Genes Phenotypes

Gene: Myh10

Name
myosin, heavy polypeptide 10, non-muscle
MGI ID
MGI:1930780
Synonyms
SMemb nonmuscle myosin heavy chain II-B nonmuscle myosin heavy chain IIB Myhn2 Fltn Fltn Myosin IIB Myhn-2 NMHC-B myosin IIB 5730504C04Rik NMHC II-B 9330167F11Rik
Viability
Homozygous - Lethal
View
N/A
Other links
MGI   Ensembl  
Significant phenotypes (11) Measurements chart (193) All data table (496)
Expression & images (0) Disease models (0) Order (2)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
cardiovascular system phenotype Myh10em1(IMPC)J HET postnatal 2.12×10-05
edema Myh10em1(IMPC)J HOM embryonic day 15.5 0.00
increased heart rate variability Myh10em1(IMPC)J HET postnatal 2.07×10-05
embryonic growth retardation Myh10em1(IMPC)J HOM embryonic day 12.5 0.00
abnormal placenta size Myh10em1(IMPC)J HOM embryonic day 15.5 0.00
abnormal skin coloration Myh10em1(IMPC)J HOM embryonic day 15.5 0.00
hemorrhage Myh10em1(IMPC)J HOM embryonic day 12.5 0.00
abnormal pericardium morphology Myh10em1(IMPC)J HOM embryonic day 12.5 0.00
preweaning lethality, complete penetrance Myh10em1(IMPC)J HOM n/a 0.00
hemorrhage Myh10em1(IMPC)J HOM embryonic day 15.5 0.00
improved glucose tolerance Myh10em1(IMPC)J HET postnatal 9.10×10-05

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 Expression

Expression data not available

 Associated Images

X-ray: XRay Images Skull Lateral Orientation
9 Images
X-ray: XRay Images Dorso Ventral
9 Images
Sleep Wake: Wake state (bmp file)
1 Images
X-ray: XRay Images Lateral Orientation
9 Images
Gross Morphology Embryo E12.5
12 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
9 Images
X-ray: XRay Images Forepaw
9 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Myh10em1(IMPC)J Indel causing a Frameshift Mutation Mice
Myh10tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells