Smoc1 | SPARC related modular calcium binding 1
Physiological systems
22 / 24 physiological systems tested
14 Significantly impacted by the knock-out
Immune system Integument Growth/size/body region Hematopoietic system Cardiovascular system Craniofacial Homeostasis/metabolism Pigmentation Limbs/digits/tail Nervous system Vision/eye Behavior/neurological Skeleton Mortality/aging
8 No significant impact
2 Not tested
Gene metrics:27Significant phenotypes
2Associated diseases
Expression examined in:92Adult tissues
0Embryo tissues
short tibia | 1 supporting dataset | Smoc1tm1b(EUCOMM)Wtsi | homozygote | Early adult | 0 | ||
abnormal digit morphology | 5 supporting datasets | Smoc1tm1b(EUCOMM)Wtsi | homozygote | Early adult | 2.7x10-10 | ||
abnormal retina morphology | 1 supporting dataset | Smoc1tm1b(EUCOMM)Wtsi | homozygote | Early adult | 7.19x10-6 | ||
narrow eye opening | 1 supporting dataset | Smoc1tm1b(EUCOMM)Wtsi | homozygote | Early adult | 6.09x10-11 | ||
abnormal head size | 1 supporting dataset | Smoc1tm1b(EUCOMM)Wtsi | homozygote | Early adult | 3.87x10-8 | ||
abnormal optic disk morphology | 1 supporting dataset | Smoc1tm1b(EUCOMM)Wtsi | homozygote | Early adult | 3.28x10-10 | ||
abnormal pelvic girdle bone morphology | 1 supporting dataset | Smoc1tm1b(EUCOMM)Wtsi | homozygote | Early adult | 1.59x10-6 | ||
mydriasis | 1 supporting dataset | Smoc1tm1b(EUCOMM)Wtsi | homozygote | Early adult | 8.41x10-6 | ||
abnormal retina blood vessel morphology | 1 supporting dataset | Smoc1tm1b(EUCOMM)Wtsi | homozygote | Early adult | 8.48x10-7 | ||
increased basophil cell number | 2 supporting datasets | Smoc1tm1b(EUCOMM)Wtsi | heterozygote | Early adult | 1.14x10-6 |
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External links
No external links available for Smoc1.
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Smoc1tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
Smoc1tm1b(EUCOMM)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
Smoc1tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |