Genes Phenotypes

Gene: Ttc28

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Name
tetratricopeptide repeat domain 28
MGI ID
MGI:2140873
Synonyms
2310015L07Rik TPRBK
Viability
Homozygous - Viable
View
N/A
Other links
MGI   Ensembl  
Significant phenotypes (20) Measurements chart (222) All data table (327)
Expression & images (0) Disease models (0) Histopathology (2) Order (2)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
decreased total body fat amount Ttc28tm1b(EUCOMM)Hmgu HOM postnatal 1.17×10-08
abnormal pelvic girdle bone morphology Ttc28tm1b(EUCOMM)Hmgu HOM postnatal 2.69×10-10
decreased circulating HDL cholesterol level Ttc28tm1b(EUCOMM)Hmgu HOM postnatal 2.65×10-15
abnormal maxilla morphology Ttc28tm1b(EUCOMM)Hmgu HOM postnatal 9.26×10-13
increased circulating alkaline phosphatase level Ttc28tm1b(EUCOMM)Hmgu HOM postnatal 1.28×10-05
decreased body length Ttc28tm1b(EUCOMM)Hmgu HOM postnatal 2.27×10-09
vertebral fusion Ttc28tm1b(EUCOMM)Hmgu HOM postnatal 2.24×10-12
decreased lean body mass Ttc28tm1b(EUCOMM)Hmgu HOM postnatal 2.02×10-13
increased grip strength Ttc28tm1b(EUCOMM)Hmgu HOM postnatal 4.58×10-15
decreased startle reflex Ttc28tm1b(EUCOMM)Hmgu HOM postnatal 2.45×10-08
short tibia Ttc28tm1b(EUCOMM)Hmgu HOM postnatal 2.01×10-14
abnormal bone structure Ttc28tm1b(EUCOMM)Hmgu HOM postnatal 1.07×10-12
abnormal vertebrae morphology Ttc28tm1b(EUCOMM)Hmgu HOM postnatal 2.24×10-12
abnormal cranium morphology Ttc28tm1b(EUCOMM)Hmgu HOM postnatal 7.41×10-12
increased red blood cell distribution width Ttc28tm1b(EUCOMM)Hmgu HOM postnatal 7.79×10-05
decreased circulating glucose level Ttc28tm1b(EUCOMM)Hmgu HOM postnatal 1.88×10-06
decreased bone mineral density Ttc28tm1b(EUCOMM)Hmgu HOM postnatal 1.37×10-14
decreased circulating cholesterol level Ttc28tm1b(EUCOMM)Hmgu HOM postnatal 2.35×10-14
decreased bone mineral content Ttc28tm1b(EUCOMM)Hmgu HOM postnatal 3.37×10-14
abnormal zygomatic bone morphology Ttc28tm1b(EUCOMM)Hmgu HOM postnatal 2.24×10-12

Download data as:  TSV  XLS

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Viewing: all phenotypes

 Expression

Expression data not available

 Associated Images

X-ray: XRay Images Skull Dorso Ventral Orientation
14 Images
Gross Pathology and Tissue Collection
8 Images
Histopathology
6 Images
X-ray: XRay Images Dorso Ventral
14 Images
X-ray: XRay Images Skull Lateral Orientation
14 Images
X-ray: XRay Images Lateral Orientation
14 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Histopathology

Phenotype Allele Zygosity Sex Life Stage
Sternum - developmental and structural abnormality Ttc28tm1b(EUCOMM)Hmgu HOM postnatal
Knee joint - developmental and structural abnormality Ttc28tm1b(EUCOMM)Hmgu HOM postnatal

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Ttc28tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Ttc28tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice, Tissue

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