Gene: Bcl11b

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Name
B cell leukemia/lymphoma 11B
MGI ID
MGI:1929913
Synonyms
COUP-TF interacting protein 2 CTIP2 B630002E05Rik Rit1 9130430L19Rik
Viability
Embryo viewer
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal eyelid fusion Bcl11btm1.1(KOMP)Vlcg HOM E18.5 0.00
abnormal bone structure Bcl11btm1.1(KOMP)Vlcg HET Early adult 1.58×10-11
preweaning lethality, complete penetrance Bcl11btm1.1(KOMP)Vlcg HOM   Early adult 0.00
abnormal facial morphology Bcl11btm1.1(KOMP)Vlcg HOM E18.5 0.00
increased fasting circulating glucose level Bcl11btm1.1(KOMP)Vlcg HET Early adult 2.89×10-06
increased lean body mass Bcl11btm1.1(KOMP)Vlcg HET Early adult 1.75×10-07
decreased total body fat amount Bcl11btm1.1(KOMP)Vlcg HET Early adult 1.89×10-11
increased bone mineral content Bcl11btm1.1(KOMP)Vlcg HET Early adult 8.92×10-09

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (4/583) N/A
Aorta 2 No  (1/583) N/A
Brain 2 No  (4/583) N/A
Brainstem 2 No  (2/583) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (1/583) N/A
Cerebellum 2 No  (3/583) N/A
Cerebral cortex 2 No  (2/583) N/A
Epididymis 2 No  (18/132) N/A
Esophagus 2 No  (7/407) N/A
Eye 2 No N/A
Heart 2 No  (2/583) N/A
Hippocampus 2 No  (3/583) N/A
Hypothalamus 2 No  (2/583) N/A
Kidney 2 No  (21/583) N/A
Large intestine 2 No  (10/583) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (1/583) N/A
Lung 2 No  (2/583) N/A
Lymph node 2 No  (1/583) N/A
Mammary gland 2 No N/A
Midbrain 2 No N/A
Olfactory lobe 2 No  (2/583) N/A
Ovary 2 No  (1/583) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/583) N/A
Peripheral nervous system 2 No  (2/583) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/583) N/A
Prostate gland 2 No  (12/583) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (1/583) N/A
Small intestine 2 No  (9/583) N/A
Spinal cord 2 No  (3/583) N/A
Spleen 2 No  (3/583) N/A
Stomach 2 No  (13/583) N/A
Striatum 2 No  (3/583) N/A
Submandibular gland 2 No  (2/130) N/A
Testis 2 No  (6/583) N/A
Thalamus 2 No N/A
Thymus 2 No  (1/583) N/A
Thyroid gland 2 No  (17/583) N/A
Trachea 2 No  (3/583) N/A
Urinary bladder 2 No N/A
Uterus 2 No N/A
Vascular system 2 No N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
2  (6/505) N/A
2  (1/60) N/A
2  (1/505) N/A
2  (1/506) N/A
2  (1/505) N/A
2  (1/505) N/A
2  (1/505) N/A
2  (1/505) N/A
2  (1/61) N/A
2  (1/505) N/A
2  (5/505) N/A
2  (1/505) N/A
2  (6/505) N/A
2  (1/505) N/A
2  (1/503) N/A
2  (1/503) N/A
2  (1/505) N/A
2  (1/505) N/A
2  (1/505) N/A
2  (1/75) N/A
2  (1/503) N/A
2  (1/505) N/A
2  (1/72) N/A
2  (1/505) N/A
2  (1/505) N/A

 Associated Images

X-ray: XRay Images Forepaw
9 Images
X-ray: XRay Images Whole Body Lateral Orientation
9 Images
X-ray: XRay Images Skull Lateral Orientation
9 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
9 Images
X-ray: XRay Images Whole Body Dorso Ventral
9 Images
Gross Morphology Embryo E18.5
8 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
6 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Bcl11btm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Bcl11btm1(KOMP)Mbp Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells
Bcl11btm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice

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