Prkd2 | protein kinase D2

GeneMGI:2141917Synonyms: PKD2

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Nervous system Vision/eye Behavior/neurological

16 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased prepulse inhibition4 supporting datasetsPrkd2em1(IMPC)HmguhomozygoteEarly adult1.18x10-11 
increased circulating alanine transaminase level1 supporting datasetPrkd2em1(IMPC)HmguhomozygoteEarly adult1.56x10-5 
abnormal brain morphology1 supporting datasetPrkd2em1(IMPC)HmguhomozygoteEarly adultN/A * 
persistence of hyaloid vascular system1 supporting datasetPrkd2em1(IMPC)HmguhomozygoteEarly adult4.52x10-6 
decreased food intake1 supporting datasetPrkd2em1(IMPC)HmguhomozygoteEarly adult2.59x10-5 
decreased respiratory quotient1 supporting datasetPrkd2em1(IMPC)HmguhomozygoteEarly adult2.71x10-5 
decreased startle reflex1 supporting datasetPrkd2em1(IMPC)HmguhomozygoteEarly adult2.22x10-18 
* Does not have a P-value assigned because it was manually marked as significant.
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* Does not have a P-value assigned because it was manually marked as significant.
Download data as:  

lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Prkd2em1(IMPC)HmguIntra-exon deletionmouse
Prkd2tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell

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