Dbr1 | debranching RNA lariats 1

Physiological systems

19 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Vision/eye Mortality/aging Renal/urinary system

15 No significant impact

5 Not tested

Gene metrics:4Significant phenotypes
2Associated diseases
Expression examined in:48Adult tissues
25Embryo tissues

Phenotypes

abnormal lens morphology1 supporting datasetDbr1tm1.1(KOMP)VlcgheterozygoteEarly adult5.78x10-7 
decreased urine magnesium level1 supporting datasetDbr1tm1.1(KOMP)VlcgheterozygoteEarly adult1.81x10-61 
preweaning lethality, complete penetrance1 supporting datasetDbr1tm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
embryonic lethality prior to organogenesis1 supporting datasetDbr1tm1.1(KOMP)VlcghomozygoteE9.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
Download data as:  










* This parameter was manually assessed for significance.
Download data as:  

lacZ Expression

adrenal glandheterozygoteSection images
100% (2/2)0.7% (4/570)
aortaheterozygoteSection images
100% (2/2)0.19% (1/533)
brainheterozygoteSection images
100% (2/2)0.86% (5/579)
brainstemheterozygoteSection images
100% (2/2)0.41% (2/490)
brown adipose tissueheterozygoteSection images
100% (2/2)0% (0/588)
cartilage tissueheterozygoteSection images
100% (2/2)0.22% (1/454)
cerebellumheterozygoteSection images
100% (2/2)0.56% (3/532)
cerebral cortexheterozygoteSection images
100% (2/2)0.41% (2/491)
epididymisheterozygoteSection images
100% (1/1)87.5% (21/24)
esophagusheterozygoteSection images
100% (2/2)1.67% (7/419)
Download adult data as:  
Rows per page: 

Histopathology

IMPC related publications

Loading...

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

Dbr1tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Dbr1tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Dbr1tm78661(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter