Gene: Svep1

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Name
sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
MGI ID
MGI:1928849
Synonyms
4833413O10Rik D430029O09Rik 1110021D17Rik Polydom
Viability
Embryo viewer
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
decreased circulating phosphate level Svep1tm1b(EUCOMM)Hmgu HET Early adult 4.64×10-06
increased hemoglobin content Svep1tm1b(EUCOMM)Hmgu HET   Early adult 1.52×10-05
narrow eye opening Svep1tm1b(EUCOMM)Hmgu HET Late adult 9.31×10-05
preweaning lethality, complete penetrance Svep1tm1b(EUCOMM)Hmgu HOM   Early adult 0.00
improved glucose tolerance Svep1tm1b(EUCOMM)Hmgu HET Early adult 6.14×10-05
edema Svep1tm1b(EUCOMM)Hmgu HOM E15.5 0.00
edema Svep1tm1b(EUCOMM)Hmgu HOM E18.5 0.00
exophthalmos Svep1tm1b(EUCOMM)Hmgu HET Late adult 9.31×10-05
abnormal iris pigmentation Svep1tm1b(EUCOMM)Hmgu HET Late adult 4.68×10-05
corneal deposits Svep1tm1b(EUCOMM)Hmgu HET Late adult 6.01×10-05
impaired pupillary reflex Svep1tm1b(EUCOMM)Hmgu HET Late adult 4.68×10-05
abnormal eyelid morphology Svep1tm1b(EUCOMM)Hmgu HET Late adult 6.01×10-05
increased hematocrit Svep1tm1b(EUCOMM)Hmgu HET Early adult 9.08×10-05
abnormal limb morphology Svep1tm1b(EUCOMM)Hmgu HOM E18.5 0.00
increased erythrocyte cell number Svep1tm1b(EUCOMM)Hmgu HET   Early adult 6.70×10-05
abnormal tail morphology Svep1tm1b(EUCOMM)Hmgu HOM E18.5 0.00
abnormal iris transillumination Svep1tm1b(EUCOMM)Hmgu HET Late adult 4.68×10-05
abnormal skin appearance Svep1tm1b(EUCOMM)Hmgu HOM E18.5 0.00
eyelids fail to open Svep1tm1b(EUCOMM)Hmgu HET Late adult 6.01×10-05

Download data as:  TSV  XLS

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
2 No  (4/583) N/A
2 No  (1/583) N/A
2 No  (4/583) N/A
2 No  (2/583) N/A
2 No N/A
2 No  (1/583) N/A
2 No  (3/583) N/A
2 No  (2/583) N/A
2 No  (18/132) N/A
2 No  (7/407) N/A
2 No N/A
2 No  (2/583) N/A
2 No  (3/583) N/A
2 No  (2/583) N/A
2 No  (21/583)  (2/2)  Section images
2 No  (10/583) N/A
2 No N/A
2 No  (1/583) N/A
2 No  (2/583)  (2/2)  Section images
2 No  (1/583) N/A
2 No N/A
2 No N/A
2 No  (2/583) N/A
2 No  (1/583) N/A
2 No N/A
2 No  (5/583)  (2/2)  Section images
2 No  (2/583) N/A
2 No N/A
2 No  (1/583) N/A
2 No  (12/583) N/A
2 No N/A
2 No  (1/583)  (2/2)  Section images
2 No  (9/583)  (2/2)  Section images
2 No  (3/583) N/A
2 No  (3/583)  (2/2)  Section images
2 No  (13/583)  (2/2)  Section images
2 No  (3/583) N/A
2 No  (2/130) N/A
2 No  (6/583)  (1/2)  Section images
2 No N/A
2 No  (1/583) N/A
2 No  (17/583) N/A
2 No  (3/583) N/A
2 No N/A
2 No  (1/2)  Section images
2 No N/A
2 No N/A
2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
2  (6/505)  (1/2) N/A
1  (1/60) N/A
2  (1/505) N/A
2  (1/506)  (1/2)  Wholemount images
2  (1/505) N/A
2  (1/505)  (1/2) N/A
2  (1/505)  (1/2) N/A
2  (1/505)  (1/2) N/A
1  (1/61) N/A
2  (1/505)  (1/2) N/A
2  (5/505)  (1/2) N/A
2  (1/505)  (1/2) N/A
2  (6/505)  (1/2) N/A
2  (1/505)  (1/2) N/A
2  (1/503) N/A
2  (1/503)  (1/2) N/A
2  (1/505)  (1/2) N/A
2  (1/505)  (1/2) N/A
2  (1/505)  (1/2) N/A
1  (1/75) N/A
2  (1/503) N/A
2  (1/505)  (1/2) N/A
1  (1/72) N/A
2  (1/505)  (1/2) N/A
2  (1/505) N/A

 Associated Images

X-ray: XRay Images Whole Body Dorso Ventral
10 Images
X-ray: XRay Images Forepaw
10 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
Eye Morphology: Images Slit Lamp
1 Images
Electrocardiogram (ECG): Waveform Image
16 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images
Original Image
Adult LacZ: LacZ Images Section
9 Images
Embryo LacZ: LacZ images wholemount
4 Images
Electroretinography 2: Rod and cone PDF
4 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Svep1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Svep1tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice

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