Gene: Hacl1

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Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
impaired glucose tolerance Hacl1tm1a(KOMP)Wtsi HOM Early adult 3.47×10-07
enlarged heart Hacl1tm1b(KOMP)Wtsi HOM Early adult 0.00
abnormal heart morphology Hacl1tm1b(KOMP)Wtsi HOM Early adult 0.00
abnormal eye morphology Hacl1tm1b(KOMP)Wtsi HOM Early adult 0.00
decreased circulating magnesium level Hacl1tm1a(KOMP)Wtsi HOM Early adult 5.11×10-05

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (4/583)  (2/2)  Section images
Aorta 2 No  (1/583)  (1/2)  Section images
Blood 2 No N/A
Bone marrow 2 No N/A
Brain 2 No  (4/583) N/A
Brainstem 2 No  (2/583) N/A
Brown adipose tissue 2 No  (1/2)  Section images
Cartilage tissue 2 No  (1/583) N/A
Cecum 2 No  (12/371)  (1/2)  Section images
Cerebellum 2 No  (3/583)  (2/2)  Section images
Cerebral cortex 2 No  (2/583) N/A
Chest bone 2 No N/A
Colon 2 No  (12/127)  (2/2)  Section images
Diaphragm 2 No N/A
Duodenum 2 No  (2/127)  (1/2)  Section images
Epididymis 2 No  (18/132)  (1/2)  Section images
Esophagus 2 No  (7/407)  (1/2)  Section images
Eye 2 No  (1/2)  Section images
Gall bladder 2 No N/A
Gonadal fat pad 2 No  (1/2)  Section images
Harderian gland 2 No  (2/2)  Section images
Heart 2 No  (2/583) N/A
Hindlimb 2 No N/A
Hippocampus 2 No  (3/583) N/A
Hypothalamus 2 No  (2/583) N/A
Ileum 2 No  (14/127)  (2/2)  Section images
Jejunum 2 No  (6/127) N/A
Kidney 2 No  (21/583)  (2/2)  Section images
Large intestine 2 No  (10/583) N/A
Liver 2 No  (2/2)  Section images
Lower urinary tract 2 No  (1/583) N/A
Lung 2 No  (2/583)  (1/2)  Section images
Lymph node 2 No  (1/583) N/A
Mammary gland 2 No N/A
Mesenteric adipose tissue 2 No  (1/2)  Section images
Mesenteric lymph node 2 No N/A
Midbrain 2 No  (2/2)  Section images
Olfactory lobe 2 No  (2/583)  (1/2)  Section images
Ovary 2 No  (1/583) N/A
Oviduct 2 No  (1/2)  Section images
Pancreas 2 No  (5/583) N/A
Parathyroid gland 2 No  (1/563)  (2/2)  Section images
Parotid gland 2 No N/A
Penis 2 No  (1/2)  Section images
Peripheral nervous system 2 No  (2/583) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/583) N/A
Prostate gland 2 No  (12/583)  (1/2)  Section images
Quadriceps 2 No  (1/2)  Section images
Sciatic nerve 2 No  (1/2)  Section images
Skeletal muscle 2 No N/A
Skin 2 No  (1/583)  (1/2)  Section images
Small intestine 2 No  (9/583) N/A
Spinal cord 2 No  (3/583)  (2/2)  Section images
Spleen 2 No  (3/583)  (1/2)  Section images
Stomach 2 No  (13/583)  (2/2)  Section images
Stomach pyloric region 2 No N/A
Striatum 2 No  (3/583) N/A
Sublingual gland 2 No  (1/2)  Section images
Submandibular gland 2 No  (2/130)  (1/2)  Section images
Testis 2 No  (6/583)  (1/2)  Section images
Thymus 2 No  (1/583) N/A
Thyroid gland 2 No  (17/583) N/A
Tongue 2 No  (5/127)  (1/2)  Section images
Trachea 2 No  (3/583)  (1/2)  Section images
Trigeminal V nerve 2 No  (1/2)  Section images
Urinary bladder 2 No  (2/2)  Section images
Uterus 2 No N/A
Vagina 2 No N/A
Vas deferens 2 No  (15/382)  (1/2)  Section images
Vascular system 2 No N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No N/A
No Embryo expression data was found for this gene.

 Associated Images

Adult LacZ: LacZ Images Section
85 Images
X-ray: XRay Images Whole Body Dorso Ventral
24 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
24 Images
X-ray: XRay Images Forepaw
23 Images
X-ray: XRay Images Whole Body Lateral Orientation
22 Images
X-ray: XRay Images Skull Lateral Orientation
22 Images
X-ray: XRay Images Hind Leg and Hip
10 Images
Legacy Phenotype Associated Images

View all 65 images

View all 6 images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Histopathology

 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Hacl1tm43010(L1L2_gt0) Targeting vectors
Hacl1tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Hacl1tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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