Gene: Dtnbp1

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Name
dystrobrevin binding protein 1
MGI ID
MGI:2137586
Synonyms
dysbindin 5430437B18Rik sdy Bloc1s8
Viability
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal iris pigmentation Dtnbp1tm1b(EUCOMM)Hmgu HOM Early adult 5.07×10-26
abnormal leukocyte cell number Dtnbp1tm1b(EUCOMM)Hmgu HOM Early adult 1.04×10-05
abnormal uterus morphology Dtnbp1tm1b(EUCOMM)Hmgu HOM Early adult 0.00
abnormal coat/hair pigmentation Dtnbp1tm1b(EUCOMM)Hmgu HOM Early adult 4.23×10-28
abnormal grip strength Dtnbp1tm1b(EUCOMM)Hmgu HOM Early adult 7.43×10-06
abnormal retina morphology Dtnbp1tm1b(EUCOMM)Hmgu HOM Early adult 5.93×10-16

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Viewing: all phenotypes

 Expression

Expression data not available

 Associated Images

Combined SHIRPA and Dysmorphology
15 Images
X-ray: XRay Images Whole Body Dorso Ventral
15 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
15 Images
X-ray: XRay Images Hind Leg and Hip
15 Images
X-ray: XRay Images Whole Body Lateral Orientation
30 Images
Eye Morphology: Images Ophthalmoscopy
16 Images
Gross Pathology and Tissue Collection
8 Images
Eye Morphology: Images Slit Lamp
4 Images
Histopathology
4 Images

 Disease Models

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 Histopathology

Phenotype Allele Zygosity Sex Life Stage
Eye with optic nerve - pigmentation Dtnbp1tm1b(EUCOMM)Hmgu HOM Early adult

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MGI Allele Allele Type Produced
Dtnbp1tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Dtnbp1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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