Gene: Svep1

Name
sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
MGI ID
MGI:1928849
Synonyms
4833413O10Rik D430029O09Rik Polydom 1110021D17Rik
Viability
Homozygous - Lethal
Other links
View data by physiological system
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal skin appearance Svep1tm1b(EUCOMM)Hmgu HOM embryonic day 18.5 0.00
abnormal limb morphology Svep1tm1b(EUCOMM)Hmgu HOM embryonic day 18.5 0.00
decreased total body fat amount Svep1tm1b(EUCOMM)Hmgu HET postnatal 1.51×10-06
preweaning lethality, complete penetrance Svep1tm1b(EUCOMM)Hmgu HOM n/a 0.00
decreased circulating phosphate level Svep1tm1b(EUCOMM)Hmgu HET postnatal 5.97×10-06
increased hematocrit Svep1tm1b(EUCOMM)Hmgu HET postnatal 2.58×10-05
embryonic lethality prior to tooth bud stage Svep1tm1b(EUCOMM)Hmgu HOM embryonic day 12.5 0.00
abnormal tail morphology Svep1tm1b(EUCOMM)Hmgu HOM embryonic day 18.5 0.00
edema Svep1tm1b(EUCOMM)Hmgu HOM embryonic day 18.5 0.00
edema Svep1tm1b(EUCOMM)Hmgu HOM embryonic day 15.5 0.00

Download data as:  TSV  XLS

Filtered by: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Brain 2 No N/A
Brainstem 2 No N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Epididymis 2 No  (18/134) N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Heart 2 No N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Kidney 2 No  (18/584)  (2/2) N/A
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No  (2/2) N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Midbrain 2 No N/A
Olfactory lobe 2 No N/A
Ovary 2 No  (1/584) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/584)  (2/2) N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (2/2) N/A
Small intestine 2 No  (9/584)  (2/2) N/A
Spinal cord 2 No N/A
Spleen 2 No  (2/584)  (2/2) N/A
Stomach 2 No  (12/584)  (2/2) N/A
Striatum 2 No N/A
Submandibular gland 2 No  (2/132) N/A
Testis 2 No  (2/584)  (1/2) N/A
Thalamus 2 No N/A
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No N/A
Urinary bladder 2 No N/A
Uterus 2 No  (1/2) N/A
Vascular system 2 No N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/485)  (1/2) N/A
Dorsal root ganglion 1  (1/47) N/A
Ear 2  (1/485) N/A
Embryo 2  (1/485)  (1/2)  Wholemount images
Eye 2  (1/485) N/A
Foot 2  (1/485)  (1/2) N/A
Forebrain 2  (1/485)  (1/2) N/A
Forelimb 2  (1/485)  (1/2) N/A
Fronto-nasal process 1  (1/48) N/A
Hand 2  (1/485)  (1/2) N/A
Head 2  (5/485)  (1/2) N/A
Heart 2  (1/485)  (1/2) N/A
Hindbrain 2  (6/485)  (1/2) N/A
Hindlimb 2  (1/485)  (1/2) N/A
Liver 2  (1/485) N/A
Lung 2  (1/485)  (1/2) N/A
Mandibular process 2  (1/485)  (1/2) N/A
Maxillary process 2  (1/485)  (1/2) N/A
Midbrain 2  (1/485)  (1/2) N/A
Nose 1  (1/51) N/A
Oral cavity 2  (1/485) N/A
Skin 2  (1/485)  (1/2) N/A
Spinal cord 1  (1/50) N/A
Tail 2  (1/485)  (1/2) N/A
Tail somite 2  (1/485) N/A

 Associated Images

X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images
Gross Morphology Embryo E18.5
4 Images
X-ray: XRay Images Lateral Orientation
10 Images
X-ray: XRay Images Dorso Ventral
10 Images
Gross Morphology Embryo E14.5-E15.5
4 Images
Embryo LacZ: LacZ images wholemount
4 Images
X-ray: XRay Images Forepaw
10 Images
Electroretinography 2: Rod and cone PDF
4 Images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Svep1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Svep1tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice

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