Genes Phenotypes

Gene: Smoc1

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Name
SPARC related modular calcium binding 1
MGI ID
MGI:1929878
Synonyms
2600002F22Rik SRG SPARC-related protein
Viability
Homozygous - Subviable
Embryo viewer
3D Imaging
Other links
MGI   Ensembl  
Significant phenotypes (11) Measurements chart (476) All data table (1193)
Expression & images (67) Disease models (0) Histopathology (2) Order (2)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
decreased erythrocyte cell number Smoc1tm1b(EUCOMM)Wtsi HET Early adult 7.75×10-05
megacephaly Smoc1tm1b(EUCOMM)Wtsi HOM Early adult 8.96×10-08
abnormal snout morphology Smoc1tm1b(EUCOMM)Wtsi HOM Early adult 8.97×10-10
abnormal behavior Smoc1tm1b(EUCOMM)Wtsi HET Early adult 2.00×10-06
mammalian phenotype Smoc1tm1a(EUCOMM)Wtsi HET Early adult 3.17×10-05
increased mean platelet volume Smoc1tm1b(EUCOMM)Wtsi HET Early adult 6.82×10-05
abnormal digit morphology Smoc1tm1b(EUCOMM)Wtsi HOM Early adult 3.74×10-10
abnormal coat/hair pigmentation Smoc1tm1a(EUCOMM)Wtsi HET Early adult 2.22×10-06
increased large unstained cell number Smoc1tm1b(EUCOMM)Wtsi HET Early adult 6.40×10-06
abnormal gait Smoc1tm1b(EUCOMM)Wtsi HOM Early adult 8.98×10-07
preweaning lethality, incomplete penetrance Smoc1tm1b(EUCOMM)Wtsi HOM Early adult 0.00

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 1 Yes  (2/584)  (2/2)  Wholemount images
Aorta 1 Yes  (2/2)  Wholemount images
Bone 1 No N/A
Brain 1 Yes  (2/2)  Wholemount images
Brainstem 1 No N/A
Brown adipose tissue 1 Yes  (2/2)  Wholemount images
Cartilage tissue 1 Yes  (2/2)  Wholemount images
Cerebellum 1 No N/A
Cerebral cortex 1 No N/A
Esophagus 1 No  (7/415) N/A
Eye 1 No N/A
Gall bladder 1 No  (2/2)  Wholemount images
Heart 1 No N/A
Hippocampus 1 No N/A
Hypothalamus 1 No N/A
Kidney 1 No  (18/584) N/A
Large intestine 1 No  (10/584)  (1/2)  Wholemount images
Liver 1 No N/A
Lower urinary tract 1 No  (2/2)  Wholemount images
Lung 1 No N/A
Lymph node 1 No N/A
Mammary gland 1 Yes  (1/2)  Wholemount images
Olfactory lobe 1 Yes  (2/2)  Wholemount images
Oral epithelium 1 No N/A
Ovary 1 No  (1/584) N/A
Oviduct 1 No N/A
Pancreas 1 No  (5/584)  (1/2)  Wholemount images
Parathyroid gland 1 No N/A
Peripheral nervous system 1 No N/A
Peyer's patch 1 No N/A
Pituitary gland 1 No N/A
Prostate gland 1 No  (12/584) N/A
Skeletal muscle 1 No N/A
Skin 1 No N/A
Small intestine 1 No  (9/584)  (2/2)  Wholemount images
Spinal cord 1 No N/A
Spleen 1 No  (2/584) N/A
Stomach 1 No  (12/584) N/A
Striatum 1 No N/A
Testis 1 No  (2/584)  (1/2)  Wholemount images
Thymus 1 No N/A
Thyroid gland 1 No  (15/584)  (1/2)  Wholemount images
Trachea 1 No N/A
Uterus 1 Yes  (1/2)  Wholemount images
Vascular system 1 Yes  (1/2)  Wholemount images
White adipose tissue 1 Yes  (2/2)  Wholemount images
LacZ Wholemount Images
adipose tissue (1)
White Adipose Tissue expression
Brown adipose tissue expression
MA:0000058
MA:0000057
cardiovascular system (2)
Aorta expression
MA:0000062
digestive system (3)
Gall Bladder expression
MA:0000356
endocrine system (2)
Adrenal gland expression
MA:0000116
exocrine system (1)
Mammary gland expression
MA:0000145
integumental system (1)
Mammary gland expression
MA:0000145
nervous system (2)
Olfactory Lobe expression
Brain expression
MA:0002413
MA:0000168
postnatal mouse (15)
Adrenal gland expression
MA:0000116
reproductive system (2)
Testis expression
MA:0000411
set of connective tissues (3)
Cartilage tissue expression
Vascular System expression
MA:0000104
MA:0002718
trunk (8)
Adrenal gland expression
MA:0000116
urinary system (1)
Lower Urinary Tract expression
MA:0002636
LacZ Section Images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/504)  (4/4) N/A
Ear 2  (1/504)  (1/4) N/A
Embryo 2  (1/505)  (4/4) N/A
Eye 2  (1/504)  (4/4) N/A
Foot 2  (1/504)  (3/4) N/A
Forebrain 2  (1/504)  (4/4) N/A
Forelimb 2  (1/504)  (3/4) N/A
Hand 2  (1/503)  (2/4) N/A
Head 2  (5/504)  (4/4) N/A
Heart 2  (1/504) N/A
Hindbrain 2  (6/504)  (4/4) N/A
Hindlimb 2  (1/503)  (3/4) N/A
Liver 2  (1/504) N/A
Lung 2  (1/500) N/A
Mandibular process 2  (1/504) N/A
Maxillary process 2  (1/504)  (2/4) N/A
Midbrain 2  (1/504)  (3/4) N/A
Oral cavity 2  (1/504)  (1/4) N/A
Skin 2  (1/504) N/A
Tail 2  (1/504)  (4/4) N/A
Tail somite 2  (1/504)  (4/4) N/A

 Associated Images

Embryo LacZ: LacZ images wholemount
8 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
7 Images
Echo: M-Mode Images
44 Images
Adult LacZ: LacZ Images Wholemount
15 Images

 Disease Models

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 Histopathology

Phenotype Allele Zygosity Sex Life Stage
Eye with optic nerve - inflammation Smoc1tm1b(EUCOMM)Wtsi HOM Early adult
Eye with optic nerve - atrophy Smoc1tm1b(EUCOMM)Wtsi HOM Early adult

 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Smoc1tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Smoc1tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells