Gene: Lce3c

Name
late cornified envelope 3C
MGI ID
MGI:2135932
Synonyms
2300007B01Rik Sprrl1 Eig3
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N/A
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Significant phenotypes (0) All measurements (503) Expression & images (0) Disease models (0) Order (2)
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Significant
Not Significant
Not tested

Filtered by: all phenotypes

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Allele Center Procedure / Parameter Zygosity Mutants Statistical
Method
P Value Status
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Total T cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw footpad size HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Effector gd cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Eye Morphology / Bulging eye HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / External genitalia morphology HOM 7f:8m Fisher Exact Test framework 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Total CD4+ NKT cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / B cell number HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_034_001' control subset (Female - 48, Male - 34) to allow the application of RR plus framework.
Lce3ctm2a(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / NKT cell number HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_026_001' control subset (Female - 48, Male - 34) to allow the application of RR plus framework.
Lce3ctm2a(EUCOMM)Wtsi WTSI Bone marrow immunophenotyping / Pre-pro B cells (Hardy fraction A) - % of B220+ HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ Treg cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Eye Morphology / Iris/Pupil HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Snout morphology HOM 7f:8m Fisher Exact Test framework 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Hematology / Mean cell hemoglobin concentration HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.968 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI X-ray / Kyphosis HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI X-ray / Lumbar processes HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Incisors morphology HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total B cells - % of CD45+ HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI X-ray / Fibula HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI X-ray / Shape of vertebrae HOM 7f:7m Fisher Exact Test framework 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Trunk curl HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Naive CD8+ T cells - % of CD8+ HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector gd T cells - % of gd T cells HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Body Composition (DEXA lean/fat) / Body length HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0992 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ gd T cells - % of CD45+ HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Plasmacytoid DC - % of DC HOM 3f:3m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Eye Morphology / Lens Opacity HOM 7f:7m Fisher Exact Test framework 0.196 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Limb skin appearance HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Ly6C+ mature NK cells - % of mature NK cells HOM 3f:3m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Conventional DC (cDC) - % of CD45+ HOM 3f:3m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Ly6Clow monocyte percentage HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_018_001' control subset (Female - 48, Male - 34) to allow the application of RR plus framework.
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Follicular B cells - % of B2 cells HOM 3f:3m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindlimb size HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw morphology HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector CD4+ T helper cells - % of CD45+ HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Follicular B cells - % of CD45+ HOM 0f:0m Manual Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ Treg cells - % of Treg HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI X-ray / Zygomatic bone HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head skin colour HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head coat/hair length HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Ventral coat/hair colour pattern HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Limb coat/hair length HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI X-ray / Shape of ribs HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / CD4+ T helper cells - % of CD4+ HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Grip Strength / Forelimb and hindlimb grip strength normalised against body weight HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.406 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Macrophages - % of CD45+ HOM 3f:3m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Intraperitoneal glucose tolerance test (IPGTT) / Area under glucose response curve HOM 7f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.0557 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / CD4+ T helper cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD4+ alpha beta T cell percentage HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_003_001' control subset (Female - 48, Male - 34) to allow the application of RR plus framework.
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail length HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ CD4+ NKT cells - % of CD45+ HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Total CD4- NKT cells - % of NKT cells HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Bone marrow immunophenotyping / Myeloid cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ CD4+ T helper cells - % of CD4+ T helper cells HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Total CD8+ T cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Germinal centre B cells - % of B2 cells HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Viability Primary Screen / Outcome HOM 32f:32m Supplied as data Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ CD4- NKT cells - % of CD4- NKT cells HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Plasmacytoid DC - % of DC HOM 3f:3m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head bobbing/circling HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw nail colour HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Digit coat/hair colour pattern HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / B1a cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting CD8+ T cells - % of CD45+ HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Eye Morphology / Corneal vascularization HOM 7f:7m Fisher Exact Test framework 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Eye Morphology / Retinal Blood Vessels Pattern HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head size HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Hematology / Platelet count HOM 7f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.149 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD4+ CD44+ CD62L- alpha beta effector T cell percentage HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_009_001' control subset (Female - 48, Male - 34) to allow the application of RR plus framework.
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / External genitalia HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Resting gd T cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting CD4+ T helper cells - % of CD45+ HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindlimb morphology HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Follicular B cells - % of B2 cells HOM 0f:0m Manual Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ CD4- NKT cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Transfer arousal HOM 7f:8m Fisher Exact Test framework 0.284 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD8+ KLRG1+ alpha beta T cell number HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_033_001' control subset (Female - 48, Male - 34) to allow the application of RR plus framework.
Lce3ctm2a(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Gamma delta T cell number HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_025_001' control subset (Female - 48, Male - 34) to allow the application of RR plus framework.
Lce3ctm2a(EUCOMM)Wtsi WTSI Eye Morphology / Pupil Position HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Limb skin colour HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD8+ CD44+ CD62L- alpha beta effector T cell percentage HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_010_001' control subset (Female - 48, Male - 34) to allow the application of RR plus framework.
Lce3ctm2a(EUCOMM)Wtsi WTSI Ear epidermis immunophenotyping / Average volume of LC HOM 1f:1m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Ear epidermis immunophenotyping / Average volume of LC HOM 2f:2m Manual 1.00 Not processed - Data analysis not performed or not applicable
Lce3ctm2a(EUCOMM)Wtsi WTSI Ear epidermis immunophenotyping / Average volume of LC HOM 2f:2m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Ear epidermis immunophenotyping / Average volume of LC HOM 1f:1m Manual 1.00 Not processed - Data analysis not performed or not applicable
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ CD8+ T cells - % of CD8+ HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI X-ray / Scoliosis HOM 7f:7m Fisher Exact Test framework 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Plasmacytoid DC - % of CD45+ HOM 3f:3m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Incisor colour HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Neutrophil percentage HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_019_001' control subset (Female - 48, Male - 34) to allow the application of RR plus framework.
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Early germinal centre B cells - % of CD45+ HOM 0f:0m Manual Success
Lce3ctm2a(EUCOMM)Wtsi WTSI X-ray / Fusion of vertebrae HOM 7f:7m Fisher Exact Test framework 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Conventional DC (cDC) - % of CD45+ HOM 3f:3m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI X-ray / Tibia HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / CD5+ gd T cells - % of gd T cells HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head skin appearance HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Resting Treg cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Grip Strength / Forelimb and hindlimb grip strength measurement mean HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.581 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Paw footpad skin appearance HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting CD4+ NKT cells - % of CD45+ HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD8+ alpha beta T cell percentage HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_004_001' control subset (Female - 48, Male - 34) to allow the application of RR plus framework.
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total CD4+ T cells - % of ab T cells HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Digit coat/hair appearance HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Eye Morphology / Lens HOM 7f:7m Fisher Exact Test framework 0.196 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting gd T cells - % of gd T cells HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Grip Strength / Forelimb grip strength normalised against body weight HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.737 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Effector CD4+ T helper cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / CD11b-high cDC - % of CD45+ HOM 3f:3m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail morphology HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / KLRG1+ mature NK cell percentage HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_011_001' control subset (Female - 48, Male - 34) to allow the application of RR plus framework.
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Resting CD4+ T helper cells - % of CD4+ T helper cells HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Ventral coat/hair colour HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Total B cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Germinal centre B cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Body Composition (DEXA lean/fat) / Bone Mineral Content (excluding skull) HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.825 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Ly6C+ NKT cells - % of NKT cells HOM 3f:3m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / CD11b-low cDC - % of CD45+ HOM 3f:3m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Corneal touch reflex HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Contact righting reflex HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw nail morphology HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector CD8+ T cells - % of CD45+ HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Eye Morphology / Persistence of hyaloid vascular system HOM 7f:7m Fisher Exact Test framework 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector NK cells - % of CD45+ HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Bone marrow immunophenotyping / Granulocytes - % of CD45+ HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI X-ray / Maxilla/Pre-maxilla HOM 7f:7m Fisher Exact Test framework 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Mature NK cells - % of NK cellls HOM 3f:3m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Gait (inc. ataxia) HOM 7f:8m Fisher Exact Test framework 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector CD4- NKT cells - % of CD45+ HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail coat/hair appearance HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Naive CD8+ T cells - % of CD45+ HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting NK cells - % of NK cells HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI X-ray / Caudal processes HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Ventral skin appearance HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindlimb HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Total B2 cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head morphology HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Dorsal coat/hair colour HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI X-ray / Number of ribs right HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'IMPC_XRY_008_001' control subset (Female - 36, Male - 34) to allow the application of RR plus framework.
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Resting CD4+ NKT cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total DC - % of CD45+ HOM 3f:3m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD4+ CD25+ alpha beta regulatory T cell percentage HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_008_001' control subset (Female - 48, Male - 34) to allow the application of RR plus framework.
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ gd T cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Resting Treg cells - % of Treg HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting CD4- NKT cells - % of CD4- NKT cells HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ CD4+ T helper cells - % of CD45+ HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Transitional 1 B cells - % of B2 cells HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Convulsions HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Plasmacytoid DC - % of CD45+ HOM 3f:3m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw digit size HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Monocyte number HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_036_001' control subset (Female - 48, Male - 34) to allow the application of RR plus framework.
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector CD4+ T helper cells - % of CD4+ T helper cells HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw digit fusion HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / CD103+ CD11b-low cDC - % of CD45+ HOM 3f:3m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Ear epidermis immunophenotyping / Average branch length of LC HOM 1f:1m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Ear epidermis immunophenotyping / Average branch length of LC HOM 2f:2m Manual 1.00 Not processed - Data analysis not performed or not applicable
Lce3ctm2a(EUCOMM)Wtsi WTSI Ear epidermis immunophenotyping / Average branch length of LC HOM 1f:1m Manual 1.00 Not processed - Data analysis not performed or not applicable
Lce3ctm2a(EUCOMM)Wtsi WTSI Ear epidermis immunophenotyping / Average branch length of LC HOM 2f:2m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Effector Treg cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Effector NK cells - % of NK cells HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Grip Strength / Forelimb grip strength measurement mean HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.416 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting Treg cells - % of Treg HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Ventral coat/hair appearance HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI DSS Histology / Pre-Day 10 Death HOM 2f:2m - 1.00 FAILED - Not enough mutant or control data
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Limb coat/hair appearance HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI X-ray / Femur HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Eosinophil number HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_040_001' control subset (Female - 48, Male - 34) to allow the application of RR plus framework.
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Pinna HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Eye Morphology / Cornea HOM 7f:7m Fisher Exact Test framework 0.624 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Resting CD4+ T helper cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Germinal centre B cells - % of B2 cells HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Effector CD4+ T helper cells - % of CD4+ T helper cells HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Resting CD4+ NKT cells - % of CD4+ NKT cells HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Eosinophil percentage HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_020_001' control subset (Female - 48, Male - 34) to allow the application of RR plus framework.
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Resting CD8+ T cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Bone marrow immunophenotyping / Immature B cells (Hardy fraction E) - % of B220+ HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Body Composition (DEXA lean/fat) / Bone Mineral Density (excluding skull) HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0207 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Follicular B cells - % of CD45+ HOM 3f:3m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Pinna position HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Hematology / Red blood cell count HOM 7f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.0196 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Paw coat/hair colour HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw digit count HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting gd T cells - % of CD45+ HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Eye Morphology / Iris Pigmentation HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD4+ KLRG1+ alpha beta T cell percentage HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_012_001' control subset (Female - 48, Male - 34) to allow the application of RR plus framework.
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Mature NK cells - % of lymphocytes HOM 3f:3m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Paw footpad skin colour HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / CD11b-high cDC - % of cDC HOM 3f:3m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Granulocytes - % of CD45+ HOM 3f:3m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Startle response HOM 7f:8m Fisher Exact Test framework 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI X-ray / Thoracic processes HOM 7f:7m Fisher Exact Test framework 0.0400 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI X-ray / Humerus HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector CD8+ T cells - % of CD8+ HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector CD4+ NKT cells - % of CD4+ NKT cells HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / NK cell number HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_027_001' control subset (Female - 48, Male - 34) to allow the application of RR plus framework.
Lce3ctm2a(EUCOMM)Wtsi WTSI Bone marrow immunophenotyping / Total B cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / CD5+ gd T cells - % of gd T cells HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI X-ray / Number of lumbar vertebrae HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'IMPC_XRY_015_001' control subset (Female - 36, Male - 34) to allow the application of RR plus framework.
Lce3ctm2a(EUCOMM)Wtsi WTSI X-ray / Lordosis HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Ventral skin colour HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Eosinophils - % of CD45+ HOM 3f:3m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Effector CD4+ NKT cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Memory B cells - % of B2 cells HOM 0f:0m Manual Success
Lce3ctm2a(EUCOMM)Wtsi WTSI X-ray / Ulna HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI X-ray / Sacral processes HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Resting CD4- NKT cells - % of CD4- NKT cells HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail coat/hair length HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Effector Treg cells - % of Treg HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ CD8+ T cells - % of CD45+ HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Total DC - % of CD45+ HOM 3f:3m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw digit count HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / External genitalia size HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Digit coat/hair presence HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI X-ray / Number of caudal vertebrae HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'IMPC_XRY_017_001' control subset (Female - 36, Male - 34) to allow the application of RR plus framework.
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ NK cells - % of NK cells HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / NK cell percentage HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_007_001' control subset (Female - 48, Male - 34) to allow the application of RR plus framework.
Lce3ctm2a(EUCOMM)Wtsi WTSI X-ray / Number of ribs left HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'IMPC_XRY_009_001' control subset (Female - 36, Male - 34) to allow the application of RR plus framework.
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Memory B cells - % of CD45+ HOM 0f:0m Manual Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw nail colour HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Ventral coat/hair length HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Body Composition (DEXA lean/fat) / Bone Area HOM 7f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.117 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Total NK cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Total CD4+ T cells - % of ab T cells HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Transitional 2 B cells - % of B2 cells HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / IgD+ mature B cell number HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_035_001' control subset (Female - 48, Male - 34) to allow the application of RR plus framework.
Lce3ctm2a(EUCOMM)Wtsi WTSI Ear epidermis immunophenotyping / Average roundness of LC HOM 1f:1m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Ear epidermis immunophenotyping / Average roundness of LC HOM 2f:2m Manual 1.00 Not processed - Data analysis not performed or not applicable
Lce3ctm2a(EUCOMM)Wtsi WTSI Ear epidermis immunophenotyping / Average roundness of LC HOM 2f:2m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Ear epidermis immunophenotyping / Average roundness of LC HOM 1f:1m Manual 1.00 Not processed - Data analysis not performed or not applicable
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total CD4- NKT cells - % of CD45+ HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw digit morphology HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting CD4+ T helper cells - % of CD4+ T helper cells HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail skin colour HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Bone marrow immunophenotyping / Mature B cells (Hardy fraction F) - % of B220+ HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Dorsal coat/hair presence HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Paw coat/hair presence HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Pinna morphology HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw digit size HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Transitional 2 B cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Bone marrow immunophenotyping / Mature B cells (Hardy fraction F) - % of CD45+ HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD8+ KLRG1+ alpha beta T cell percentage HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_013_001' control subset (Female - 48, Male - 34) to allow the application of RR plus framework.
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ CD4+ T helper cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Effector CD8+ T cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ CD4+ NKT cells - % of CD4+ NKT cells HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Fertility of Homozygous Knock-out Mice / Gross Findings Female HOM f:m Supplied as data Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Bone marrow immunophenotyping / Pre-pro B cells (Hardy fraction A) - % of CD45+ HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI X-ray / Skull shape HOM 7f:7m Fisher Exact Test framework 0.0267 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total CD8+ T cells - % of ab T cells HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forelimb HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Ear epidermis immunophenotyping / Langerhans cell (LC) count HOM 1f:1m Manual 1.00 Not processed - Data analysis not performed or not applicable
Lce3ctm2a(EUCOMM)Wtsi WTSI Ear epidermis immunophenotyping / Langerhans cell (LC) count HOM 1f:1m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Ear epidermis immunophenotyping / Langerhans cell (LC) count HOM 2f:2m Manual 1.00 Not processed - Data analysis not performed or not applicable
Lce3ctm2a(EUCOMM)Wtsi WTSI Ear epidermis immunophenotyping / Langerhans cell (LC) count HOM 2f:2m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Digit coat/hair colour HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Insulin Blood Level / Insulin HOM 7f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.0540 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Ly6C+ mature NK cells - % of lymphocytes HOM 3f:3m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD4+ CD25+ alpha beta regulatory T cell number HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_028_001' control subset (Female - 48, Male - 34) to allow the application of RR plus framework.
Lce3ctm2a(EUCOMM)Wtsi WTSI Body Composition (DEXA lean/fat) / Lean mass HOM 7f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.0701 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Effector CD4- NKT cells - % of CD4- NKT cells HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Eye Morphology / Pupil Light Response HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Eye Morphology / Corneal opacity HOM 7f:7m Fisher Exact Test framework 0.608 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / CD11b-low cDC - % of cDC HOM 3f:3m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Monocytes - % of CD45+ HOM 3f:3m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI X-ray / Number of pelvic vertebrae HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'IMPC_XRY_016_001' control subset (Female - 36, Male - 34) to allow the application of RR plus framework.
Lce3ctm2a(EUCOMM)Wtsi WTSI X-ray / Shape of ribcage HOM 7f:7m Fisher Exact Test framework 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tremor HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Hematology / White blood cell count HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.617 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total CD4+ NKT cells - % of NKT cells HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Marginal zone B cells - % of B2 cells HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Eosinophils - % of CD45+ HOM 3f:3m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ NK cells - % of NK cells HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Plasma cells - % of CD45+ HOM 0f:0m Manual Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Naive CD8+ T cells - % of CD8+ HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Dorsal coat/hair appearance HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI X-ray / Number of thoracic vertebrae HOM 7f:7m Not processed 1.00 FAILED - No variability in dependent variable 'IMPC_XRY_014_001'.
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Marginal zone precursor B cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Limb coat/hair colour HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ CD4+ T helper cells - % of CD4+ T helper cells HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ CD4- NKT cells - % of CD4- NKT cells HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / B1a cells - % of CD45+ HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Memory B cells - % of CD45+ HOM 0f:0m Manual Success
Lce3ctm2a(EUCOMM)Wtsi WTSI X-ray / Radius HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail coat/hair colour HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Hematology / Mean platelet volume HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.517 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / NKT cell percentage HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_006_001' control subset (Female - 48, Male - 34) to allow the application of RR plus framework.
Lce3ctm2a(EUCOMM)Wtsi WTSI X-ray / Brachydactyly HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Resting gd T cells - % of gd T cells HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total gd T cells - % of CD45+ HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail skin appearance HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw nail morphology HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total CD4- NKT cells - % of NKT cells HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI X-ray / Scapulae HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Alpha beta T cell number HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_022_001' control subset (Female - 48, Male - 34) to allow the application of RR plus framework.
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head coat/hair presence HOM 7f:8m Fisher Exact Test framework 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / CD4+ T helper cells - % of CD4+ HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Naive CD8+ T cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw digit fusion HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Plasma cells - % of B2 cells HOM 0f:0m Manual Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Immature NK cells - % of lymphocytes HOM 3f:3m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Eye Morphology / Retina (combined) HOM 7f:7m Not processed Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting Treg cells - % of CD45+ HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Pinna size HOM 7f:8m Fisher Exact Test framework 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI X-ray / Polysyndactylism HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Hematology / Hematocrit HOM 7f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.00862 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Memory B cells - % of B2 cells HOM 0f:0m Manual Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Bone marrow immunophenotyping / Immature B cells (Hardy fraction E) - % of CD45+ HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Vibrissae shape HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Ly6Clow monocyte number HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_038_001' control subset (Female - 48, Male - 34) to allow the application of RR plus framework.
Lce3ctm2a(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD4+ CD44+ CD62L- alpha beta effector T cell number HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_029_001' control subset (Female - 48, Male - 34) to allow the application of RR plus framework.
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Total Treg cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / CD103+ CD11b-low cDC - % of CD11b-low cDC HOM 3f:3m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Eye Morphology / Pupil Dilation HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Body Composition (DEXA lean/fat) / Fat mass HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0980 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ CD4+ NKT cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Bone marrow immunophenotyping / Pro-B cells (Hardy fraction C) - % of B220+ HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / KLRG1+ mature NK cell number HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_031_001' control subset (Female - 48, Male - 34) to allow the application of RR plus framework.
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ CD4- NKT cells - % of CD45+ HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Paw coat/hair appearance HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ Treg cells - % of Treg HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total Treg cells - % of CD45+ HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Transitional 1 B cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forelimb size HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Dorsal skin colour HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail elevation HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector NK cells - % of NK cells HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw morphology HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Total CD4- NKT cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / CD103+ CD11b-low cDC - % of CD11b-low cDC HOM 3f:3m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / B cell percentage HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_014_001' control subset (Female - 48, Male - 34) to allow the application of RR plus framework.
Lce3ctm2a(EUCOMM)Wtsi WTSI X-ray / Clavicle HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Marginal zone B cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total Treg cells - % of CD4+ HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector CD4- NKT cells - % of CD4- NKT cells HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail coat/hair colour pattern HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Late germinal centre B cells - % of GC cells HOM 0f:0m Manual Success
Lce3ctm2a(EUCOMM)Wtsi WTSI X-ray / Digit integrity HOM 7f:7m Fisher Exact Test framework 0.167 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting CD4- NKT cells - % of CD45+ HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Total CD4+ NKT cells - % of NKT cells HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Marginal zone precursor B cells - % of B2 cells HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw nail length HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Body Composition (DEXA lean/fat) / Fat/Body weight HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.105 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Dorsal coat/hair colour pattern HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Effector gd T cells - % of gd T cells HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI X-ray / Number of cervical vertebrae HOM 7f:7m Not processed 1.00 FAILED - No variability in dependent variable 'IMPC_XRY_013_001'.
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total B2 cells - % of CD45+ HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Eye Morphology / Eyelid closure HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head coat/hair colour HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ CD8+ T cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Ly6Chigh monocyte number HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_037_001' control subset (Female - 48, Male - 34) to allow the application of RR plus framework.
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Limb coat/hair colour pattern HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Bone marrow immunophenotyping / Pre-B cells (Hardy fraction D) - % of CD45+ HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Gamma delta T cell percentage HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_005_001' control subset (Female - 48, Male - 34) to allow the application of RR plus framework.
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector Treg cells - % of CD45+ HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Late germinal centre B cells - % of CD45+ HOM 0f:0m Manual Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Resting NK cells - % of NK cells HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw digit morphology HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / CD5+ gd T cells - % of CD45+ HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Hematology / Hemoglobin HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.121 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Ly6C+ immature NK cells - % of lymphocytes HOM 3f:3m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Plasma cells - % of B2 cells HOM 0f:0m Manual Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Total T cell number HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_021_001' control subset (Female - 48, Male - 34) to allow the application of RR plus framework.
Lce3ctm2a(EUCOMM)Wtsi WTSI X-ray / Syndactylism HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Ly6C+ NKT cells - % of lymphocytes HOM 3f:3m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector gd cells - % of CD45+ HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total ab T cells - % of CD45+ HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forelimb morphology HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / CD103+ CD11b-low cDC - % of CD45+ HOM 3f:3m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Eye Morphology / Optic Disc HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Eye Morphology / Narrow eye opening HOM 7f:7m Fisher Exact Test framework 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / CD11b-low cDC - % of cDC HOM 3f:3m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Heart Weight / Heart weight HOM 7f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.101 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Vibrissae size HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Bone marrow immunophenotyping / Pre-B cells (Hardy fraction D) - % of B220+ HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting CD4+ NKT cells - % of CD4+ NKT cells HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Dorsal skin appearance HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Vibrissae colour HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD4+ KLRG1+ alpha beta T cell number HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_032_001' control subset (Female - 48, Male - 34) to allow the application of RR plus framework.
Lce3ctm2a(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / IgD+ mature B cell percentage HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_015_001' control subset (Female - 48, Male - 34) to allow the application of RR plus framework.
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw footpad size HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Eye Morphology / Pupil Shape HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Fertility of Homozygous Knock-out Mice / Gross Findings Male HOM f:m Supplied as data Success
Lce3ctm2a(EUCOMM)Wtsi WTSI X-ray / Cervical processes HOM 7f:7m Fisher Exact Test framework 0.681 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Effector NK cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Total CD8+ T cells - % of ab T cells HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Effector CD4+ NKT cells - % of CD4+ NKT cells HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total NK cells - % of CD45+ HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Monocytes - % of CD45+ HOM 3f:3m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting CD8+ T cells - % of CD8+ HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Paw coat/hair colour pattern HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw nail count HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Body Composition (DEXA lean/fat) / Lean/Body weight HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0666 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD8+ alpha beta T cell number HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_024_001' control subset (Female - 48, Male - 34) to allow the application of RR plus framework.
Lce3ctm2a(EUCOMM)Wtsi WTSI Bone marrow immunophenotyping / Plasma cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Eye Morphology / Synechia HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Resting NK cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Monocyte percentage HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_016_001' control subset (Female - 48, Male - 34) to allow the application of RR plus framework.
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Intraperitoneal glucose tolerance test (IPGTT) / Initial response to glucose challenge HOM 7f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.0952 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Antigen Specific Immunoglobulin Assay / TetC specific IgG1 HOM 4f:0m Not processed 1.00 FAILED - No variability in dependent variable 'SLM_AGS_002_001'.
Lce3ctm2a(EUCOMM)Wtsi WTSI X-ray / Transitional vertebrae HOM 7f:7m Fisher Exact Test framework 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Early germinal centre B cells - % of CD45+ HOM 0f:0m Manual Success
Lce3ctm2a(EUCOMM)Wtsi WTSI X-ray / Pelvis HOM 7f:7m Fisher Exact Test framework 0.196 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Late germinal centre B cells - % of CD45+ HOM 0f:0m Manual Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Pinna rotation HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Total ab T cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Eye Morphology / Eyelid morphology HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI X-ray / Shape of spine HOM 7f:7m Fisher Exact Test framework 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Hematology / Mean cell volume HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.702 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Bone marrow immunophenotyping / Pro-B cells (Hardy fraction C) - % of CD45+ HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / CD11b-low cDC - % of CD45+ HOM 3f:3m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Effector CD8+ T cells - % of CD8+ HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / CD11b-high cDC - % of cDC HOM 3f:3m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Total NKT cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Pinna skin colour HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ gd T cells - % of gd T cells HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Positional passivity HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head coat/hair colour pattern HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw nail length HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Macrophages - % of CD45+ HOM 3f:3m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Digit coat/hair length HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total CD4+ T cells - % of CD45+ HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Eye Morphology / Retinal Blood Vessels HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Resting CD4- NKT cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Early germinal centre B cells - % of GC cells HOM 0f:0m Manual Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total CD8+ T cells - % of CD45+ HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Total gd T cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ CD4+ NKT cells - % of CD4+ NKT cells HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Vibrissae HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI X-ray / Mandibles HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Pinna touch reflex HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Ventral coat/hair presence HOM 7f:8m Fisher Exact Test framework 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Ly6C+ immature NK cells - % of immature NK cells HOM 3f:3m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector Treg cells - % of Treg HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Mouth morphology HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Granulocytes - % of CD45+ HOM 3f:3m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector CD4+ NKT cells - % of CD45+ HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI X-ray / Number of digits HOM 7f:7m Not processed 1.00 FAILED - No variability in dependent variable 'IMPC_XRY_028_001'.
Lce3ctm2a(EUCOMM)Wtsi WTSI Anti-nuclear antibody assay / ANA score HOM 3f:0m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Anti-nuclear antibody assay / ANA score HOM 0f:3m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Total T cell percentage HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_001_001' control subset (Female - 48, Male - 34) to allow the application of RR plus framework.
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting NK cells - % of CD45+ HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ CD8+ T cells - % of CD8+ HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Ly6Chigh monocyte percentage HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_017_001' control subset (Female - 48, Male - 34) to allow the application of RR plus framework.
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Limb coat/hair presence HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI DSS Histology / Average histology score HOM 2f:2m Not processed 1.00 FAILED - Not enough mutant or control data
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Incisors HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ NK cells - % of CD45+ HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw size HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Bone marrow immunophenotyping / Pro-B cells (Hardy fraction B) - % of CD45+ HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Plasma cells - % of CD45+ HOM 0f:0m Manual Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Anti-nuclear antibody assay / ANA classification HOM 0f:3m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Anti-nuclear antibody assay / ANA classification HOM 3f:0m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Eye Morphology / Eye Hemorrhage or Blood Presence HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI X-ray / Teeth HOM 7f:7m Fisher Exact Test framework 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Paw coat/hair length HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Immature NK cells - % of NK cells HOM 3f:3m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD4+ alpha beta T cell number HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_023_001' control subset (Female - 48, Male - 34) to allow the application of RR plus framework.
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / CD4+ T helper cells - % of CD45+ HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total NKT cells - % of CD45+ HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Eye Morphology / Fusion between cornea and lens HOM 7f:7m Fisher Exact Test framework 0.525 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Ear epidermis immunophenotyping / DETC coverage HOM 1f:1m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Ear epidermis immunophenotyping / DETC coverage HOM 1f:1m Manual 1.00 Not processed - Data analysis not performed or not applicable
Lce3ctm2a(EUCOMM)Wtsi WTSI Ear epidermis immunophenotyping / DETC coverage HOM 2f:2m Manual 1.00 Not processed - Data analysis not performed or not applicable
Lce3ctm2a(EUCOMM)Wtsi WTSI Ear epidermis immunophenotyping / DETC coverage HOM 2f:2m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Antigen Specific Immunoglobulin Assay / TetC specific IgG2 HOM 4f:0m Not processed 1.00 FAILED - Not enough data points in dependent variable 'SLM_AGS_003_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Lce3ctm2a(EUCOMM)Wtsi WTSI Hematology / Mean corpuscular hemoglobin HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.748 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Total CD4+ T cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail coat/hair presence HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw size HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ NK cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Intraperitoneal glucose tolerance test (IPGTT) / Fasted blood glucose concentration HOM 7f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.712 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Conventional DC (cDC) - % of DC HOM 3f:3m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Limb grasping HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Bone marrow immunophenotyping / T cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI X-ray / Fusion of ribs HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Body Composition (DEXA lean/fat) / BMC/Body weight HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.143 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ gd T cells - % of gd T cells HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head coat/hair appearance HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw nail count HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Neutrophil number HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_039_001' control subset (Female - 48, Male - 34) to allow the application of RR plus framework.
Lce3ctm2a(EUCOMM)Wtsi WTSI Eye Morphology / Retinal Blood Vessels Structure HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / CD11b-high cDC - % of CD45+ HOM 3f:3m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Germinal centre B cells - % of CD45+ HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD8+ CD44+ CD62L- alpha beta effector T cell number HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_030_001' control subset (Female - 48, Male - 34) to allow the application of RR plus framework.
Lce3ctm2a(EUCOMM)Wtsi WTSI X-ray / Joints HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Resting CD8+ T cells - % of CD8+ HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ Treg cells - % of CD45+ HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Pinna skin appearance HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI X-ray / Fusion of processes HOM 7f:7m Fisher Exact Test framework 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Hematology / Red blood cell distribution width HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.00792 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Snout size HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total CD4+ NKT cells - % of CD45+ HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Alpha beta T cell percentage HOM 7f:7m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'MGP_PBI_002_001' control subset (Female - 48, Male - 34) to allow the application of RR plus framework.
Lce3ctm2a(EUCOMM)Wtsi WTSI Ear epidermis immunophenotyping / Average no of branches on LC HOM 1f:1m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Ear epidermis immunophenotyping / Average no of branches on LC HOM 2f:2m Manual 1.00 Not processed - Data analysis not performed or not applicable
Lce3ctm2a(EUCOMM)Wtsi WTSI Ear epidermis immunophenotyping / Average no of branches on LC HOM 1f:1m Manual 1.00 Not processed - Data analysis not performed or not applicable
Lce3ctm2a(EUCOMM)Wtsi WTSI Ear epidermis immunophenotyping / Average no of branches on LC HOM 2f:2m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / CD5+ gd T cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Effector CD4- NKT cells - % of CD45+ HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Bone marrow immunophenotyping / Pro-B cells (Hardy fraction B) - % of B220+ HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total T cells - % of CD45+ HOM 5f:5m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Total Treg cells - % of CD4+ HOM 6f:6m Manual 1.00 Success
Lce3ctm2a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Dorsal coat/hair length HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK

 Expression

Expression data not available

 Associated Images

X-ray: XRay Images Dorso Ventral
44 Images
X-ray: XRay Images Forepaw
14 Images
X-ray: XRay Images Skull Lateral Orientation
14 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
16 Images
Eye Morphology: Images Slit Lamp
1 Images
X-ray: XRay Images Lateral Orientation
29 Images
Anti-nuclear antibody assay
6 Images
DSS Histology
8 Images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Lce3ctm2a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Lce3ctm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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