Setdb1 | SET domain, bifurcated 1
Physiological systems
21 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Immune system Hematopoietic system Behavior/neurological Skeleton Mortality/aging
16 No significant impact
3 Not tested
Data collections
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:45Adult tissues
0Embryo tissues
preweaning lethality, complete penetrance | 2 supporting datasets | Setdb1tm1a(EUCOMM)Wtsi | homozygote | Early adult | N/A * | ||
increased startle reflex | 1 supporting dataset | Setdb1tm1a(EUCOMM)Wtsi | heterozygote | Early adult | 7.84x10-14 | ||
increased CD4-positive, alpha-beta T cell number | 1 supporting dataset | Setdb1tm1a(EUCOMM)Wtsi | heterozygote | Early adult | 6.09x10-7 | ||
increased bone mineral density | 1 supporting dataset | Setdb1tm1a(EUCOMM)Wtsi | heterozygote | Early adult | 1.38x10-5 |
| | | | | | | | | |
External links
No external links available for Setdb1.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
Setdb1tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |