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Gene: Setdb1

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Name
SET domain, bifurcated 1
MGI ID
MGI:1934229
Synonyms
ESET KMT1E
Viability
Data available
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (4) Measurements chart (275) All data table (800)
Expression & images (45) Disease models (0) Histopathology (2) Order (1)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
increased CD4-positive, alpha beta T cell number Setdb1tm1a(EUCOMM)Wtsi HET Early adult 1.57×10-05
preweaning lethality, complete penetrance Setdb1tm1a(EUCOMM)Wtsi HOM   Early adult 0.00
increased startle reflex Setdb1tm1a(EUCOMM)Wtsi HET Early adult 7.49×10-12
increased bone mineral density Setdb1tm1a(EUCOMM)Wtsi HET Early adult 9.48×10-08

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (4/583)  (2/2) N/A
Aorta 2 No  (1/583) N/A
Blood vessel 2 No N/A
Bone 2 No N/A
Brain 2 No  (4/583)  (2/2) N/A
Brainstem 2 No  (2/583) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (1/583)  (2/2) N/A
Cerebellum 2 No  (3/583) N/A
Cerebral cortex 2 No  (2/583) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No  (2/583)  (2/2) N/A
Hippocampus 2 No  (3/583) N/A
Hypothalamus 2 No  (2/583) N/A
Kidney 2 No  (21/583)  (2/2) N/A
Large intestine 2 No  (10/583) N/A
Liver 2 No  (2/2) N/A
Lower urinary tract 2 No  (1/583)  (2/2) N/A
Lung 2 No  (2/583)  (2/2) N/A
Lymph node 2 No  (1/583) N/A
Mammary gland 2 No N/A
Esophagus 2 No  (2/2) N/A
Olfactory lobe 2 No  (2/583) N/A
Ovary 2 No  (1/583)  (1/2) N/A
Oviduct 2 No  (1/2) N/A
Pancreas 2 No  (5/583) N/A
Parathyroid gland 2 No  (1/563)  (2/2) N/A
Peripheral nervous system 2 No  (2/583)  (2/2) N/A
Peyer's patch 2 No  (1/176) N/A
Pituitary gland 2 No  (1/583)  (1/2) N/A
Prostate gland 2 No  (12/583) N/A
Skeletal muscle tissue 2 No  (2/2) N/A
Skin 2 No  (1/583)  (2/2) N/A
Small intestine 2 No  (9/583)  (2/2) N/A
Spinal cord 2 No  (3/583)  (2/2) N/A
Spleen 2 No  (3/583) N/A
Stomach 2 No  (13/583) N/A
Striatum 2 No  (3/583) N/A
Testis 2 No  (6/583)  (1/2) N/A
Thymus 2 No  (1/583)  (1/2) N/A
Thyroid gland 2 No  (17/583) N/A
Trachea 2 No  (3/583)  (2/2) N/A
Uterus 2 No  (1/2) N/A
White adipose tissue 2 No N/A
LacZ Wholemount Images
LacZ Section Images
LacZ Section Images
Setdb1tm1a(EUCOMM)Wtsi
brain, HET, Female, WTSI
Setdb1tm1a(EUCOMM)Wtsi
ovary, HET, Female, WTSI
Setdb1tm1a(EUCOMM)Wtsi
urinary bladder, lower urinary tract, HET, Female, WTSI
Setdb1tm1a(EUCOMM)Wtsi
thymus, HET, Female, WTSI
Setdb1tm1a(EUCOMM)Wtsi
parathyroid gland, HET, Female, WTSI

View all 18 images

Setdb1tm1a(EUCOMM)Wtsi
ovary, HET, Female, WTSI
Setdb1tm1a(EUCOMM)Wtsi
urinary bladder, lower urinary tract, HET, Female, WTSI
Setdb1tm1a(EUCOMM)Wtsi
thymus, HET, Female, WTSI
Setdb1tm1a(EUCOMM)Wtsi
liver, HET, Female, WTSI
Setdb1tm1a(EUCOMM)Wtsi
stomach, HET, Female, WTSI

View all 13 images

Setdb1tm1a(EUCOMM)Wtsi
liver, HET, Female, WTSI
Setdb1tm1a(EUCOMM)Wtsi
stomach, HET, Female, WTSI
Setdb1tm1a(EUCOMM)Wtsi
small intestine, HET, Female, WTSI
Setdb1tm1a(EUCOMM)Wtsi
brain, HET, Female, WTSI
Setdb1tm1a(EUCOMM)Wtsi
peripheral nervous system, pituitary gland, HET, Male, WTSI
Setdb1tm1a(EUCOMM)Wtsi
spinal cord, HET, Male, WTSI
Setdb1tm1a(EUCOMM)Wtsi
urinary bladder, lower urinary tract, HET, Female, WTSI
Setdb1tm1a(EUCOMM)Wtsi
kidney, HET, Female, WTSI
Setdb1tm1a(EUCOMM)Wtsi
kidney, HET, Male, WTSI
Setdb1tm1a(EUCOMM)Wtsi
parathyroid gland, HET, Female, WTSI
Setdb1tm1a(EUCOMM)Wtsi
adrenal gland, HET, Male, WTSI
Setdb1tm1a(EUCOMM)Wtsi
ovary, HET, Female, WTSI
Setdb1tm1a(EUCOMM)Wtsi
testis, HET, Male, WTSI
Setdb1tm1a(EUCOMM)Wtsi
heart, HET, Female, WTSI
Setdb1tm1a(EUCOMM)Wtsi
thymus, HET, Female, WTSI
Setdb1tm1a(EUCOMM)Wtsi
skin, HET, Female, WTSI
Setdb1tm1a(EUCOMM)Wtsi
skeletal muscle tissue, HET, Female, WTSI
Setdb1tm1a(EUCOMM)Wtsi
lung, HET, Male, WTSI
No Embryo expression data was found for this gene.

 Associated Images

thumbnail
Histopathology
6 Images
Legacy Phenotype Associated Images
Setdb1tm1a(EUCOMM)Wtsi
body, HET, Male, WTSI
Setdb1tm1a(EUCOMM)Wtsi
body, WT, Female, WTSI
Setdb1tm1a(EUCOMM)Wtsi
head, WT, Female, WTSI
Setdb1tm1a(EUCOMM)Wtsi
head, WT, Female, WTSI
Setdb1tm1a(EUCOMM)Wtsi
body, WT, Female, WTSI

View all 109 images

Setdb1tm1a(EUCOMM)Wtsi
back skin, HET, Female, WTSI
Setdb1tm1a(EUCOMM)Wtsi
back skin, HET, Female, WTSI

 Disease Models

No associations by disease annotation and gene orthology found.
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 Histopathology

Phenotype Allele Zygosity Sex Life Stage
Lymph node - neoplasm Setdb1tm1a(EUCOMM)Wtsi HET Early adult
Lymph node - hyperplasia Setdb1tm1a(EUCOMM)Wtsi HET Early adult

 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Setdb1tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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