Genes Phenotypes

Gene: Dtnbp1

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Name
dystrobrevin binding protein 1
MGI ID
MGI:2137586
Synonyms
sdy dysbindin 5430437B18Rik Bloc1s8
Viability
Homozygous - Viable
View
N/A
Other links
MGI   Ensembl  
Significant phenotypes (7) Measurements chart (229) All data table (386)
Expression & images (0) Disease models (0) Histopathology (1) Order (2)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal coat/hair pigmentation Dtnbp1tm1b(EUCOMM)Hmgu HOM postnatal 6.22×10-17
abnormal retina morphology Dtnbp1tm1b(EUCOMM)Hmgu HOM postnatal 3.37×10-09
small superior vagus ganglion Dtnbp1tm1b(EUCOMM)Hmgu HOM postnatal 0.00
abnormal uterus morphology Dtnbp1tm1b(EUCOMM)Hmgu HOM postnatal 0.00
decreased grip strength Dtnbp1tm1b(EUCOMM)Hmgu HOM postnatal 9.73×10-06
abnormal iris pigmentation Dtnbp1tm1b(EUCOMM)Hmgu HOM postnatal 7.95×10-16
increased circulating phosphate level Dtnbp1tm1b(EUCOMM)Hmgu HOM postnatal 4.61×10-05

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Select physiological systems to view:
Viewing: all phenotypes

 Expression

Expression data not available

 Associated Images

X-ray: XRay Images Dorso Ventral
15 Images
X-ray: XRay Images Hind Leg and Hip
15 Images
X-ray: XRay Images Lateral Orientation
30 Images
Gross Pathology and Tissue Collection
8 Images
Eye Morphology: Images Slit Lamp
4 Images
Eye Morphology: Images Ophthalmoscopy
16 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
15 Images
Combined SHIRPA and Dysmorphology
15 Images
Histopathology
4 Images

 Disease Models

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 Histopathology

Phenotype Allele Zygosity Sex Life Stage
Eye with optic nerve - pigmentation Dtnbp1tm1b(EUCOMM)Hmgu HOM postnatal

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Dtnbp1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Dtnbp1tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice, Tissue

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