Not currently registered for phenotyping at IMPC
Phenotyping is currently not planned for a knockout strain of this gene.
Gene Summary
IMPC Data Collections
- No Body Weight Data
- No Embryo Imaging Data
- No Viability Data
Phenotyping is currently not planned for a knockout strain of this gene.
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
The table below shows human diseases predicted to be associated to Zdhhc7 by phenotypic similarity.
Disease | Similarity of phenotypes |
Matching phenotypes | Source |
---|---|---|---|
Familial Alzheimer-Like Prion Disease | Emotional lability, Cognitive impairment, Anxiety, Attention deficit hyperactivity disorder, Defi... | ORPHA:280397 | |
Progressive Supranuclear Palsy | Unsteady gait, Falls, Cognitive impairment, Dementia, Memory impairment, Dysphagia, Abnormal syna... | ORPHA:683 | |
Epilepsy, Progressive Myoclonic, 12 | Difficulty walking, Ataxia, Anxiety, Attention deficit hyperactivity disorder, Mental deteriorati... | OMIM:619191 | |
Pandas | Emotional lability, Abnormal fear/anxiety-related behavior, Agoraphobia, Claustrophobia, Attentio... | ORPHA:66624 | |
Obsolete: Early-Onset Schizophrenia | Emotional lability, Polyphagia, Impairment in personality functioning, Suicidal ideation, Abnorma... | ORPHA:96369 |
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MGI Allele | Allele Type | Produced |
---|---|---|
Zdhhc7tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | Mice, ES Cells |
Zdhhc7tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | Targeting vectors, ES Cells |
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