Gene: Smoc1

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Name
SPARC related modular calcium binding 1
MGI ID
MGI:1929878
Synonyms
SRG SPARC-related protein 2600002F22Rik
Embryo viewer
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal behavior Smoc1tm1b(EUCOMM)Wtsi HET Early adult 1.32×10-05
increased thigmotaxis Smoc1tm1b(EUCOMM)Wtsi HET Early adult 1.32×10-05
decreased erythrocyte cell number Smoc1tm1b(EUCOMM)Wtsi HET   Early adult 6.20×10-05
increased mean platelet volume Smoc1tm1b(EUCOMM)Wtsi HET Early adult 1.69×10-05
increased red blood cell distribution width Smoc1tm1b(EUCOMM)Wtsi HOM   Early adult 3.92×10-10
increased anxiety-related response Smoc1tm1b(EUCOMM)Wtsi HET Early adult 2.25×10-05
short tibia Smoc1tm1b(EUCOMM)Wtsi HOM   Early adult 1.11×10-16
abnormal digit morphology Smoc1tm1b(EUCOMM)Wtsi HOM   Early adult 3.12×10-10
abnormal cranium morphology Smoc1tm1b(EUCOMM)Wtsi HOM Early adult 1.86×10-08
abnormal head size Smoc1tm1b(EUCOMM)Wtsi HOM Early adult 7.51×10-08
hypoactivity Smoc1tm1b(EUCOMM)Wtsi HET Early adult 2.31×10-05
abnormal maxilla morphology Smoc1tm1b(EUCOMM)Wtsi HOM Early adult 2.42×10-08
abnormal snout morphology Smoc1tm1b(EUCOMM)Wtsi HOM Early adult 9.70×10-10
decreased total body fat amount Smoc1tm1b(EUCOMM)Wtsi HOM   Early adult 2.69×10-08
abnormal pelvic girdle bone morphology Smoc1tm1b(EUCOMM)Wtsi HOM Early adult 1.65×10-06
preweaning lethality, incomplete penetrance Smoc1tm1b(EUCOMM)Wtsi HOM   Early adult 0.00
decreased circulating amylase level Smoc1tm1a(EUCOMM)Wtsi HET Early adult 9.86×10-09
abnormal coat/hair pigmentation Smoc1tm1a(EUCOMM)Wtsi HET Early adult 2.22×10-06
abnormal gait Smoc1tm1b(EUCOMM)Wtsi HOM Early adult 9.31×10-07
decreased circulating HDL cholesterol level Smoc1tm1b(EUCOMM)Wtsi HET   Early adult 1.20×10-05
abnormal maxilla morphology Smoc1tm1b(EUCOMM)Wtsi HET   Early adult 4.02×10-05
syndactyly Smoc1tm1b(EUCOMM)Wtsi HOM Early adult 3.81×10-09
hyperactivity Smoc1tm1b(EUCOMM)Wtsi HET   Early adult 5.59×10-05
decreased circulating iron level Smoc1tm1b(EUCOMM)Wtsi HET Early adult 6.65×10-05
decreased mean corpuscular hemoglobin Smoc1tm1b(EUCOMM)Wtsi HOM   Early adult 0.00

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 1 Yes  (3/590)  (2/2)  Wholemount images
Aorta 1 Yes  (1/590)  (2/2)  Wholemount images
Bone 1 No N/A
Brain 1 Yes  (3/590)  (2/2)  Wholemount images
Brainstem 1 No  (2/590) N/A
Brown adipose tissue 1 Yes  (2/2)  Wholemount images
Cartilage tissue 1 Yes  (2/2)  Wholemount images
Cerebellum 1 No  (3/590) N/A
Cerebral cortex 1 No  (2/590) N/A
Esophagus 1 No  (7/415) N/A
Eye 1 No N/A
Gall bladder 1 No  (2/2)  Wholemount images
Heart 1 No  (1/590) N/A
Hippocampus 1 No  (3/590) N/A
Hypothalamus 1 No  (2/590) N/A
Kidney 1 No  (20/590) N/A
Large intestine 1 No  (10/590)  (1/2)  Wholemount images
Liver 1 No N/A
Lower urinary tract 1 No  (1/590)  (2/2)  Wholemount images
Lung 1 No  (1/590) N/A
Lymph node 1 No N/A
Mammary gland 1 Yes  (1/2)  Wholemount images
Olfactory lobe 1 Yes  (2/590)  (2/2)  Wholemount images
Oral epithelium 1 No N/A
Ovary 1 No  (1/590) N/A
Oviduct 1 No N/A
Pancreas 1 No  (5/590)  (1/2)  Wholemount images
Parathyroid gland 1 No N/A
Peripheral nervous system 1 No  (1/590) N/A
Peyer's patch 1 No N/A
Pituitary gland 1 No  (1/590) N/A
Prostate gland 1 No  (12/590) N/A
Skeletal muscle 1 No N/A
Skin 1 No N/A
Small intestine 1 No  (9/590)  (2/2)  Wholemount images
Spinal cord 1 No  (2/590) N/A
Spleen 1 No  (2/590) N/A
Stomach 1 No  (13/590) N/A
Striatum 1 No  (3/590) N/A
Testis 1 No  (5/590)  (1/2)  Wholemount images
Thymus 1 No N/A
Thyroid gland 1 No  (16/590)  (1/2)  Wholemount images
Trachea 1 No  (2/590) N/A
Uterus 1 Yes  (1/2)  Wholemount images
Vascular system 1 Yes  (1/2)  Wholemount images
White adipose tissue 1 Yes  (2/2)  Wholemount images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/506)  (4/4) N/A
Ear 2  (1/506)  (1/4) N/A
Embryo 2  (1/507)  (4/4) N/A
Eye 2  (1/506)  (4/4) N/A
Foot 2  (1/506)  (3/4) N/A
Forebrain 2  (1/506)  (4/4) N/A
Forelimb 2  (1/506)  (3/4) N/A
Hand 2  (1/506)  (2/4) N/A
Head 2  (5/506)  (4/4) N/A
Heart 2  (1/506) N/A
Hindbrain 2  (6/506)  (4/4) N/A
Hindlimb 2  (1/506)  (3/4) N/A
Liver 2  (1/504) N/A
Lung 2  (1/504) N/A
Mandibular process 2  (1/506) N/A
Maxillary process 2  (1/506)  (2/4) N/A
Midbrain 2  (1/506)  (3/4) N/A
Oral cavity 2  (1/504)  (1/4) N/A
Skin 2  (1/506) N/A
Tail 2  (1/506)  (4/4) N/A
Tail somite 2  (1/506)  (4/4) N/A

 Associated Images

X-ray: XRay Images Whole Body Dorso Ventral
15 Images
Echo: M-Mode Images
44 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
16 Images
X-ray: XRay Images Whole Body Lateral Orientation
15 Images
Adult LacZ: LacZ Images Wholemount
15 Images
Embryo LacZ: LacZ images wholemount
8 Images
X-ray: XRay Images Hind Leg and Hip
2 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
7 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Smoc1tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Smoc1tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells