Gene: Dtnbp1

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Name
dystrobrevin binding protein 1
MGI ID
MGI:2137586
Synonyms
dysbindin 5430437B18Rik sdy Bloc1s8
Viability
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal iris pigmentation Dtnbp1tm1b(EUCOMM)Hmgu HOM Early adult 3.04×10-18
decreased grip strength Dtnbp1tm1b(EUCOMM)Hmgu HOM   Early adult 2.20×10-06
abnormal uterus morphology Dtnbp1tm1b(EUCOMM)Hmgu HOM Early adult 0.00
abnormal coat/hair pigmentation Dtnbp1tm1b(EUCOMM)Hmgu HOM Early adult 4.28×10-14
increased leukocyte cell number Dtnbp1tm1b(EUCOMM)Hmgu HOM Early adult 5.39×10-06

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 Expression

Expression data not available

 Associated Images

Gross Pathology and Tissue Collection
8 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
15 Images
Eye Morphology: Images Slit Lamp
4 Images
X-ray: XRay Images Whole Body Lateral Orientation
15 Images
X-ray: XRay Images Whole Body Dorso Ventral
15 Images
X-ray: XRay Images Skull Lateral Orientation
15 Images
X-ray: XRay Images Hind Leg and Hip
15 Images
Combined SHIRPA and Dysmorphology
15 Images
Eye Morphology: Images Ophthalmoscopy
10 Images
Histopathology
2 Images

 Disease Models

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 Histopathology

Phenotype Allele Zygosity Sex Life Stage
Eye - MPATH pathological process term developmental dysplasia Dtnbp1tm1b(EUCOMM)Hmgu HOM Early adult

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MGI Allele Allele Type Produced
Dtnbp1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Dtnbp1tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice, Tissue

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