Not currently registered for phenotyping at IMPC
Phenotyping is currently not planned for a knockout strain of this gene.
Gene Summary
IMPC Data Collections
- No Body Weight Data
- No Embryo Imaging Data
- No Viability Data
Phenotyping is currently not planned for a knockout strain of this gene.
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
The table below shows human diseases predicted to be associated to Cacng8 by phenotypic similarity.
Disease | Similarity of phenotypes |
Matching phenotypes | Source |
---|---|---|---|
Childhood Disintegrative Disorder | Social and occupational deterioration, Dementia, Abnormal emotion, Progressive language deteriora... | ORPHA:168782 | |
Childhood Absence Epilepsy | Abnormal social behavior, Attention deficit hyperactivity disorder, Depression | ORPHA:64280 | |
Early-Onset Autosomal Dominant Alzheimer Disease | Confusion, Dementia, Semantic dementia, Memory impairment, Abnormal social behavior | ORPHA:1020 | |
Metachromatic Leukodystrophy, Juvenile Form | Emotional lability, Abnormal social behavior, Progressive psychomotor deterioration, Short attent... | ORPHA:309263 | |
Metachromatic Leukodystrophy, Adult Form | Short attention span, Progressive psychomotor deterioration, Emotional lability, Depression, Deme... | ORPHA:309271 | |
Progressive Supranuclear Palsy | Abnormal synaptic transmission | ORPHA:683 |
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