Gene Summary

Name:
kallikrein related-peptidase 11
Synonyms:
Prss20,  TLSP,  2310015I08Rik,  hippostasin

IMPC Data Collections

IMPC Phenotype Summary

Significant
Not Significant
Not tested

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

Phenotype System Allele Zyg Sex Life Stage P Value
abnormal thymus morphology Klk11em1(IMPC)Ccpcz HOM Early adult 0.00
abnormal skin morphology Klk11em1(IMPC)Ccpcz HOM Early adult 0.00
abnormal testis morphology Klk11em1(IMPC)Ccpcz HOM Early adult 0.00
abnormal liver morphology Klk11em1(IMPC)Ccpcz HOM Early adult 0.00
abnormal seminal vesicle morphology Klk11em1(IMPC)Ccpcz HOM Early adult 0.00
enlarged thymus Klk11em1(IMPC)Ccpcz HOM Early adult 0.00
abnormal joint morphology Klk11em1(IMPC)Ccpcz HOM   Early adult 9.96×10-06
abnormal cranium morphology Klk11em1(IMPC)Ccpcz HOM Early adult 7.89×10-05

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

X-ray

XRay Images Hind Leg and Hip

30 Images

X-ray

XRay Images Skull Lateral Orientation

15 Images

X-ray

XRay Images Whole Body Dorso Ventral

30 Images

X-ray

XRay Images Whole Body Lateral Orientation

15 Images

X-ray

XRay Images Forepaw

15 Images

X-ray

XRay Images Skull Dorso Ventral Orientation

15 Images

Human diseases caused by Klk11 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

No human diseases associated to this gene by orthology or annotation.

The table below shows human diseases predicted to be associated to Klk11 by phenotypic similarity.

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Klk11

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Klk11.

No publications found that use IMPC mice or data for Klk11.

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MGI Allele Allele Type Produced
Klk11tm1(KOMP)Mbp Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells
Klk11em1(IMPC)Ccpcz Exon Deletion Mice

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