Arhgef18 | Rho/Rac guanine nucleotide exchange factor 18
Physiological systems
20 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Homeostasis/metabolism Vision/eye Mortality/aging
17 No significant impact
4 Not tested
Gene metrics:4Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
42Embryo tissues
abnormal retina morphology | 1 supporting dataset | Arhgef18tm1b(KOMP)Mbp | heterozygote | Early adult | 1.15x10-16 | ||
preweaning lethality, complete penetrance | 1 supporting dataset | Arhgef18tm1b(KOMP)Mbp | homozygote | Early adult | N/A * | ||
increased circulating amylase level | 1 supporting dataset | Arhgef18tm1b(KOMP)Mbp | heterozygote | Early adult | 8.26x10-5 | ||
preweaning lethality, incomplete penetrance | 1 supporting dataset | Arhgef18Gt(EUC0027g03)Hmgu | homozygote | Early adult | N/A * |
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External links
No external links available for Arhgef18.
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Arhgef18tm1a(KOMP)Mbp | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
Arhgef18tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
Arhgef18tm1b(KOMP)Mbp | Reporter-tagged deletion allele (with selection cassette) | | mouse |
Arhgef18tm1e(KOMP)Mbp | Targeted, non-conditional allele | | ES Cell |
Arhgef18tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |