Gene: Scamp5

Name secretory carrier membrane protein 5

Synonyms Sc5

Status ES CellsMice
tm1
Mice
tm1.1
phenotype data available

Links MGI:1928948   Ensembl Gene   Ensembl Orthologs

Viability Homozygous - Lethal

Phenotype associations for Scamp5

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Scamp5 data for that phenotype.

Embryo Data: 3D Embryo Imaging
Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
preweaning lethality, complete penetrance Scamp5tm1.1(KOMP)Vlcg HOM Female Male n/a 0.0
hyperactivity Scamp5tm1.1(KOMP)Vlcg HET Female Male postnatal 5.47E-17
abnormal behavior Scamp5tm1.1(KOMP)Vlcg HET Female Male postnatal 2.77E-10
abnormal sleep behavior Scamp5tm1.1(KOMP)Vlcg HET Female Male postnatal 5.7E-9
decreased total body fat amount Scamp5tm1.1(KOMP)Vlcg HET Female Male postnatal 2.61E-8
increased bone mineral content Scamp5tm1.1(KOMP)Vlcg HET Female Male postnatal 9.63E-7
abnormal behavioral response to light Scamp5tm1.1(KOMP)Vlcg HET Female Male postnatal 1.23E-5
increased lean body mass Scamp5tm1.1(KOMP)Vlcg HET Female Male postnatal 2.55E-5
decreased body length Scamp5tm1.1(KOMP)Vlcg HET Female Male postnatal 4.71E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (5/393) (2/2)
Aorta 2 No (1/562) (2/2)
Bone marrow 2 No (2/2)
Brain 2 No (6/562) (2/2)
Brainstem 2 No (4/562) (2/2)
Brown adipose tissue 2 No (2/2)
Cartilage tissue 2 No (1/562) (2/2)
Cerebellum 2 No (4/562) (2/2)
Cerebral cortex 2 No (5/562) (2/2)
Epididymis 2 No (4/106) (1/2)
Esophagus 2 No (2/393) (2/2)
Eye 2 No (1/562) (2/2)
Heart 2 No (3/562) (2/2)
Hippocampus 2 No (5/562) (2/2)
Hypothalamus 2 No (4/562) (2/2)
Kidney 2 No (20/562) (2/2)
Large intestine 2 No (12/562) (2/2)
Liver 2 No (2/2)
Lower urinary tract 2 No (3/562)
Lung 2 No (3/562) (2/2)
Lymph node 2 No (1/562) (2/2)
Mammary gland 2 No
Midbrain 2 No (2/2)
Olfactory lobe 2 No (4/393) (2/2)
Ovary 2 No (1/562) (1/2)
Oviduct 2 No (2/562) (1/2)
Pancreas 2 No (6/562) (2/2)
Peripheral nervous system 2 No (3/562) (2/2)
Peyer's patch 2 No (1/393) (2/2)
Pituitary gland 2 No (1/562) (2/2)
Prostate gland 2 No (5/562)
Skeletal muscle 2 No
Skin 2 No (1/562) (2/2)
Small intestine 2 No (11/562) (2/2)
Spinal cord 2 No (3/562) (2/2)
Spleen 2 No (4/562) (2/2)
Stomach 2 No (9/562) (2/2)
Striatum 2 No (4/562) (2/2)
Submandibular gland 2 No (1/104)
Testis 2 No (4/562) (1/2)
Thalamus 2 No (2/2)
Thymus 2 No (2/2)
Thyroid gland 2 No (16/562)
Trachea 2 No (3/562) (2/2)
Urinary bladder 2 No (2/2)
Uterus 2 No (2/562) (1/2)
Vascular system 2 No (1/393) (2/2)
Vesicular gland 2 No
White adipose tissue 2 No (2/2)
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system
    respiratory system
    digestive system
    cardiovascular system
    set of connective tissues
    reproductive system
    adipose tissue
    musculoskeletal system
    trunk
    postnatal mouse
    nervous system
    sensory organ
    immune system
    integumental system
    urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2 (6/440) (2/3)
Dorsal root ganglion 2 (1/3) (2/3)
Ear 2 (1/440) (2/3)
Embryo 2 (1/440) (2/3)
Eye 2 (1/440) (2/3)
Foot 2 (2/3)
Forebrain 2 (1/440) (2/3)
Forelimb 2 (1/440) (2/3)
Fronto-nasal process 2 (1/4) Image Only
Hand 2 (2/3)
Head 2 (5/440) (2/3)
Heart 2 (1/440) Image Only
Hindbrain 2 (5/440) (2/3)
Hindlimb 2 (1/440) (2/3)
Liver 2 (1/440) (2/3)
Lung 2 (1/440) Image Only
Mandibular process 2 (1/440) (2/3)
Maxillary process 2 (1/440) (2/3)
Midbrain 2 (1/440) (2/3)
Nose 2 (1/5) (2/3)
Oral cavity 2 (1/440) Image Only
Skin 2 (1/440) (2/3)
Spinal cord 2 (1/4) (2/3)
Tail 2 (1/440) (2/3)
Tail somite 2 (1/440) Image Only


Associated Images

Associated Images
  • Electroretinography 2: Rod and cone PDF
    3 Images
  • Embryo LacZ: LacZ images wholemount
    12 Images
  • Gross Morphology Embryo E12.5
    2 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Scamp5tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene
Scamp5tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette)
Vector
Gene
Scamp5tm374539(L1L2_Bact_P)
Vector
Gene