Gene: Mcam

Name
melanoma cell adhesion molecule
MGI ID
MGI:1933966
Synonyms
1-gicerin CD146 s-gicerin Muc18 s-endo
Viability
Homozygous - Viable
Other links
View data by physiological system
Significant
Not Significant
Not tested

Filtered by: all phenotypes

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Allele Center Procedure / Parameter Zygosity Mutants Statistical
Method
P Value Status
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Tail - thickness HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Forelimb digit - size HOM 8f:7m Fisher Exact Test framework 1.00 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Coat - hair distribution - back HOM 8f:7m Fisher Exact Test framework 1.00 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Forelimb nail - shape HOM 8f:7m Fisher Exact Test framework 1.00 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Hematology / Monocyte differential count HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.221 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Electrocardiogram (ECG) / RR HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.138 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Head bobbing HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Skin texture - whole body HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Trunk curl HOM 8f:7m Fisher Exact Test framework 1.00 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Body Composition (DEXA lean/fat) / Lean/Body weight HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.156 Success
Mcamtm1.1(KOMP)Wtsi UC Davis X-ray / Number of thoracic vertebrae HOM 5f:5m Not processed 1.00 FAILED - No variability in dependent variable 'IMPC_XRY_014_001'.
Mcamtm1.1(KOMP)Wtsi UC Davis X-ray / Number of ribs right HOM 5f:5m Not processed 1.00 FAILED - No variability in dependent variable 'IMPC_XRY_008_001'.
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Skin texture - ear HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Mcamtm1.1(KOMP)Wtsi UC Davis Hematology / Mean cell hemoglobin concentration HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.248 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Open Field / Distance travelled - total HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0655 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Snout size HOM 8f:7m Fisher Exact Test framework 1.00 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Electrocardiogram (ECG) / PR HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.523 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Auditory Brain Stem Response / Click-evoked ABR threshold HOM 2f:2m 0.616 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Auditory Brain Stem Response / 24kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Genitalia - size HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Mcamtm1.1(KOMP)Wtsi UC Davis Open Field / Periphery permanence time HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.174 Success
Mcamtm1.1(KOMP)Wtsi UC Davis X-ray / Radius HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Forelimb nail - length HOM 8f:7m Fisher Exact Test framework 1.00 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Electrocardiogram (ECG) / HR HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.165 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Intraperitoneal glucose tolerance test (IPGTT) / Initial response to glucose challenge HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.887 Success
Mcamtm1.1(KOMP)Wtsi UC Davis X-ray / Fibula HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Mcamtm1.1(KOMP)Wtsi UC Davis Hematology / Eosinophil differential count HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.114 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Open Field / Percentage center time HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.173 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Hematology / Mean platelet volume HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.287 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Auditory Brain Stem Response / 6kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Mcamtm1.1(KOMP)Wtsi UC Davis X-ray / Shape of vertebrae HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Aggression HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Mcamtm1.1(KOMP)Wtsi UC Davis Body Composition (DEXA lean/fat) / Body length HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.289 Success
Mcamtm1.1(KOMP)Wtsi UC Davis X-ray / Brachydactyly HOM 5f:5m Fisher Exact Test framework 1.00 Success
Mcamtm1.1(KOMP)Wtsi UC Davis X-ray / Pelvis HOM 5f:5m Fisher Exact Test framework 1.00 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Vibrissae - presence HOM 8f:7m Fisher Exact Test framework 1.00 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Grip Strength / Forelimb grip strength measurement mean HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0210 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Startle response HOM 8f:7m Fisher Exact Test framework 1.00 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Hindlimbs - shape HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Lower teeth appearance HOM 8f:7m Fisher Exact Test framework 1.00 Success
Mcamtm1.1(KOMP)Wtsi UC Davis X-ray / Scapulae HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Mcamtm1.1(KOMP)Wtsi UC Davis Eye Morphology / Lens Opacity HOM 8f:7m Fisher Exact Test framework 1.00 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Skin texture - back paws HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Forelimbs - shape HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Forelimb digit - shape HOM 8f:7m Fisher Exact Test framework 1.00 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Hematology / Mean cell volume HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0845 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Coat - color - back HOM 8f:7m Fisher Exact Test framework 1.00 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Open Field / Periphery distance travelled HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0321 Success
Mcamtm1.1(KOMP)Wtsi UC Davis X-ray / Femur HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Mcamtm1.1(KOMP)Wtsi UC Davis Eye Morphology / Cornea HOM 8f:7m Fisher Exact Test framework 0.00952 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Eye Morphology / Retina (combined) HOM 8f:7m Not processed Success
Mcamtm1.1(KOMP)Wtsi UC Davis Open Field / Center permanence time HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.173 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Auditory Brain Stem Response / 12kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Mcamtm1.1(KOMP)Wtsi UC Davis X-ray / Zygomatic bone HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Hindpaw - size HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Mcamtm1.1(KOMP)Wtsi UC Davis Hematology / Basophil cell count HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0937 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Body Composition (DEXA lean/fat) / Bone Mineral Density (excluding skull) HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0608 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Upper lip morphology HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Locomotor activity HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0240 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Hematology / Red blood cell count HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.730 Success
Mcamtm1.1(KOMP)Wtsi UC Davis X-ray / Shape of ribs HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Contact righting HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Mcamtm1.1(KOMP)Wtsi UC Davis Hematology / Hematocrit HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0743 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Skin color - ear HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Hindlimb nail - number HOM 8f:7m Fisher Exact Test framework 1.00 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Grip Strength / Forelimb and hindlimb grip strength normalised against body weight HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.642 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - head HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Skin texture - tail HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Vibrissae - appearance HOM 8f:7m Fisher Exact Test framework 1.00 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Intraperitoneal glucose tolerance test (IPGTT) / Area under glucose response curve HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.116 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Coat - color - abdomen HOM 8f:7m Fisher Exact Test framework 1.00 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1 HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0103 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Eye Morphology / Retinal Blood Vessels HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Mcamtm1.1(KOMP)Wtsi UC Davis Body Composition (DEXA lean/fat) / Fat mass HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0558 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3 HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.436 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Auditory Brain Stem Response / 30kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Hindpaw - shape HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Mcamtm1.1(KOMP)Wtsi UC Davis X-ray / Mandibles HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Mcamtm1.1(KOMP)Wtsi UC Davis Hematology / Neutrophil cell count HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.287 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Tremor HOM 8f:7m Fisher Exact Test framework 1.00 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Viability Primary Screen / Outcome HOM 54f:61m Supplied as data Success
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Genitalia - morphology HOM 8f:7m Fisher Exact Test framework 1.00 Success
Mcamtm1.1(KOMP)Wtsi UC Davis X-ray / Humerus HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Skin color - back paws HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Limb grasp HOM 8f:7m Fisher Exact Test framework 0.117 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Hematology / Lymphocyte cell count HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.940 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Head morphology HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Mcamtm1.1(KOMP)Wtsi UC Davis Electrocardiogram (ECG) / ST HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.201 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Skin color - whole body HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Mcamtm1.1(KOMP)Wtsi UC Davis Indirect Calorimetry / Respiratory Exchange Ratio HOM 0f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.417 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Upper teeth appearance HOM 8f:7m Fisher Exact Test framework 1.00 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Open Field / Center distance travelled HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.201 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Auditory Brain Stem Response / 18kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Mcamtm1.1(KOMP)Wtsi UC Davis X-ray / Number of digits HOM 5f:5m Not processed 1.00 FAILED - No variability in dependent variable 'IMPC_XRY_028_001'.
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Coat - hair distribution - abdomen HOM 8f:7m Fisher Exact Test framework 1.00 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Coat - color pattern - head HOM 8f:7m Fisher Exact Test framework 1.00 Success
Mcamtm1.1(KOMP)Wtsi UC Davis X-ray / Clavicle HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Genitalia - presence HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Mcamtm1.1(KOMP)Wtsi UC Davis X-ray / Number of lumbar vertebrae HOM 5f:5m Not processed 1.00 FAILED - No variability in dependent variable 'IMPC_XRY_015_001'.
Mcamtm1.1(KOMP)Wtsi UC Davis Hematology / Platelet count HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0368 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Activity (body position) HOM 8f:7m Fisher Exact Test framework 1.00 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Hindlimb nail - shape HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Mcamtm1.1(KOMP)Wtsi UC Davis X-ray / Ulna HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Coat - hair distribution - head HOM 8f:7m Fisher Exact Test framework 1.00 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Hindlimb digit - size HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Hindlimb digit - number HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Mcamtm1.1(KOMP)Wtsi UC Davis X-ray / Digit integrity HOM 5f:5m Fisher Exact Test framework 1.00 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Tail - length HOM 8f:7m Fisher Exact Test framework 1.00 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Hematology / Monocyte cell count HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.231 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Open Field / Number of rears - total HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.000847 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Unexpected behaviors HOM 8f:7m Fisher Exact Test framework 1.00 Success
Mcamtm1.1(KOMP)Wtsi UC Davis X-ray / Teeth HOM 5f:5m Fisher Exact Test framework 1.00 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Skin texture - snout HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Mcamtm1.1(KOMP)Wtsi UC Davis X-ray / Number of ribs left HOM 5f:5m Not processed 1.00 FAILED - No variability in dependent variable 'IMPC_XRY_009_001'.
Mcamtm1.1(KOMP)Wtsi UC Davis Body Composition (DEXA lean/fat) / Fat/Body weight HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0241 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Hindlimbs - position HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Hindlimbs - size HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Mcamtm1.1(KOMP)Wtsi UC Davis X-ray / Number of cervical vertebrae HOM 5f:5m Not processed 1.00 FAILED - No variability in dependent variable 'IMPC_XRY_013_001'.
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Skin texture - front paws HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Mcamtm1.1(KOMP)Wtsi UC Davis Body Composition (DEXA lean/fat) / Bone Area HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0462 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Coat - color - head HOM 8f:7m Fisher Exact Test framework 1.00 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Hematology / Mean corpuscular hemoglobin HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.769 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Forelimbs - size HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Hindlimb digit - shape HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Mcamtm1.1(KOMP)Wtsi UC Davis Intraperitoneal glucose tolerance test (IPGTT) / Fasted blood glucose concentration HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.660 Success
Mcamtm1.1(KOMP)Wtsi UC Davis X-ray / Fusion of vertebrae HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Forepaw - size HOM 8f:7m Fisher Exact Test framework 1.00 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Tail - morphology HOM 8f:7m Fisher Exact Test framework 1.00 Success
Mcamtm1.1(KOMP)Wtsi UC Davis X-ray / Tibia HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Coat - color pattern - abdomen HOM 8f:7m Fisher Exact Test framework 0.187 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Forelimbs - position HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Hindlimb nail - length HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Mcamtm1.1(KOMP)Wtsi UC Davis X-ray / Fusion of ribs HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Mcamtm1.1(KOMP)Wtsi UC Davis Hematology / Eosinophil cell count HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.128 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Vocalization HOM 8f:7m Fisher Exact Test framework 0.000217 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Body Composition (DEXA lean/fat) / BMC/Body weight HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0340 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Grip Strength / Forelimb and hindlimb grip strength measurement mean HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.721 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Hematology / Hemoglobin HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.546 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Lower lip morphology HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Mcamtm1.1(KOMP)Wtsi UC Davis Hematology / Basophil differential count HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0276 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Skin color - front paws HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Mcamtm1.1(KOMP)Wtsi UC Davis Open Field / Whole arena resting time HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.360 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - abdomen HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Mcamtm1.1(KOMP)Wtsi UC Davis X-ray / Syndactylism HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Teeth presence HOM 8f:7m Fisher Exact Test framework 1.00 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Eye Morphology / Lens HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Mcamtm1.1(KOMP)Wtsi UC Davis Grip Strength / Forelimb grip strength normalised against body weight HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0185 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Head size HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Coat - color pattern - back HOM 8f:7m Fisher Exact Test framework 1.00 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Eye Morphology / Optic Disc HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Mcamtm1.1(KOMP)Wtsi UC Davis Open Field / Center average speed HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0114 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Eye Morphology / Retinal Blood Vessels Structure HOM 8f:7m Fisher Exact Test framework 1.00 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Fertility of Homozygous Knock-out Mice / Gross Findings Female HOM f:m Supplied as data Success
Mcamtm1.1(KOMP)Wtsi UC Davis X-ray / Joints HOM 5f:5m Fisher Exact Test framework 1.00 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Heart Weight / Heart weight HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0565 Success
Mcamtm1.1(KOMP)Wtsi UC Davis X-ray / Skull shape HOM 5f:5m Fisher Exact Test framework 1.00 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Forepaw - shape HOM 8f:7m Fisher Exact Test framework 1.00 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Forelimb nail - number HOM 8f:7m Fisher Exact Test framework 1.00 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Body Composition (DEXA lean/fat) / Bone Mineral Content (excluding skull) HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.108 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Hematology / Neutrophil differential count HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.341 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Gait HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Mcamtm1.1(KOMP)Wtsi UC Davis Electrocardiogram (ECG) / QRS HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.538 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Hematology / Red blood cell distribution width HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.652 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Ears HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Skin color - snout HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Forelimb digit - number HOM 8f:7m Fisher Exact Test framework 1.00 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - back HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Tail - presence HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Mcamtm1.1(KOMP)Wtsi UC Davis Insulin Blood Level / Insulin HOM 7f:6m Mixed Model framework, generalized least squares, equation withoutWeight 0.0364 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2 HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.323 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.128 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Open Field / Periphery average speed HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0491 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Fertility of Homozygous Knock-out Mice / Gross Findings Male HOM f:m Supplied as data Success
Mcamtm1.1(KOMP)Wtsi UC Davis X-ray / Processes on vertebrae HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Mcamtm1.1(KOMP)Wtsi UC Davis X-ray / Tibia length HOM 5f:5m Mixed Model framework, generalized least squares, equation withWeight 0.580 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Body Composition (DEXA lean/fat) / Lean mass HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.606 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Open Field / Whole arena average speed HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0655 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Eye Morphology / Corneal opacity HOM 8f:7m Fisher Exact Test framework 0.293 Success
Mcamtm1.1(KOMP)Wtsi UC Davis X-ray / Maxilla/Pre-maxilla HOM 5f:5m Fisher Exact Test framework 1.00 Success
Mcamtm1.1(KOMP)Wtsi UC Davis X-ray / Number of pelvic vertebrae HOM 5f:5m Not processed 1.00 FAILED - No variability in dependent variable 'IMPC_XRY_016_001'.
Mcamtm1.1(KOMP)Wtsi UC Davis Hematology / Lymphocyte differential count HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0697 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Hematology / White blood cell count HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.627 Success
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Skin color - tail HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Mcamtm1.1(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Mouth morphology HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 4 No  (2/584) N/A
Aorta 4 No  (4/4) N/A
Blood 4 No N/A
Bone marrow 4 No N/A
Brain 4 No  (2/4) N/A
Brainstem 4 No N/A
Brown adipose tissue 4 No  (1/4) N/A
Cartilage tissue 4 No N/A
Cecum 4 No  (12/383)  (2/4) N/A
Cerebellum 4 No  (4/4) N/A
Cerebral cortex 4 No N/A
Chest bone 4 No  (2/4) N/A
Colon 4 No  (12/127)  (3/4) N/A
Diaphragm 4 No  (2/4) N/A
Duodenum 4 No  (2/127)  (2/4) N/A
Epididymis 4 No  (18/134)  (2/4) N/A
Esophagus 4 No  (7/415)  (1/4) N/A
Eye 4 No N/A
Gall bladder 4 No  (2/4) N/A
Gonadal fat pad 4 No  (3/4) N/A
Harderian gland 4 No N/A
Heart 4 No N/A
Hindlimb 4 No N/A
Hippocampus 4 No N/A
Hypothalamus 4 No N/A
Ileum 4 No  (14/127)  (3/4) N/A
Jejunum 4 No  (6/127)  (2/4) N/A
Kidney 4 No  (18/584)  (2/4) N/A
Large intestine 4 No  (10/584) N/A
Liver 4 No N/A
Lower urinary tract 4 No N/A
Lung 4 No  (3/4) N/A
Lymph node 4 No N/A
Mammary gland 4 No N/A
Mesenteric adipose tissue 4 No  (2/4) N/A
Mesenteric lymph node 4 No N/A
Midbrain 4 No  (4/4) N/A
Olfactory lobe 4 No  (3/4) N/A
Ovary 4 No  (1/584)  (1/4) N/A
Oviduct 4 No  (2/4) N/A
Pancreas 4 No  (5/584)  (2/4) N/A
Parathyroid gland 4 No N/A
Parotid gland 4 No N/A
Penis 4 No  (2/4) N/A
Peripheral nervous system 4 No N/A
Peyer's patch 4 No N/A
Pituitary gland 4 No N/A
Prostate gland 4 No  (12/584) N/A
Quadriceps 4 No  (4/4) N/A
Sciatic nerve 4 No N/A
Skeletal muscle 4 No N/A
Skin 4 No  (1/4) N/A
Small intestine 4 No  (9/584) N/A
Spinal cord 4 No  (4/4) N/A
Spleen 4 No  (2/584)  (4/4) N/A
Stomach 4 No  (12/584)  (4/4) N/A
Stomach pyloric region 4 No N/A
Striatum 4 No N/A
Sublingual gland 4 No N/A
Submandibular gland 4 No  (2/132) N/A
Testis 4 No  (2/584)  (2/4) N/A
Thymus 4 No N/A
Thyroid gland 4 No  (15/584)  (1/4) N/A
Tongue 4 No  (5/127)  (3/4) N/A
Trachea 4 No  (2/4) N/A
Trigeminal V nerve 4 No  (2/4) N/A
Urinary bladder 4 No  (4/4) N/A
Uterus 4 No  (2/4) N/A
Vagina 4 No  (1/4) N/A
Vas deferens 4 No  (15/388)  (2/4) N/A
Vascular system 4 No N/A
Vesicular gland 4 No  (1/4) N/A
White adipose tissue 4 No N/A
No Embryo expression data was found for this gene.

 Associated Images

X-ray: XRay Images Lateral Orientation
20 Images
X-ray: XRay Images Dorso Ventral
40 Images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Mcamtm1(KOMP)Wtsi Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Mcamtm1.1(KOMP)Wtsi Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice, Tissue
Mcamtm443744(L1L2_GT1_LF2A_LacZ_BetactP_neo) Targeting vectors

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