Gene: Unc45a

Name
unc-45 myosin chaperone A
MGI ID
MGI:2142246
Synonyms
N/A
Viability
Homozygous - Lethal
Other links
View data by physiological system
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
increased hematocrit Unc45atm1b(EUCOMM)Hmgu HET postnatal 3.22×10-05
preweaning lethality, complete penetrance Unc45atm1b(EUCOMM)Hmgu HOM n/a 0.000317
prolonged RR interval Unc45atm1b(EUCOMM)Hmgu HET postnatal 5.28×10-05
abnormal lens morphology Unc45atm1b(EUCOMM)Hmgu HET postnatal 2.15×10-06
increased erythrocyte cell number Unc45atm1b(EUCOMM)Hmgu HET postnatal 4.40×10-05
decreased heart rate Unc45atm1b(EUCOMM)Hmgu HET postnatal 5.51×10-05

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Filtered by: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Blood 2 No N/A
Bone 2 No N/A
Bone marrow 2 No N/A
Brain 2 No  (2/2)  Wholemount images
Brainstem 2 No N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cecum 2 No  (12/383)  (2/2)  Wholemount images
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Chest bone 2 No  (2/2)  Wholemount images
Colon 2 No  (12/127) N/A
Cranium 2 No N/A
Diaphragm 2 No N/A
Epididymis 2 No  (18/134) N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Harderian gland 2 No N/A
Heart 2 No N/A
Hindlimb 2 No N/A
Hippocampus 2 No N/A
Hypothalamus 2 No  (1/2)  Wholemount images
Kidney 2 No  (18/584)  (2/2)  Wholemount images
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No N/A
Lymph node 2 No N/A
Main olfactory bulb 2 No N/A
Mammary gland 2 No N/A
Mesenteric lymph node 2 No N/A
Olfactory lobe 2 No N/A
Oral epithelium 2 No N/A
Ovary 2 No  (1/584) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/584) N/A
Parathyroid gland 2 No N/A
Parotid gland 2 No N/A
Penis 2 No  (1/2)  Wholemount images
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/2)  Wholemount images
Prostate gland 2 No  (12/584) N/A
Sciatic nerve 2 No N/A
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584)  (2/2)  Wholemount images
Spinal cord 2 No N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584)  (2/2)  Wholemount images
Stomach pyloric region 2 No N/A
Striatum 2 No N/A
Sublingual gland 2 No N/A
Submandibular gland 2 No  (2/132)  (1/2)  Wholemount images
Testis 2 No  (2/584)  (1/2)  Wholemount images
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Tongue 2 No  (5/127) N/A
Trachea 2 No  (2/2)  Wholemount images
Trigeminal V nerve 2 No N/A
Urinary bladder 2 No  (1/2)  Wholemount images
Uterus 2 No  (1/2)  Wholemount images
Vagina 2 No N/A
Vas deferens 2 No  (15/388) N/A
Vascular system 2 No N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No N/A
No Embryo expression data was found for this gene.

 Associated Images

Adult LacZ: LacZ Images Wholemount
21 Images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Unc45atm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Unc45atm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice

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