Not currently registered for phenotyping at IMPC

Phenotyping is currently not planned for a knockout strain of this gene.

Gene Summary

Name:
calmodulin binding transcription activator 1
Synonyms:
1810059M14Rik,  2310058O09Rik

IMPC Data Collections

  • No Body Weight Data
  • No Embryo Imaging Data
  • No Viability Data

IMPC Phenotype Summary

Significant
Not Significant
Not tested

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Phenotype associated images not available

Human diseases caused by Camta1 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

The table below shows human diseases associated to Camta1 by orthology or direct annotation.

Disease Similarity of
phenotypes
Matching phenotypes Source
Non-Progressive Cerebellar Ataxia With Intellectual Disability
Ataxia, Dysmetria, Intention tremor, Abnormal pyramidal sign, Nonprogressive cerebellar ataxia, U... ORPHA:314647
Cerebellar Dysfunction With Variable Cognitive And Behavioral Abnormalities
Broad-based gait, Motor stereotypy, Ataxia, Poor gross motor coordination, Dysmetria, Hand tremor... OMIM:614756

The table below shows human diseases predicted to be associated to Camta1 by phenotypic similarity.

Disease Similarity of
phenotypes
Matching phenotypes Source
Neuropathy, Hereditary Sensory, Atypical
Ataxia, Babinski sign, Sensory ataxia OMIM:256860
Spinocerebellar Ataxia Type 23
Progressive cerebellar ataxia, Dysmetria, Limb ataxia, Babinski sign, Impaired distal vibration s... ORPHA:101108
Dystonia 31
Difficulty walking, Parkinsonism, Abnormal posturing OMIM:619565
Myoclonus, Familial, 1
Frequent falls, Ataxia, Falls, Myoclonus OMIM:614937
Spinocerebellar Ataxia Type 15/16
Ataxia, Action tremor, Tremor by anatomical site, Head tremor, Upper limb postural tremor, Gait a... ORPHA:98769
Huntington Disease-Like 1
Clumsiness, Bradykinesia, Poor fine motor coordination, Dysmetria, Simultanapraxia, Chorea, Gait ... ORPHA:157941
Lichtenstein-Knorr Syndrome
Ataxia, Action tremor, Dysmetria, Limb ataxia, Dysdiadochokinesis, Gait ataxia OMIM:616291
Spastic Ataxia 2, Autosomal Recessive
Dysmetria, Babinski sign, Head titubation, Frequent falls, Tremor, Gait ataxia, Spasticity, Fasci... OMIM:611302
Spinocerebellar Ataxia 29
Broad-based gait, Truncal titubation, Dysmetria, Limb ataxia, Intention tremor, Dysdiadochokinesi... OMIM:117360
Sporadic Infantile Bilateral Striatal Necrosis
Hemiplegia, Progressive extrapyramidal muscular rigidity, Bradykinesia, Resting tremor, Babinski ... ORPHA:225147
Mohr-Tranebjaerg Syndrome
Tremor, Spasticity, Abnormal posturing OMIM:304700
Classic Pantothenate Kinase-Associated Neurodegeneration
Inability to walk, Opisthotonus, Tip-toe gait, Gait disturbance, Frequent falls, Spasticity, Abno... ORPHA:216866
Autosomal Spastic Paraplegia Type 58
Torticollis, Erratic myoclonus, Dysmetria, Tip-toe gait, Intention tremor, Babinski sign, Abnorma... ORPHA:397946
Dystonia 1, Torsion, Autosomal Dominant
Torticollis, Hypertonia, Inability to walk, Blepharospasm, Babinski sign, Tremor, Abnormal posturing OMIM:128100
Spinocerebellar Ataxia, Autosomal Recessive 30
Ataxia, Dysmetria, Tremor, Titubation, Unsteady gait OMIM:619405
Autosomal Recessive Spastic Paraplegia Type 75
Dysmetria, Impaired vibratory sensation, Babinski sign, Abnormal pyramidal sign, Spastic parapleg... ORPHA:459056
Pelizaeus-Merzbacher Disease, Classic Form
Ataxia, Abnormality of extrapyramidal motor function, Abnormal pyramidal sign, Head tremor, Athet... ORPHA:280219
Spinocerebellar Ataxia Type 18
Dysmetria, Head tremor, Titubation, Somatic sensory dysfunction, Gait ataxia ORPHA:98771
Sandifer Syndrome
Torticollis, Abnormal posturing ORPHA:71272
Methylmalonic Aciduria And Homocystinuria, Cblj Type
Abnormal posturing OMIM:614857
Unilateral Polymicrogyria
Pseudobulbar paralysis, Poor fine motor coordination, Myoclonus, Hemiparesis, Involuntary movemen... ORPHA:268943
Vici Syndrome
Abnormal posturing OMIM:242840
Non-Progressive Cerebellar Ataxia With Intellectual Disability
Ataxia, Dysmetria, Intention tremor, Abnormal pyramidal sign, Nonprogressive cerebellar ataxia, U... ORPHA:314647
Cerebellar Dysfunction With Variable Cognitive And Behavioral Abnormalities
Broad-based gait, Motor stereotypy, Ataxia, Poor gross motor coordination, Dysmetria, Hand tremor... OMIM:614756

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Camta1

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Camta1.

No publications found that use IMPC mice or data for Camta1.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

This service may be affected by the Covid-19 pandemic. See how

MGI Allele Allele Type Produced
Camta1tm455363(L1L2_GT2_LF2A_LacZ_BetactP_neo) KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors
Camta1tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, ES Cells

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter