Dlgap4 | DLG associated protein 4

GeneMGI:2138865Synonyms: WBP16, PSD-95/SAP90 binding protein 4, +3 more

Physiological systems

15 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Adipose tissue Growth/size/body region Hematopoietic system

11 No significant impact

9 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased circulating creatinine level1 supporting datasetDlgap4tm1b(KOMP)WtsiheterozygoteEarly adult9.94x10-8 
decreased total body fat amount1 supporting datasetDlgap4tm1b(KOMP)WtsiheterozygoteEarly adult1.92x10-5 
decreased fasting circulating glucose level1 supporting datasetDlgap4tm1b(KOMP)WtsiheterozygoteEarly adult2.85x10-6 
decreased erythrocyte cell number1 supporting datasetDlgap4tm1b(KOMP)WtsiheterozygoteEarly adult3.21x10-5 
increased lean body mass1 supporting datasetDlgap4tm1b(KOMP)WtsiheterozygoteEarly adult7.71x10-6 
increased blood urea nitrogen level1 supporting datasetDlgap4tm1b(KOMP)WtsiheterozygoteEarly adult7.34x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Dlgap4tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Dlgap4tm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Dlgap4tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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