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Gene: H4c14 MGI:2140113

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Gene Summary

Name:
H4 clustered histone 14
Synonyms:
H4,  X04652,  Hist2h4

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IMPC Data Collections

IMPC Phenotype Summary

Significant
Not Significant
Not tested

View all our phenotype data below

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

Phenotype System Allele Zyg Sex Life Stage P Value
preweaning lethality, incomplete penetrance H4c14em1(IMPC)Bay HOM Early adult 0.00

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Eye Morphology

VIP of right fundus

15 Images

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Eye Morphology

VIP of right eye

15 Images

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Eye Morphology

VIP of left eye

15 Images

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Eye Morphology

VIP of left fundus

15 Images

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Electrocardiogram (ECG)

Waveform Image

1 Images

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Human diseases caused by H4c14 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

The table below shows human diseases associated to H4c14 by orthology or direct annotation.

Disease Similarity of
phenotypes		 Matching phenotypes Source
Tessadori-Bicknell-Van Haaften Neurodevelopmental Syndrome 1
OMIM:619758
Tessadori-Bicknell-Van Haaften Neurodevelopmental Syndrome 3
OMIM:619950

The table below shows human diseases predicted to be associated to H4c14 by phenotypic similarity.

Disease Similarity of
phenotypes		 Matching phenotypes Source
Tessadori-Bicknell-Van Haaften Neurodevelopmental Syndrome 1
OMIM:619758
Tessadori-Bicknell-Van Haaften Neurodevelopmental Syndrome 3
OMIM:619950

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for H4c14

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to H4c14.

No publications found that use IMPC mice or data for H4c14.

Order Mouse and ES Cells

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MGI Allele Allele Type Produced
H4c14em1(IMPC)Bay Whole-gene deletion Mice

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