of 1) |
Oral epithelium | N/A | heterozygote | 0.0% (0 of 1) |
Ovary | N/A | heterozygote | Not available |
Oviduct | N/A | heterozygote | Not available |
Pancreas | N/A | heterozygote | 0.0% (0 of 1) |
Parathyroid gland | N/A | heterozygote | 0.0% (0 of 1) |
Peyer's patch | N/A | heterozygote | 0.0% (0 of 1) |
Pituitary gland | N/A | heterozygote | 0.0% (0 of 1) |
Prostate gland | N/A | heterozygote | Ambiguous |
Skeletal muscle | N/A | heterozygote | 0.0% (0 of 1) |
Skin | N/A | heterozygote | 0.0% (0 of 1) |
Small intestine | N/A | heterozygote | 0.0% (0 of 1) |
Spinal cord | N/A | heterozygote | 0.0% (0 of 1) |
Spleen | N/A | heterozygote | 0.0% (0 of 1) |
Stomach | N/A | heterozygote | 0.0% (0 of 1) |
Striatum | N/A | heterozygote | 0.0% (0 of 1) |
Testis | N/A | heterozygote | Ambiguous |
Thymus | N/A | heterozygote | 0.0% (0 of 1) |
Thyroid gland | N/A | heterozygote | 0.0% (0 of 1) |
Trachea | N/A | heterozygote | 0.0% (0 of 1) |
Trigeminal V nerve | N/A | heterozygote | 0.0% (0 of 1) |
Urinary bladder | N/A | heterozygote | 0.0% (0 of 1) |
Uterus | N/A | heterozygote | Not available |
Vas deferens | N/A | heterozygote | Ambiguous |
Vascular system | N/A | heterozygote | 0.0% (0 of 1) |
White adipose tissue | N/A | heterozygote | 0.0% (0 of 1) |
Background staining occurs in wild type mice and embryos at an incidental rate.
Anatomy | Background staining in controls (WT) |
---|---|
adrenal gland | 0.0% |
aorta | 0.0% |
bone | 0.0% |
brain | 0.0% |
brainstem | 0.0% |
brown adipose tissue | 0.0% |
cartilage tissue | 0.0% |
cerebellum | 0.0% |
cerebral cortex | 0.0% |
esophagus | 0.0% |
eye | 0.0% |
gall bladder | 0.0% |
heart | 0.0% |
hippocampus | 0.0% |
hypothalamus | 0.0% |
kidney | 0.0% |
large intestine | 0.0% |
liver | 0.0% |
lower urinary tract | 0.0% |
lung | 0.0% |
lymph node | 0.0% |
mammary gland | 0.0% |
mesenteric lymph node | |
olfactory lobe | 0.0% |
oral epithelium | 0.0% |
ovary | 0.0% |
oviduct | 0.0% |
pancreas | 0.0% |
parathyroid gland | 0.0% |
peripheral nervous system | 0.0% |
peyers patch | 0.0% |
pituitary gland | 0.0% |
prostate gland | 0.0% |
skeletal muscle | 0.0% |
skin | 0.0% |
small intestine | 0.0% |
spinal cord | 0.0% |
spleen | 0.0% |
stomach | 0.0% |
striatum | 0.0% |
testis | 0.0% |
thymus | 0.0% |
thyroid gland | 0.0% |
trachea | 0.0% |
trigeminal v nerve | 0.0% |
urinary bladder | |
uterus | 0.0% |
vas deferens | Unavailable |
vascular system | 0.0% |
white adipose tissue | 0.0% |
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Slc25a47.
There are 2 publications which use IMPC produced mice or data.
Title | Journal | IMPC Allele | PubMed ID |
---|---|---|---|
The SLC25A47 locus controls gluconeogenesis and energy expenditure. | Proceedings of the National Academy of Sciences of the United States of America (February 2023) | Slc25a47tm1c(EUCOMM)Hmgu Slc25a47tm1a(EUCOMM)Hmgu | PMC9992842 |
The Slc25a47 locus is a novel determinant of hepatic mitochondrial function implicated in liver fibrosis. | Journal of hepatology (June 2022) | Slc25a47tm1c(EUCOMM)Hmgu Slc25a47tm1a(EUCOMM)Hmgu | 35714811 |
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
MGI Allele | Allele Type | Produced |
---|---|---|
Slc25a47tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | Mice, Targeting vectors, ES Cells |
Slc25a47tm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | Mice |
Slc25a47tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | ES Cells |
Slc25a47tm1(KOMP)Mbp | Reporter-tagged deletion allele (with selection cassette) | Targeting vectors, ES Cells |
Slc25a47tm1(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | Targeting vectors, ES Cells |
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