Gene: Fastkd5

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Phenotype System Allele Zyg Sex Life Stage P Value
embryonic lethality prior to organogenesis Fastkd5tm1.1(KOMP)Vlcg HOM   E9.5 0.00
preweaning lethality, complete penetrance Fastkd5tm1.1(KOMP)Vlcg HOM   Early adult 0.00
decreased circulating glucose level Fastkd5em1(IMPC)J HOM Early adult 1.59×10-05
abnormal sleep behavior Fastkd5em1(IMPC)J HOM Early adult 4.01×10-06
increased circulating potassium level Fastkd5em1(IMPC)J HOM Early adult 2.26×10-05
abnormal craniofacial morphology Fastkd5tm1.1(KOMP)Vlcg HET E12.5 0.00
shortened QRS complex duration Fastkd5em1(IMPC)J HOM Early adult 3.63×10-06
embryonic lethality prior to tooth bud stage Fastkd5tm1.1(KOMP)Vlcg HOM   E12.5 0.00
abnormal forebrain morphology Fastkd5tm1.1(KOMP)Vlcg HET E12.5 0.00
abnormal embryo size Fastkd5tm1.1(KOMP)Vlcg HET E12.5 0.00
increased prepulse inhibition Fastkd5em1(IMPC)J HOM   Early adult 3.64×10-05
impaired righting response Fastkd5em1(IMPC)J HOM Early adult 3.15×10-05

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Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (3/590)  (2/2)  Section images
Aorta 2 No  (1/590)  (2/2)  Section images
Brain 2 No  (3/590)  (2/2)  Section images
Brainstem 2 No  (2/590)  (2/2)  Section images
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (2/2)  Section images
Cerebellum 2 No  (3/590)  (2/2)  Section images
Cerebral cortex 2 No  (2/590)  (2/2)  Section images
Epididymis 2 No  (18/134)  (1/2)  Section images
Esophagus 2 No  (7/415)  (2/2)  Section images
Eye 2 No  (2/2)  Section images
Heart 2 No  (1/590)  (2/2)  Section images
Hippocampus 2 No  (3/590)  (2/2)  Section images
Hypothalamus 2 No  (2/590)  (2/2)  Section images
Kidney 2 No  (20/590)  (2/2)  Section images
Large intestine 2 No  (10/590)  (2/2)  Section images
Liver 2 No N/A
Lower urinary tract 2 No  (1/590) N/A
Lung 2 No  (1/590)  (2/2)  Section images
Lymph node 2 No  (2/2)  Section images
Mammary gland 2 No  (1/2)  Section images
Midbrain 2 No  (2/2)  Section images
Olfactory lobe 2 No  (2/590)  (2/2)  Section images
Ovary 2 No  (1/590)  (1/2)  Section images
Oviduct 2 No  (1/2)  Section images
Pancreas 2 No  (5/590)  (2/2)  Section images
Peripheral nervous system 2 No  (1/590)  (2/2)  Section images
Peyer's patch 2 No  (2/2)  Section images
Pituitary gland 2 No  (1/590)  (2/2)  Section images
Prostate gland 2 No  (12/590) N/A
Skeletal muscle 2 No  (2/2)  Section images
Skin 2 No  (2/2)  Section images
Small intestine 2 No  (9/590)  (2/2)  Section images
Spinal cord 2 No  (2/590)  (2/2)  Section images
Spleen 2 No  (2/590)  (2/2)  Section images
Stomach 2 No  (13/590)  (2/2)  Section images
Striatum 2 No  (3/590)  (2/2)  Section images
Submandibular gland 2 No  (2/132)  Section images
Testis 2 No  (5/590)  (1/2)  Section images
Thalamus 2 No  (2/2)  Section images
Thymus 2 No  (2/2)  Section images
Thyroid gland 2 No  (16/590) N/A
Trachea 2 No  (2/590)  (2/2)  Section images
Urinary bladder 2 No  (2/2)  Section images
Uterus 2 No  (1/2)  Section images
Vascular system 2 No  (2/2)  Section images
Vesicular gland 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/506)  (2/2) N/A
Dorsal root ganglion 2  (1/61)  (2/2) N/A
Ear 2  (1/506)  (2/2) N/A
Embryo 2  (1/507)  (2/2)  Wholemount images
Eye 2  (1/506)  (2/2) N/A
Foot 2  (1/506)  (2/2) N/A
Forebrain 2  (1/506)  (2/2) N/A
Forelimb 2  (1/506)  (2/2) N/A
Fronto-nasal process 2  (1/62) Image Only N/A
Hand 2  (1/506)  (2/2) N/A
Head 2  (5/506)  (2/2) N/A
Heart 2  (1/506)  (2/2) N/A
Hindbrain 2  (6/506)  (2/2) N/A
Hindlimb 2  (1/506)  (2/2) N/A
Liver 2  (1/504)  (2/2) N/A
Lung 2  (1/504) Image Only N/A
Mandibular process 2  (1/506)  (2/2) N/A
Maxillary process 2  (1/506)  (2/2) N/A
Midbrain 2  (1/506)  (2/2) N/A
Nose 2  (1/76)  (2/2) N/A
Oral cavity 2  (1/504) Image Only N/A
Skin 2  (1/506)  (2/2) N/A
Spinal cord 2  (1/73)  (2/2) N/A
Tail 2  (1/506)  (2/2) N/A
Tail somite 2  (1/506) N/A

 Associated Images

X-ray: XRay Images Forepaw
18 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
18 Images
Sleep Wake: Wake state (bmp file)
14 Images
X-ray: XRay Images Skull Lateral Orientation
18 Images
X-ray: XRay Images Whole Body Dorso Ventral
18 Images
Original Image
Adult LacZ: LacZ Images Section
41 Images
X-ray: XRay Images Whole Body Lateral Orientation
18 Images
Embryo LacZ: LacZ images wholemount
8 Images
Eye Morphology: Images Slit Lamp
2 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
3 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Fastkd5tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice
Fastkd5em1(IMPC)J Indel causing a Frameshift Mutation Mice
Fastkd5tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells

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