Kctd10 | potassium channel tetramerisation domain containing 10

GeneMGI:2141207

Physiological systems

19 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Limbs/digits/tail Behavior/neurological Skeleton Mortality/aging

14 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:7Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



abnormal radius morphology	1 supporting dataset	Kctd10^{Gt(RRG305)Byg}	heterozygote	Early adult	1.44x10^-8
abnormal joint morphology	1 supporting dataset	Kctd10^{Gt(RRG305)Byg}	heterozygote	Early adult	6.25x10^-7
trunk curl	1 supporting dataset	Kctd10^{Gt(RRG305)Byg}	heterozygote	Early adult	2.23x10^-5
preweaning lethality, complete penetrance	1 supporting dataset	Kctd10^{Gt(RRG305)Byg}	homozygote	Early adult	N/A ^*
decreased circulating chloride level	1 supporting dataset	Kctd10^{Gt(RRG305)Byg}	heterozygote	Early adult	5.19x10^-5
decreased circulating sodium level	1 supporting dataset	Kctd10^{Gt(RRG305)Byg}	heterozygote	Early adult	4.21x10^-5
decreased grip strength	2 supporting datasets	Kctd10^{Gt(RRG305)Byg}	heterozygote	Early adult	2.13x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Kctd10.

Associated images

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Histopathology

There is no histopathology data found for Kctd10.

IMPC related publications

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External links

No external links available for Kctd10.

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*Kctd10^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Kctd10^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

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