Genes Phenotypes

Gene: Tmem115

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Name
transmembrane protein 115
MGI ID
MGI:1930765
Synonyms
Pl6
Viability
Homozygous - Lethal
Embryo viewer
3D Imaging
Other links
MGI   Ensembl  
Significant phenotypes (7) Measurements chart (203) All data table (417)
Expression & images (30) Disease models (0) Order (2)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
decreased erythrocyte cell number Tmem115tm1(KOMP)Vlcg HET Early adult 4.82×10-07
decreased neutrophil cell number Tmem115tm1(KOMP)Vlcg HET Early adult 3.33×10-10
increased circulating creatinine level Tmem115tm1(KOMP)Vlcg HET Early adult 9.61×10-08
increased lymphocyte cell number Tmem115tm1(KOMP)Vlcg HET Early adult 3.97×10-07
edema Tmem115tm1.1(KOMP)Vlcg HET E15.5 0.00
edema Tmem115tm1.1(KOMP)Vlcg HOM E15.5 0.00
preweaning lethality, complete penetrance Tmem115tm1(KOMP)Vlcg HOM Early adult 0.00

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 Expression

IMPC lacZ Expression Data

No Adult expression data was found for this gene.
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2  (1/61)  (2/2) N/A
Brain 5  (6/504)  (2/6) N/A
Central nervous system ganglion 2  (1/70)  (2/2) N/A
Ear 5  (1/504)  (2/6) N/A
Embryo 5  (1/505)  (2/6) N/A
Eye 5  (1/504)  (2/6) N/A
Foot 5  (1/504)  (2/6) N/A
Forebrain 5  (1/504)  (2/6) N/A
Forelimb 5  (1/504)  (2/6) N/A
Gut 2  (1/56)  (2/2) N/A
Hand 5  (1/503)  (2/6) N/A
Head 5  (5/504)  (2/6) N/A
Heart 5  (1/504)  (2/6) N/A
Hindbrain 5  (6/504)  (2/6) N/A
Hindlimb 5  (1/503)  (2/6) N/A
Liver 5  (1/504)  (2/6) N/A
Lung 5  (1/500)  (2/6) N/A
Mandibular process 5  (1/504)  (2/6) N/A
Maxillary process 5  (1/504)  (2/6) N/A
Midbrain 5  (1/504)  (2/6) N/A
Nose 2  (1/70)  (2/2) N/A
Oral cavity 5  (1/504)  (2/6) N/A
2  (7/37)  (2/2) N/A
Skeleton 2  (1/70)  (2/2) N/A
Skin 5  (1/504)  (2/6) N/A
Spinal cord 2  (1/69)  (2/2) N/A
Tail 5  (1/504)  (2/6) N/A
Tail somite 5  (1/504)  (2/6) N/A
Trachea 2  (1/56)  (2/2) N/A
Urinary system 2  (1/56)  (2/2) N/A

 Associated Images

Embryo LacZ: LacZ images wholemount
24 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Tmem115tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Tmem115tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice

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