Gene: Ttc28

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Name
tetratricopeptide repeat domain 28
MGI ID
MGI:2140873
Synonyms
2310015L07Rik TPRBK
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
decreased startle reflex Ttc28tm1b(EUCOMM)Hmgu HOM Early adult 1.21×10-08
decreased bone mineral density Ttc28tm1b(EUCOMM)Hmgu HOM Early adult 1.37×10-14
decreased bone mineral content Ttc28tm1b(EUCOMM)Hmgu HOM Early adult 3.37×10-14
abnormal cranium morphology Ttc28tm1b(EUCOMM)Hmgu HOM Early adult 7.41×10-12
increased heart weight Ttc28tm1b(EUCOMM)Hmgu HOM Early adult 6.12×10-06
short tibia Ttc28tm1b(EUCOMM)Hmgu HOM Early adult 2.01×10-14
abnormal bone structure Ttc28tm1b(EUCOMM)Hmgu HOM Early adult 1.07×10-12
abnormal vertebrae morphology Ttc28tm1b(EUCOMM)Hmgu HOM Early adult 2.24×10-12
vertebral fusion Ttc28tm1b(EUCOMM)Hmgu HOM Early adult 2.24×10-12
abnormal maxilla morphology Ttc28tm1b(EUCOMM)Hmgu HOM Early adult 9.26×10-13
abnormal zygomatic bone morphology Ttc28tm1b(EUCOMM)Hmgu HOM Early adult 2.24×10-12
increased leukocyte cell number Ttc28tm1b(EUCOMM)Hmgu HOM Early adult 2.98×10-05
decreased total body fat amount Ttc28tm1b(EUCOMM)Hmgu HOM Early adult 1.17×10-08
decreased lean body mass Ttc28tm1b(EUCOMM)Hmgu HOM Early adult 2.02×10-13
decreased circulating HDL cholesterol level Ttc28tm1b(EUCOMM)Hmgu HOM Early adult 2.07×10-15
decreased circulating cholesterol level Ttc28tm1b(EUCOMM)Hmgu HOM Early adult 1.71×10-13
increased circulating alkaline phosphatase level Ttc28tm1b(EUCOMM)Hmgu HOM Early adult 2.53×10-12
increased grip strength Ttc28tm1b(EUCOMM)Hmgu HOM Early adult 9.11×10-17
decreased circulating glucose level Ttc28tm1b(EUCOMM)Hmgu HOM Early adult 3.87×10-06
decreased body length Ttc28tm1b(EUCOMM)Hmgu HOM Early adult 2.27×10-09
decreased prepulse inhibition Ttc28tm1b(EUCOMM)Hmgu HOM Early adult 5.48×10-05
abnormal pelvic girdle bone morphology Ttc28tm1b(EUCOMM)Hmgu HOM Early adult 2.69×10-10

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 Expression

Expression data not available

 Associated Images

Gross Pathology and Tissue Collection
8 Images
Histopathology
6 Images
X-ray: XRay Images Whole Body Lateral Orientation
14 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
14 Images
X-ray: XRay Images Whole Body Dorso Ventral
14 Images
X-ray: XRay Images Skull Lateral Orientation
14 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Histopathology

Phenotype Allele Zygosity Sex Life Stage
Sternum - developmental and structural abnormality Ttc28tm1b(EUCOMM)Hmgu HOM Early adult
Knee joint - developmental and structural abnormality Ttc28tm1b(EUCOMM)Hmgu HOM Early adult

 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Ttc28tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Ttc28tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice, Tissue

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