Lrrk1 | leucine-rich repeat kinase 1
Physiological systems
20 / 24 physiological systems tested
10 Significantly impacted by the knock-out
Vision/eye Behavior/neurological Limbs/digits/tail Immune system Homeostasis/metabolism Adipose tissue Skeleton Hematopoietic system Craniofacial Growth/size/body region
10 No significant impact
4 Not tested
Data collections
Gene metrics:40Significant phenotypes
2Associated diseases
Expression examined in:46Adult tissues
0Embryo tissues
Human diseases caused by Lrrk1 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
Loading...