Genes Phenotypes

Gene: Myh10

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Name
myosin, heavy polypeptide 10, non-muscle
MGI ID
MGI:1930780
Synonyms
SMemb nonmuscle myosin heavy chain II-B nonmuscle myosin heavy chain IIB Myhn2 Fltn Fltn Myosin IIB Myhn-2 NMHC-B myosin IIB 5730504C04Rik NMHC II-B 9330167F11Rik
Viability
Homozygous - Lethal
View
N/A
Other links
MGI   Ensembl  
Significant phenotypes (11) Measurements chart (195) All data table (497)
Expression & images (0) Disease models (0) Order (2)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal skin coloration Myh10em1(IMPC)J HOM embryonic day 15.5 0.00
preweaning lethality, complete penetrance Myh10em1(IMPC)J HOM n/a 0.00
hemorrhage Myh10em1(IMPC)J HOM embryonic day 15.5 0.00
abnormal placenta size Myh10em1(IMPC)J HOM embryonic day 15.5 0.00
hemorrhage Myh10em1(IMPC)J HOM embryonic day 12.5 0.00
cardiovascular system phenotype Myh10em1(IMPC)J HET postnatal 2.12×10-05
abnormal pericardium morphology Myh10em1(IMPC)J HOM embryonic day 12.5 0.00
improved glucose tolerance Myh10em1(IMPC)J HET postnatal 9.10×10-05
increased heart rate variability Myh10em1(IMPC)J HET postnatal 2.07×10-05
edema Myh10em1(IMPC)J HOM embryonic day 15.5 0.00
embryonic growth retardation Myh10em1(IMPC)J HOM embryonic day 12.5 0.00

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 Expression

Expression data not available

 Associated Images

X-ray: XRay Images Lateral Orientation
9 Images
X-ray: XRay Images Skull Lateral Orientation
9 Images
Gross Morphology Embryo E12.5
12 Images
X-ray: XRay Images Dorso Ventral
9 Images
X-ray: XRay Images Forepaw
9 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
9 Images
Sleep Wake: Wake state (bmp file)
1 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Myh10em1(IMPC)J Indel causing a Frameshift Mutation Mice
Myh10tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells