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Genes Phenotypes Help, News, Blog

Gene: Ttc28

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Name
tetratricopeptide repeat domain 28
MGI ID
MGI:2140873
Synonyms
2310015L07Rik TPRBK
Viability
Data available
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (20) Measurements chart (222) All data table (647)
Expression & images (0) Disease models (0) Histopathology (4) Order (2)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
increased leukocyte cell number Ttc28tm1b(EUCOMM)Hmgu HOM Early adult 1.56×10-06
increased grip strength Ttc28tm1b(EUCOMM)Hmgu HOM Early adult 2.67×10-12
short tibia Ttc28tm1b(EUCOMM)Hmgu HOM Early adult 1.56×10-12
abnormal vertebrae morphology Ttc28tm1b(EUCOMM)Hmgu HOM Early adult 2.24×10-12
decreased circulating cholesterol level Ttc28tm1b(EUCOMM)Hmgu HOM Early adult 4.39×10-09
increased circulating alkaline phosphatase level Ttc28tm1b(EUCOMM)Hmgu HOM Early adult 5.79×10-06
abnormal zygomatic bone morphology Ttc28tm1b(EUCOMM)Hmgu HOM Early adult 2.24×10-12
decreased body length Ttc28tm1b(EUCOMM)Hmgu HOM Early adult 8.74×10-10
increased lymphocyte cell number Ttc28tm1b(EUCOMM)Hmgu HOM Early adult 6.30×10-07
abnormal maxilla morphology Ttc28tm1b(EUCOMM)Hmgu HOM Early adult 9.26×10-13
vertebral fusion Ttc28tm1b(EUCOMM)Hmgu HOM Early adult 2.24×10-12
increased heart weight Ttc28tm1b(EUCOMM)Hmgu HOM Early adult 6.50×10-06
decreased bone mineral density Ttc28tm1b(EUCOMM)Hmgu HOM Early adult 3.63×10-05
preweaning lethality, incomplete penetrance Ttc28tm1b(EUCOMM)Hmgu HOM   Early adult 0.00
increased red blood cell distribution width Ttc28tm1b(EUCOMM)Hmgu HOM Early adult 4.88×10-14
decreased circulating HDL cholesterol level Ttc28tm1b(EUCOMM)Hmgu HOM Early adult 2.74×10-12
abnormal cranium morphology Ttc28tm1b(EUCOMM)Hmgu HOM Early adult 7.41×10-12
decreased prepulse inhibition Ttc28tm1b(EUCOMM)Hmgu HOM Early adult 5.66×10-06
increased neutrophil cell number Ttc28tm1b(EUCOMM)Hmgu HOM   Early adult 2.57×10-05
abnormal pelvic girdle bone morphology Ttc28tm1b(EUCOMM)Hmgu HOM Early adult 2.69×10-10

Download data as:  TSV  XLS

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Viewing: all phenotypes
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Viewing: all phenotypes

 Expression

Expression data not available

 Associated Images

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X-ray: XRay Images Whole Body Lateral Orientation
14 Images
Immunophenotyping: Panel B FCS file(s)
5 Images
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X-ray: XRay Images Hind Leg and Hip
11 Images
Immunophenotyping: Panel A FCS file(s)
5 Images
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X-ray: XRay Images Whole Body Dorso Ventral
14 Images
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Gross Pathology and Tissue Collection
8 Images
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X-ray: XRay Images Skull Lateral Orientation
16 Images
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X-ray: XRay Images Skull Dorso Ventral Orientation
16 Images
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Histopathology
6 Images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Histopathology

Phenotype Allele Zygosity Sex Life Stage
Sternum - MPATH pathological process term hyperplasia Ttc28tm1b(EUCOMM)Hmgu HOM Early adult
Knee joint - MPATH pathological process term developmental dysplasia Ttc28tm1b(EUCOMM)Hmgu HOM Early adult
Knee joint - MPATH pathological process term neoplasia Ttc28tm1b(EUCOMM)Hmgu HOM Early adult
Sternum - MPATH pathological process term fibro-osseous lesion Ttc28tm1b(EUCOMM)Hmgu HOM Early adult

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MGI Allele Allele Type Produced
Ttc28tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Ttc28tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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