Gene: Myh10

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Name
myosin, heavy polypeptide 10, non-muscle
MGI ID
MGI:1930780
Synonyms
SMemb nonmuscle myosin heavy chain II-B nonmuscle myosin heavy chain IIB Myhn2 Fltn Fltn Myosin IIB Myhn-2 NMHC-B myosin IIB 5730504C04Rik NMHC II-B 9330167F11Rik
Embryo Screen
N/A
Other links
Expression & images (0) Disease models (0) Order (2)
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal skin coloration Myh10em1(IMPC)J HOM embryonic day 15.5 0.00
preweaning lethality, complete penetrance Myh10em1(IMPC)J HOM n/a 0.00
abnormal pericardium morphology Myh10em1(IMPC)J HOM embryonic day 12.5 0.00
hemorrhage Myh10em1(IMPC)J HOM embryonic day 15.5 0.00
hemorrhage Myh10em1(IMPC)J HOM embryonic day 12.5 0.00
abnormal placenta size Myh10em1(IMPC)J HOM embryonic day 15.5 0.00
cardiovascular system phenotype Myh10em1(IMPC)J HET postnatal 2.12×10-05
embryonic growth retardation Myh10em1(IMPC)J HOM embryonic day 12.5 0.00
improved glucose tolerance Myh10em1(IMPC)J HET postnatal 9.10×10-05
increased heart rate variability Myh10em1(IMPC)J HET postnatal 2.07×10-05
edema Myh10em1(IMPC)J HOM embryonic day 15.5 0.00

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 Expression

Expression data not available

 Associated Images

X-ray: XRay Images Skull Lateral Orientation
9 Images
X-ray: XRay Images Lateral Orientation
9 Images
Sleep Wake: Wake state (bmp file)
1 Images
X-ray: XRay Images Dorso Ventral
9 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
9 Images
X-ray: XRay Images Forepaw
9 Images
Gross Morphology Embryo E12.5
12 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

MGI Allele Allele Type Produced
Myh10em1(IMPC)J Indel causing a Frameshift Mutation Mice
Myh10tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells