Gene: Srd5a3

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Name
steroid 5 alpha-reductase 3
MGI ID
MGI:1930252
Synonyms
1110025P14Rik D730040M03Rik Srd5a2l
View
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal neural tube closure Srd5a3tm1b(EUCOMM)Wtsi HET embryonic day 9.5 0.00
abnormal embryo turning Srd5a3tm1b(EUCOMM)Wtsi HOM embryonic day 9.5 0.00
abnormal embryo size Srd5a3tm1b(EUCOMM)Wtsi HOM embryonic day 9.5 0.00
embryonic growth retardation Srd5a3tm1b(EUCOMM)Wtsi HOM embryonic day 9.5 0.00
preweaning lethality, complete penetrance Srd5a3tm1b(EUCOMM)Wtsi HOM n/a 0.00
abnormal tail bud morphology Srd5a3tm1b(EUCOMM)Wtsi HOM embryonic day 9.5 0.00
abnormal heart morphology Srd5a3tm1b(EUCOMM)Wtsi HET embryonic day 9.5 0.00

Download data as:  TSV  XLS

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Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (2/2) N/A
Aorta 2 No  (2/2) N/A
Brain 2 No  (2/2) N/A
Brainstem 2 No  (2/2) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (2/2) N/A
Cerebellum 2 No  (2/2) N/A
Cerebral cortex 2 No  (2/2) N/A
Epididymis 2 No  (18/134)  (1/2) N/A
Esophagus 2 No  (7/415)  (2/2) N/A
Eye 2 No  (2/2) N/A
Heart 2 No  (2/2) N/A
Hippocampus 2 No  (2/2) N/A
Hypothalamus 2 No  (2/2) N/A
Kidney 2 No  (18/584)  (2/2) N/A
Large intestine 2 No  (10/584)  (2/2) N/A
Liver 2 No  (2/2) N/A
Lower urinary tract 2 No N/A
Lung 2 No  (2/2) N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Midbrain 2 No  (2/2) N/A
Olfactory lobe 2 No  (2/2) N/A
Ovary 2 No  (1/584) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/584)  (2/2) N/A
Peripheral nervous system 2 No  (2/2) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (2/2) N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (2/2) N/A
Small intestine 2 No  (9/584)  (2/2) N/A
Spinal cord 2 No  (2/2) N/A
Spleen 2 No  (2/584)  (2/2) N/A
Stomach 2 No  (12/584)  (2/2) N/A
Striatum 2 No  (2/2) N/A
Submandibular gland 2 No  (2/132)  (2/2) N/A
Testis 2 No  (2/584)  (1/2) N/A
Thalamus 2 No  (2/2) N/A
Thymus 2 No  (2/2) N/A
Thyroid gland 2 No  (15/584)  (2/2) N/A
Trachea 2 No  (2/2) N/A
Urinary bladder 2 No  (2/2) N/A
Uterus 2 No  (1/2) N/A
Vascular system 2 No  (2/2) N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/485)  (1/2) N/A
Dorsal root ganglion 1  (1/47) N/A
Ear 2  (1/485) N/A
Embryo 2  (1/485)  (2/2)  Wholemount images
Eye 2  (1/485)  (1/2) N/A
Foot 2  (1/485)  (1/2) N/A
Forebrain 2  (1/485) N/A
Forelimb 2  (1/485)  (1/2) N/A
Fronto-nasal process 1  (1/48) N/A
Hand 2  (1/485)  (1/2) N/A
Head 2  (5/485)  (2/2) N/A
Heart 2  (1/485)  (2/2) N/A
Hindbrain 2  (6/485)  (1/2) N/A
Hindlimb 2  (1/485)  (1/2) N/A
Liver 2  (1/485) N/A
Lung 2  (1/485) N/A
Mandibular process 2  (1/485) N/A
Maxillary process 2  (1/485) N/A
Midbrain 2  (1/485) N/A
Nose 1  (1/51) N/A
Oral cavity 2  (1/485) N/A
Skin 2  (1/485)  (2/2) N/A
Spinal cord 1  (1/50) N/A
Tail 2  (1/485)  (1/2) N/A
Tail somite 2  (1/485) N/A

 Associated Images

X-ray: XRay Images Lateral Orientation
10 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images
X-ray: XRay Images Forepaw
10 Images
Embryo LacZ: LacZ images wholemount
4 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
X-ray: XRay Images Dorso Ventral
10 Images

 Disease Models

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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Srd5a3tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Srd5a3tm43607(L1L2_st2) Targeting vectors
Srd5a3tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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