Not currently registered for phenotyping at IMPC
Phenotyping is currently not planned for a knockout strain of this gene.
Gene Summary
IMPC Data Collections
- No Body Weight Data
- No Embryo Imaging Data
- No Viability Data
Phenotyping is currently not planned for a knockout strain of this gene.
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
The table below shows human diseases predicted to be associated to Or8a1b by phenotypic similarity.
Disease | Similarity of phenotypes |
Matching phenotypes | Source |
---|---|---|---|
Leber Congenital Amaurosis 10 | Hyposmia | OMIM:611755 | |
Hypogonadotropic Hypogonadism 17 With Or Without Anosmia | Hyposmia | OMIM:615266 | |
Anosmia For Butyl Mercaptan | Anosmia | OMIM:270350 | |
Isovaleric Acid, Inability To Smell | Anosmia | OMIM:243450 | |
Anosmia, Isolated Congenital, X-Linked | Anosmia | OMIM:301700 | |
Anosmia, Isolated Congenital | Anosmia | OMIM:107200 | |
Anosmia For Isobutyric Acid | Partial anosmia | OMIM:207000 | |
Hypogonadotropic Hypogonadism 21 With Or Without Anosmia | Hyposmia | OMIM:615271 | |
Musk, Inability To Smell | Anosmia | OMIM:254150 | |
Thumb Agenesis, Short Stature, And Immunodeficiency | Anosmia | OMIM:274190 | |
Aural Atresia, Congenital | Hyposmia | OMIM:607842 | |
Hypogonadotropic Hypogonadism 7 With Or Without Anosmia | Abnormality of the sense of smell | OMIM:146110 | |
Arrhinia-Choanal Atresia-Microphthalmia Syndrome | Aplasia/Hypoplasia involving the nose, Choanal atresia, Abnormality of the sense of smell | ORPHA:1135 | |
Apnea, Obstructive Sleep | Anosmia | OMIM:107650 | |
Hypogonadotropic Hypogonadism 9 With Or Without Anosmia | Hyposmia, Anosmia, Bifid nose | OMIM:614838 | |
Hypogonadotropic Hypogonadism 20 With Or Without Anosmia | Anosmia | OMIM:615270 | |
Hypogonadotropic Hypogonadism 14 With Or Without Anosmia | Anosmia | OMIM:614858 | |
Chondrodysplasia Punctata 1, X-Linked Recessive | Short nasal septum, Anosmia, Depressed nasal bridge, Short nose | OMIM:302950 | |
Leukoencephalopathy With Dystonia And Motor Neuropathy | Hyposmia | OMIM:613724 | |
Hypogonadotropic Hypogonadism 5 With Or Without Anosmia | Anosmia | OMIM:612370 | |
Body Mass Index Quantitative Trait Locus 19 | Hyposmia, Anosmia | OMIM:617885 | |
Hypogonadotropic Hypogonadism 18 With Or Without Anosmia | Anosmia | OMIM:615267 | |
Hypogonadotropic Hypogonadism 6 With Or Without Anosmia | Hyposmia, Anosmia | OMIM:612702 | |
Hypogonadotropic Hypogonadism 4 With Or Without Anosmia | Hyposmia, Anosmia | OMIM:610628 | |
Hypogonadotropic Hypogonadism 2 With Or Without Anosmia | Hyposmia, Anosmia, Agenesis of corpus callosum, Choanal atresia | OMIM:147950 | |
Solitary Median Maxillary Central Incisor | Abnormal nasopharynx morphology, Midnasal stenosis, Choanal atresia, Anosmia, Holoprosencephaly, ... | OMIM:147250 | |
Gorlin Syndrome | Hydrocephalus, Wide nasal bridge, Abnormality of the sense of smell | ORPHA:377 | |
Peroxisome Biogenesis Disorder 9B | Anosmia, Total anosmia | OMIM:614879 | |
Hypogonadotropic Hypogonadism 3 With Or Without Anosmia | Hyposmia, Anosmia | OMIM:244200 | |
Hydrolethalus | Anencephaly, Hydrocephalus, Agenesis of corpus callosum, Abnormality of the sense of smell | ORPHA:2189 | |
Hyperostosis Cranialis Interna | Hyposmia, Anosmia | OMIM:144755 | |
Bardet-Biedl Syndrome 19 | Hyposmia | OMIM:615996 | |
Indifference To Pain, Congenital, Autosomal Recessive | Hyposmia, Anosmia | OMIM:243000 | |
Hypogonadotropic Hypogonadism 15 With Or Without Anosmia | Anosmia | OMIM:614880 | |
Hypogonadotropic Hypogonadism 16 With Or Without Anosmia | Hyposmia, Anosmia | OMIM:614897 | |
Blepharophimosis With Ptosis, Syndactyly, And Short Stature | Anosmia, Wide nasal bridge | OMIM:210745 | |
Hypogonadotropic Hypogonadism 10 With Or Without Anosmia | Anosmia | OMIM:614839 | |
Hypogonadotropic Hypogonadism 13 With Or Without Anosmia | Anosmia | OMIM:614842 | |
Blepharophimosis-Ptosis-Esotropia-Syndactyly-Short Stature Syndrome | Anosmia | ORPHA:2057 | |
Huntington Disease | Abnormality of the sense of smell | ORPHA:399 | |
Hypogonadotropic Hypogonadism 25 With Anosmia | Anosmia | OMIM:618841 | |
Ventricular Extrasystoles With Syncopal Episodes-Perodactyly-Robin Sequence Syndrome | Abnormality of the sense of smell | ORPHA:3201 | |
Marcus-Gunn Syndrome | Choanal atresia, Abnormality of the sense of smell | ORPHA:91412 | |
Brachytelephalangy-Dysmorphism-Kallmann Syndrome | Abnormal nostril morphology, Short nose, Anosmia | ORPHA:1295 | |
Ciliary Dyskinesia, Primary, 1 | Communicating hydrocephalus, Nasal polyposis, Anosmia, Chronic rhinitis | OMIM:244400 | |
Kleine-Levin Syndrome | Parosmia | ORPHA:33543 | |
Bardet-Biedl Syndrome 17 | Hyposmia, Anosmia | OMIM:615994 | |
Hypogonadotropic Hypogonadism 22 With Or Without Anosmia | Anosmia | OMIM:616030 | |
Johnson Neuroectodermal Syndrome | Bulbous nose, Anosmia, Choanal atresia | ORPHA:2316 | |
Parkinson Disease 8, Autosomal Dominant | Hyposmia | OMIM:607060 | |
Hypogonadotropic Hypogonadism 12 With Or Without Anosmia | Anosmia | OMIM:614841 | |
Kufor-Rakeb Syndrome | Hyposmia, Anosmia | OMIM:606693 | |
Hypogonadotropic Hypogonadism 1 With Or Without Anosmia | Hyposmia, Anosmia | OMIM:308700 | |
Hypogonadotropic Hypogonadism 8 With Or Without Anosmia | Anosmia | OMIM:614837 | |
Refsum Disease, Classic | Anosmia | OMIM:266500 | |
Neuropathy, Hereditary Motor And Sensory, Type Via, With Optic Atrophy | Anosmia | OMIM:601152 | |
Hypogonadotropic Hypogonadism 23 With Or Without Anosmia | Abnormality of the sense of smell | OMIM:228300 | |
Polyendocrine-Polyneuropathy Syndrome | Abnormality of the sense of smell | OMIM:616113 | |
8Q21.11 Microdeletion Syndrome | Wide nose, Underdeveloped nasal alae, Abnormality of the sense of smell | ORPHA:284160 | |
Septo-Optic Dysplasia Spectrum | Anosmia, Agenesis of corpus callosum | ORPHA:3157 | |
Kallmann Syndrome With Spastic Paraplegia | Anosmia | OMIM:308750 | |
Neuropathy, Hereditary Sensory And Autonomic, Type Viii | Hyposmia | OMIM:616488 | |
Refsum Disease | Anosmia | ORPHA:773 | |
Holoprosencephaly | Encephalocele, Aplasia/Hypoplasia involving the nose, Anteverted nares, Choanal atresia, Hydrocep... | ORPHA:2162 | |
Acro-Renal-Mandibular Syndrome | Abnormality of the sense of smell | ORPHA:958 | |
Isolated Follicle Stimulating Hormone Deficiency | Anosmia | ORPHA:52901 | |
Campomelic Dysplasia | Depressed nasal bridge, Abnormality of the sense of smell | ORPHA:140 | |
Hyposmia-Nasal And Ocular Hypoplasia-Hypogonadotropic Hypogonadism Syndrome | Hyposmia, Anosmia, Absent nares, Single naris | ORPHA:2250 | |
Young-Onset Parkinson Disease | Hyposmia | ORPHA:2828 | |
Kallmann Syndrome | Hyposmia, Anosmia | ORPHA:478 | |
Kallmann Syndrome-Heart Disease Syndrome | Partial anosmia, Total anosmia | ORPHA:2326 | |
Moebius Syndrome | Abnormality of the sense of smell | ORPHA:570 | |
8P11.2 Deletion Syndrome | Anosmia, Depressed nasal bridge | ORPHA:251066 | |
Superficial Siderosis | Anosmia, Partial anosmia | ORPHA:247245 | |
Hereditary Late-Onset Parkinson Disease | Hyposmia | ORPHA:411602 | |
Meningioma | Hydrocephalus, Abnormality of the sense of smell | ORPHA:2495 | |
Waardenburg Syndrome, Type 2E | Anosmia | OMIM:611584 | |
Hypogonadotropic Hypogonadism 26 With Or Without Anosmia | Anosmia | OMIM:619718 | |
Waardenburg Syndrome, Type 4C | Anosmia | OMIM:613266 | |
Leopard Syndrome 1 | Hyposmia, Spina bifida occulta, Depressed nasal ridge | OMIM:151100 | |
Peripheral Demyelinating Neuropathy, Central Dysmyelination, Waardenburg Syndrome, And Hirschsprung Disease | Anosmia | OMIM:609136 | |
Wilson Disease | Hyposmia | OMIM:277900 | |
Intellectual Developmental Disorder With Impaired Language And Dysmorphic Facies | Hyposmia | OMIM:618653 | |
Bosma Arhinia Microphthalmia Syndrome | Anosmia, Choanal atresia, Aplasia of the nose | OMIM:603457 | |
Occipital Horn Syndrome | Abnormality of the sense of smell | ORPHA:198 | |
Amoebiasis Due To Free-Living Amoebae | Hyposmia | ORPHA:68 | |
Charge Syndrome | Depressed nasal bridge, Choanal atresia, Aqueductal stenosis, Anosmia, Holoprosencephaly | ORPHA:138 | |
Lacrimoauriculodentodigital Syndrome | Anosmia, Choanal atresia | ORPHA:2363 | |
Charge Syndrome | Anosmia, Choanal atresia, Holoprosencephaly | OMIM:214800 |
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