Gene: Sez6l

Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
decreased circulating serum albumin level Sez6ltm1b(EUCOMM)Hmgu HOM postnatal 5.86×10-06
abnormal gait Sez6ltm1b(EUCOMM)Hmgu HOM postnatal 1.31×10-05
hypoactivity Sez6ltm1b(EUCOMM)Hmgu HOM postnatal 7.32×10-19
decreased respiratory quotient Sez6ltm1b(EUCOMM)Hmgu HOM postnatal 1.12×10-06
abnormal behavior Sez6ltm1b(EUCOMM)Hmgu HOM postnatal 5.87×10-10
decreased eosinophil cell number Sez6ltm1b(EUCOMM)Hmgu HOM postnatal 1.03×10-06

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Bone 2 No N/A
Brain 2 No  (2/2) N/A
Brainstem 2 No N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Kidney 2 No  (18/584) N/A
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No N/A
Oral epithelium 2 No N/A
Ovary 2 No  (1/584) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/584) N/A
Parathyroid gland 2 No N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (1/2) N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584) N/A
Striatum 2 No N/A
Testis 2 No  (2/584)  (1/2) N/A
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No N/A
Uterus 2 No N/A
Vascular system 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 1  (6/485) N/A
Ear 1  (1/485) N/A
Embryo 1  (1/485) N/A
Eye 1  (1/485) N/A
Foot 1  (1/485) N/A
Forebrain 1  (1/485) N/A
Forelimb 1  (1/485) N/A
Hand 1  (1/485) N/A
Head 1  (5/485) N/A
Heart 1  (1/485) N/A
Hindbrain 1  (6/485) N/A
Hindlimb 1  (1/485) N/A
Liver 1  (1/485) N/A
Lung 1  (1/485) N/A
Mandibular process 1  (1/485) N/A
Maxillary process 1  (1/485) N/A
Midbrain 1  (1/485) N/A
Oral cavity 1  (1/485) N/A
Skin 1  (1/485) N/A
Tail 1  (1/485) N/A
Tail somite 1  (1/485) N/A

 Associated Images

X-ray: XRay Images Lateral Orientation
11 Images
Echo: M-Mode Images
32 Images
X-ray: XRay Images Dorso Ventral
11 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
11 Images
Embryo LacZ: LacZ images wholemount
8 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
5 Images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Sez6ltm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Sez6ltm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice
Sez6ltm1(NCOM)Mfgc Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells

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