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Genes Phenotypes

Gene: Arhgef18

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Name
rho/rac guanine nucleotide exchange factor (GEF) 18
MGI ID
MGI:2142567
Synonyms
D030053O22Rik A430078G23Rik
Viability
Homozygous - Lethal
Embryo viewer
3D Imaging
Other links
MGI   Ensembl  
Significant phenotypes (3) Measurements chart (298) All data table (811)
Expression & images (21) Disease models (0) Order (2)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal retina morphology Arhgef18tm1b(KOMP)Mbp HET Early adult 1.14×10-16
increased basophil cell number Arhgef18tm1b(KOMP)Mbp HET Early adult 9.13×10-05
preweaning lethality, complete penetrance Arhgef18tm1b(KOMP)Mbp HOM Early adult 0.00

Download data as:  TSV  XLS

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Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

No Adult expression data was found for this gene.
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 1  (6/506) Image Only N/A
Ear 1  (1/506) Image Only N/A
Embryo 1  (1/507) Image Only N/A
Eye 1  (1/506) Image Only N/A
Foot 1  (1/506) Image Only N/A
Forebrain 1  (1/506) Image Only N/A
Forelimb 1  (1/506) Image Only N/A
Hand 1  (1/506) Image Only N/A
Head 1  (5/506) Image Only N/A
Heart 1  (1/506) Image Only N/A
Hindbrain 1  (6/506) Image Only N/A
Hindlimb 1  (1/506) Image Only N/A
Liver 1  (1/504) Image Only N/A
Lung 1  (1/504) Image Only N/A
Mandibular process 1  (1/506) Image Only N/A
Maxillary process 1  (1/506) Image Only N/A
Midbrain 1  (1/506) Image Only N/A
Oral cavity 1  (1/504) Image Only N/A
Skin 1  (1/506) Image Only N/A
Tail 1  (1/506) Image Only N/A
Tail somite 1  (1/506) Image Only N/A

 Associated Images

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X-ray: XRay Images Whole Body Lateral Orientation
10 Images
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Embryo LacZ: LacZ images wholemount
8 Images
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X-ray: XRay Images Whole Body Dorso Ventral
10 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Arhgef18tm1b(KOMP)Mbp Reporter-tagged deletion allele (post-Cre) Mice
Arhgef18tm1a(KOMP)Mbp KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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