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Gene: Qtrt1 MGI:1931441

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Not currently registered for phenotyping at IMPC

Phenotyping is currently not planned for a knockout strain of this gene.

Gene Summary

Name:
queuine tRNA-ribosyltransferase catalytic subunit 1
Synonyms:
2610028E17Rik,  tRNA-guanine transglycosylase,  Tgt

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IMPC Data Collections

  • No Body Weight Data
  • No Embryo Imaging Data
  • No Viability Data

IMPC Phenotype Summary

Significant
Not Significant
Not tested

View all our phenotype data below

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Phenotype associated images not available

Human diseases caused by Qtrt1 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

No human diseases associated to this gene by orthology or annotation.

The table below shows human diseases predicted to be associated to Qtrt1 by phenotypic similarity.

Disease Similarity of
phenotypes		 Matching phenotypes Source
Tyrosinosis
Hypertyrosinemia OMIM:276800
Tyrosinemia, Type Ii
Hypertyrosinemia OMIM:276600
Tyrosinemia, Type Iii
Hypertyrosinemia OMIM:276710
Hawkinsinuria
Hypertyrosinemia OMIM:140350
Histidinemia
Histidinuria, Hyperhistidinemia OMIM:235800
Citrullinemia, Type Ii, Neonatal-Onset
Hypertyrosinemia OMIM:605814
Mitochondrial Dna Depletion Syndrome 15 (Hepatocerebral Type)
Hypertyrosinemia OMIM:617156
Tyrosinemia, Type I
Hypertyrosinemia OMIM:276700
Mitochondrial Complex Iii Deficiency, Nuclear Type 1
Hypertyrosinemia, Aminoaciduria OMIM:124000
Neonatal Intrahepatic Cholestasis Due To Citrin Deficiency
Hypertyrosinemia ORPHA:247598

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Qtrt1

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Qtrt1.

No publications found that use IMPC mice or data for Qtrt1.

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