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Genes Phenotypes Help, News, Blog

Gene: Ttc28

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Name
tetratricopeptide repeat domain 28
MGI ID
MGI:2140873
Synonyms
2310015L07Rik TPRBK
Viability
Data available
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (23) Measurements chart (204) All data table (605)
Expression & images (0) Disease models (0) Histopathology (2) Order (2)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
increased grip strength Ttc28tm1b(EUCOMM)Hmgu HOM Early adult 8.99×10-15
decreased circulating glucose level Ttc28tm1b(EUCOMM)Hmgu HOM Early adult 1.12×10-06
decreased circulating cholesterol level Ttc28tm1b(EUCOMM)Hmgu HOM Early adult 4.98×10-12
short tibia Ttc28tm1b(EUCOMM)Hmgu HOM Early adult 1.56×10-12
decreased bone mineral density Ttc28tm1b(EUCOMM)Hmgu HOM Early adult 3.63×10-05
decreased total body fat amount Ttc28tm1b(EUCOMM)Hmgu HOM   Early adult 3.18×10-05
vertebral fusion Ttc28tm1b(EUCOMM)Hmgu HOM Early adult 2.24×10-12
increased heart weight Ttc28tm1b(EUCOMM)Hmgu HOM Early adult 2.51×10-06
decreased circulating triglyceride level Ttc28tm1b(EUCOMM)Hmgu HOM Early adult 2.52×10-05
abnormal vertebrae morphology Ttc28tm1b(EUCOMM)Hmgu HOM Early adult 2.24×10-12
abnormal cranium morphology Ttc28tm1b(EUCOMM)Hmgu HOM Early adult 7.41×10-12
increased circulating alkaline phosphatase level Ttc28tm1b(EUCOMM)Hmgu HOM Early adult 9.54×10-07
decreased startle reflex Ttc28tm1b(EUCOMM)Hmgu HOM Early adult 2.94×10-20
preweaning lethality, incomplete penetrance Ttc28tm1b(EUCOMM)Hmgu HOM   Early adult 0.00
abnormal pelvic girdle bone morphology Ttc28tm1b(EUCOMM)Hmgu HOM Early adult 2.69×10-10
decreased circulating HDL cholesterol level Ttc28tm1b(EUCOMM)Hmgu HOM Early adult 1.29×10-14
increased red blood cell distribution width Ttc28tm1b(EUCOMM)Hmgu HOM Early adult 6.31×10-06
increased neutrophil cell number Ttc28tm1b(EUCOMM)Hmgu HOM Early adult 6.90×10-05
decreased body length Ttc28tm1b(EUCOMM)Hmgu HOM Early adult 8.74×10-10
increased lymphocyte cell number Ttc28tm1b(EUCOMM)Hmgu HOM Early adult 8.01×10-07
abnormal maxilla morphology Ttc28tm1b(EUCOMM)Hmgu HOM Early adult 9.26×10-13
abnormal zygomatic bone morphology Ttc28tm1b(EUCOMM)Hmgu HOM Early adult 2.24×10-12
increased leukocyte cell number Ttc28tm1b(EUCOMM)Hmgu HOM Early adult 1.60×10-07

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Viewing: all phenotypes

 Expression

Expression data not available

 Associated Images

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X-ray: XRay Images Skull Lateral Orientation
14 Images
Immunophenotyping: Panel A FCS file(s)
5 Images
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X-ray: XRay Images Whole Body Lateral Orientation
14 Images
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X-ray: XRay Images Whole Body Dorso Ventral
14 Images
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Gross Pathology and Tissue Collection
8 Images
Immunophenotyping: Panel B FCS file(s)
5 Images
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Histopathology
6 Images
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X-ray: XRay Images Skull Dorso Ventral Orientation
14 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Histopathology

Phenotype Allele Zygosity Sex Life Stage
Knee joint - developmental and structural abnormality Ttc28tm1b(EUCOMM)Hmgu HOM Early adult
Sternum - developmental and structural abnormality Ttc28tm1b(EUCOMM)Hmgu HOM Early adult

 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Ttc28tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Ttc28tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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