Gene: Vopp1

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Name
vesicular, overexpressed in cancer, prosurvival protein 1
MGI ID
MGI:2141658
Synonyms
N/A
Viability
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
decreased grip strength Vopp1em1(IMPC)J HOM Early adult 7.49×10-05
abnormal startle reflex Vopp1em1(IMPC)J HOM Late adult 1.63×10-06
impaired pupillary reflex Vopp1em1(IMPC)J HOM Early adult 1.76×10-12

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (4/584)  (2/2)  Section images
Aorta 2 No  (1/584)  (2/2)  Section images
Brain 2 No  (4/584)  (2/2)  Section images
Brainstem 2 No  (2/584)  (2/2)  Section images
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (1/584)  (2/2)  Section images
Cerebellum 2 No  (3/584)  (2/2)  Section images
Cerebral cortex 2 No  (2/584)  (2/2)  Section images
Epididymis 2 No  (17/133)  (1/2)  Section images
Esophagus 2 No  (7/408)  (2/2)  Section images
Eye 2 No  (2/2)  Section images
Heart 2 No  (2/584)  (2/2)  Section images
Hippocampus 2 No  (3/584)  (2/2)  Section images
Hypothalamus 2 No  (2/584)  (2/2)  Section images
Kidney 2 No  (21/584)  (2/2)  Section images
Large intestine 2 No  (10/584)  (2/2)  Section images
Liver 2 No N/A
Lower urinary tract 2 No  (1/584) N/A
Lung 2 No  (2/584)  (2/2)  Section images
Lymph node 2 No  (1/584) N/A
Mammary gland 2 No N/A
Midbrain 2 No  (2/2)  Section images
Olfactory lobe 2 No  (2/584)  (2/2)  Section images
Ovary 2 No  (1/584)  (1/2)  Section images
Oviduct 2 No  (1/2)  Section images
Pancreas 2 No  (5/584) N/A
Peripheral nervous system 2 No  (2/584) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/584)  (2/2)  Section images
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (1/584)  (2/2)  Section images
Small intestine 2 No  (9/584)  (2/2)  Section images
Spinal cord 2 No  (3/584)  (2/2)  Section images
Spleen 2 No  (3/584) N/A
Stomach 2 No  (12/584)  (2/2)  Section images
Striatum 2 No  (3/584)  (2/2)  Section images
Submandibular gland 2 No  (2/131)  (2/2)  Section images
Testis 2 No  (6/584)  (1/2)  Section images
Thalamus 2 No  (2/2)  Section images
Thymus 2 No  (1/584)  (2/2)  Section images
Thyroid gland 2 No  (16/584) N/A
Trachea 2 No  (3/584)  (2/2)  Section images
Urinary bladder 2 No  (2/2)  Section images
Uterus 2 No  (1/2)  Section images
Vascular system 2 No  (2/2)  Section images
Vesicular gland 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/507)  (2/2) N/A
Dorsal root ganglion 2  (1/59) Image Only N/A
Ear 2  (1/507)  (1/2) N/A
Embryo 2  (1/508)  (2/2)  Wholemount images
Eye 2  (1/507)  (2/2) N/A
Footplate 2  (1/507)  (2/2) N/A
Forebrain 2  (1/507)  (2/2) N/A
Forelimb 2  (1/507)  (2/2) N/A
Fronto-nasal process 2  (1/60) Image Only N/A
Handplate 2  (1/507)  (2/2) N/A
Head 2  (5/507)  (2/2) N/A
Heart 2  (1/507)  (2/2) N/A
Hindbrain 2  (6/507)  (2/2) N/A
Hindlimb 2  (1/507)  (2/2) N/A
Liver 2  (1/502) N/A
Lung 2  (1/502) Image Only N/A
Mandibular process 2  (1/507)  (2/2) N/A
Maxillary process 2  (1/507)  (2/2) N/A
Midbrain 2  (1/507)  (2/2) N/A
Nose 2  (1/77)  (2/2) N/A
Oral cavity 2  (1/502) Image Only N/A
Skin 2  (1/507)  (2/2) N/A
Spinal cord 2  (1/71)  (2/2) N/A
Tail 2  (1/507)  (2/2) N/A
Tail somite group 2  (1/507)  (2/2) N/A

 Associated Images

Original Image
Adult LacZ: LacZ Images Section
34 Images
X-ray: XRay Images Skull Lateral Orientation
11 Images
Embryo LacZ: LacZ images wholemount
8 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
11 Images
X-ray: XRay Images Whole Body Lateral Orientation
11 Images
X-ray: XRay Images Whole Body Dorso Ventral
11 Images
X-ray: XRay Images Forepaw
11 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
12 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Vopp1tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Vopp1tm1a(KOMP)Mbp KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Vopp1tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Vopp1em1(IMPC)J Intra-exon deletion Mice

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