Genes Phenotypes

Gene: Smoc1

Name
SPARC related modular calcium binding 1
MGI ID
MGI:1929878
Synonyms
SPARC-related protein SRG 2600002F22Rik
Viability
Homozygous - Subviable
Other links
MGI   Ensembl  
Significant phenotypes (16) All measurements (1292) Expression & images (67) Disease models (0) Order (2)
View data by physiological system
Significant
Not Significant
Not tested
Body weight
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal pelvic girdle bone morphology Smoc1tm1b(EUCOMM)Wtsi HOM postnatal 9.96×10-07
syndactyly Smoc1tm1b(EUCOMM)Wtsi HOM postnatal 5.93×10-09
mammalian phenotype Smoc1tm1a(EUCOMM)Wtsi HET postnatal 3.17×10-05
increased mean platelet volume Smoc1tm1b(EUCOMM)Wtsi HET postnatal 7.01×10-05
abnormal snout morphology Smoc1tm1b(EUCOMM)Wtsi HOM postnatal 1.28×10-09
abnormal coat/hair pigmentation Smoc1tm1a(EUCOMM)Wtsi HET postnatal 2.22×10-06
abnormal cranium morphology Smoc1tm1b(EUCOMM)Wtsi HOM postnatal 2.89×10-08
increased large unstained cell number Smoc1tm1b(EUCOMM)Wtsi HET postnatal 6.33×10-06
abnormal head size Smoc1tm1b(EUCOMM)Wtsi HOM postnatal 7.28×10-08
decreased erythrocyte cell number Smoc1tm1b(EUCOMM)Wtsi HET postnatal 7.75×10-05
abnormal behavior Smoc1tm1b(EUCOMM)Wtsi HET postnatal 2.61×10-06
abnormal gait Smoc1tm1b(EUCOMM)Wtsi HOM postnatal 9.55×10-07
decreased body weight Smoc1tm1a(EUCOMM)Wtsi HET postnatal 1.06×10-06
abnormal digit morphology Smoc1tm1b(EUCOMM)Wtsi HOM postnatal 5.00×10-10
preweaning lethality, incomplete penetrance Smoc1tm1b(EUCOMM)Wtsi HOM n/a 0.00
abnormal maxilla morphology Smoc1tm1b(EUCOMM)Wtsi HOM postnatal 2.25×10-08

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Filtered by: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 1 Yes  (2/584)  (2/2)  Wholemount images
Aorta 1 Yes  (2/2)  Wholemount images
Bone 1 No N/A
Brain 1 Yes  (2/2)  Wholemount images
Brainstem 1 No N/A
Brown adipose tissue 1 Yes  (2/2)  Wholemount images
Cartilage tissue 1 Yes  (2/2)  Wholemount images
Cerebellum 1 No N/A
Cerebral cortex 1 No N/A
Esophagus 1 No  (7/415) N/A
Eye 1 No N/A
Gall bladder 1 No  (2/2)  Wholemount images
Heart 1 No N/A
Hippocampus 1 No N/A
Hypothalamus 1 No N/A
Kidney 1 No  (18/584) N/A
Large intestine 1 No  (10/584)  (1/2)  Wholemount images
Liver 1 No N/A
Lower urinary tract 1 No  (2/2)  Wholemount images
Lung 1 No N/A
Lymph node 1 No N/A
Mammary gland 1 Yes  (1/2)  Wholemount images
Olfactory lobe 1 Yes  (2/2)  Wholemount images
Oral epithelium 1 No N/A
Ovary 1 No  (1/584) N/A
Oviduct 1 No N/A
Pancreas 1 No  (5/584)  (1/2)  Wholemount images
Parathyroid gland 1 No N/A
Peripheral nervous system 1 No N/A
Peyer's patch 1 No N/A
Pituitary gland 1 No N/A
Prostate gland 1 No  (12/584) N/A
Skeletal muscle 1 No N/A
Skin 1 No N/A
Small intestine 1 No  (9/584)  (2/2)  Wholemount images
Spinal cord 1 No N/A
Spleen 1 No  (2/584) N/A
Stomach 1 No  (12/584) N/A
Striatum 1 No N/A
Testis 1 No  (2/584)  (1/2)  Wholemount images
Thymus 1 No N/A
Thyroid gland 1 No  (15/584)  (1/2)  Wholemount images
Trachea 1 No N/A
Uterus 1 Yes  (1/2)  Wholemount images
Vascular system 1 Yes  (1/2)  Wholemount images
White adipose tissue 1 Yes  (2/2)  Wholemount images
LacZ Wholemount Images
adipose tissue (1)
White Adipose Tissue expression
Brown adipose tissue expression
MA:0000058
MA:0000057
cardiovascular system (2)
Aorta expression
MA:0000062
digestive system (3)
Gall Bladder expression
MA:0000356
endocrine system (2)
Adrenal gland expression
MA:0000116
exocrine system (1)
Mammary gland expression
MA:0000145
integumental system (1)
Mammary gland expression
MA:0000145
nervous system (2)
Olfactory Lobe expression
Brain expression
MA:0002413
MA:0000168
postnatal mouse (15)
Adrenal gland expression
MA:0000116
reproductive system (2)
Testis expression
MA:0000411
set of connective tissues (3)
Cartilage tissue expression
Vascular System expression
MA:0000104
MA:0002718
trunk (8)
Adrenal gland expression
MA:0000116
urinary system (1)
Lower Urinary Tract expression
MA:0002636
LacZ Section Images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/485)  (4/4) N/A
Ear 2  (1/485)  (1/4) N/A
Embryo 2  (1/485)  (4/4) N/A
Eye 2  (1/485)  (4/4) N/A
Foot 2  (1/485)  (3/4) N/A
Forebrain 2  (1/485)  (4/4) N/A
Forelimb 2  (1/485)  (3/4) N/A
Hand 2  (1/485)  (2/4) N/A
Head 2  (5/485)  (4/4) N/A
Heart 2  (1/485) N/A
Hindbrain 2  (6/485)  (4/4) N/A
Hindlimb 2  (1/485)  (3/4) N/A
Liver 2  (1/485) N/A
Lung 2  (1/485) N/A
Mandibular process 2  (1/485) N/A
Maxillary process 2  (1/485)  (2/4) N/A
Midbrain 2  (1/485)  (3/4) N/A
Oral cavity 2  (1/485)  (1/4) N/A
Skin 2  (1/485) N/A
Tail 2  (1/485)  (4/4) N/A
Tail somite 2  (1/485)  (4/4) N/A

 Associated Images

X-ray: XRay Images Dorso Ventral
15 Images
X-ray: XRay Images Lateral Orientation
15 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
16 Images
Adult LacZ: LacZ Images Wholemount
15 Images
X-ray: XRay Images Hind Leg and Hip
2 Images
Echo: M-Mode Images
44 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
7 Images

 Disease Models

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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Smoc1tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Smoc1tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells