Gene Summary
IMPC Data Collections
- Body Weight Measurements
- No Embryo Imaging Data
- Viability Data
The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.
An assay measuring the expression of lacZ shows the tissue where the gene is expressed.
Anatomy | Images | Zygosity | Mutant Expr |
---|---|---|---|
Brain | N/A | heterozygote | Ambiguous |
Central nervous system ganglion | N/A | heterozygote | Ambiguous |
Cranium | N/A | heterozygote | Ambiguous |
Ear | N/A | heterozygote | Ambiguous |
Embryo | N/A | heterozygote | Ambiguous |
Outer ear | N/A | heterozygote | Ambiguous |
Eye | N/A | heterozygote | Ambiguous |
Footplate | N/A | heterozygote | Ambiguous |
Forearm | N/A | heterozygote | Ambiguous |
Forebrain | N/A | heterozygote | Ambiguous |
Forelimb | N/A | heterozygote | Ambiguous |
Handplate | N/A | heterozygote | Ambiguous |
Head | N/A | heterozygote | Ambiguous |
Heart | N/A | heterozygote | Ambiguous |
Hindbrain | N/A | heterozygote | Ambiguous |
Hindlimb | N/A | heterozygote | Ambiguous |
Humerus pre-cartilage condensation | N/A | heterozygote | Ambiguous |
Inner ear | N/A | heterozygote | Ambiguous |
Liver | N/A | heterozygote | Ambiguous |
Lower leg | N/A | heterozygote | Ambiguous |
Lung | N/A | heterozygote | Ambiguous |
Mandibular process | N/A | heterozygote | Ambiguous |
Maxillary process | N/A | heterozygote | Ambiguous |
Midbrain | N/A | heterozygote | Ambiguous |
Nose | N/A | heterozygote | Ambiguous |
Oral cavity | N/A | heterozygote | Ambiguous |
Chorioallantoic placenta | N/A | heterozygote | Ambiguous |
Radius-ulna pre-cartilage condensation | N/A | heterozygote | Ambiguous |
Skeleton | N/A | heterozygote | Ambiguous |
Skin | N/A | heterozygote | Ambiguous |
Spinal cord | N/A | heterozygote | Ambiguous |
Tail somite | N/A | heterozygote | Ambiguous |
Tail | N/A | heterozygote | Ambiguous |
Upper arm | N/A | heterozygote | Ambiguous |
Upper leg | N/A | heterozygote | Ambiguous |
Vibrissa | N/A | heterozygote | Ambiguous |
Background staining occurs in wild type mice and embryos at an incidental rate.
Anatomy | Background staining in controls (WT) |
---|
Background staining occurs in wild type mice and embryos at an incidental rate.
Background staining occurs in wild type embryos at a measurable rate.
Anatomy | Background staining in controls(WT) |
---|---|
brain | 0.0% |
central nervous system ganglion | Ambiguous |
cranium | Ambiguous |
ear | 0.0% |
embryo | 0.0% |
external ear | Ambiguous |
eye | 0.0% |
footplate | 0.0% |
forearm | Ambiguous |
forebrain | 0.0% |
forelimb | 0.0% |
handplate | 0.0% |
head | 0.0% |
heart | 0.0% |
hindbrain | 0.0% |
hindlimb | 0.0% |
humerus pre-cartilage condensation | Ambiguous |
inner ear | Ambiguous |
liver | 0.0% |
lower leg | Ambiguous |
lung | 0.0% |
mandibular process | 0.0% |
maxillary process | 0.0% |
midbrain | 0.0% |
nose | Ambiguous |
oral cavity | 0.0% |
placenta | Ambiguous |
radius-ulna pre cartilage condensation | Ambiguous |
skeleton | Ambiguous |
skin | 0.0% |
spinal cord | Ambiguous |
tail | 0.0% |
tail somite group | 0.0% |
upper arm | Ambiguous |
upper leg | Ambiguous |
vibrissa | Ambiguous |
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
MGI Allele | Allele Type | Produced |
---|---|---|
Hepacam2tm1(KOMP)Mbp | Reporter-tagged deletion allele (with selection cassette) | Targeting vectors, ES Cells |
Hepacam2tm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | Mice |
Hepacam2tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | Mice, Targeting vectors, ES Cells |
Get highlights of the most important data releases, news and events, delivered straight to your email inbox
Subscribe to newsletter