Gene: Tdo2

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Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal embryo size Tdo2tm1b(KOMP)Mbp HOM E15.5 0.00
enlarged heart Tdo2tm1b(KOMP)Mbp HET Early adult 0.00
preweaning lethality, incomplete penetrance Tdo2tm1b(KOMP)Mbp HOM   Early adult 0.00
abnormal embryo size Tdo2tm1b(KOMP)Mbp HET E15.5 0.00
small superior vagus ganglion Tdo2tm1b(KOMP)Mbp HET Early adult 0.00
abnormal craniofacial morphology Tdo2tm1b(KOMP)Mbp HOM E15.5 0.00
increased prepulse inhibition Tdo2tm1b(KOMP)Mbp HET   Early adult 5.20×10-07
abnormal heart morphology Tdo2tm1b(KOMP)Mbp HET Early adult 0.00
hydrometra Tdo2tm1b(KOMP)Mbp HET Early adult 0.00
abnormal craniofacial morphology Tdo2tm1b(KOMP)Mbp HET E15.5 0.00

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (3/590) N/A
Aorta 2 No  (1/590) N/A
Blood 2 No N/A
Bone marrow 2 No N/A
Brain 2 No  (3/590) N/A
Brainstem 2 No  (2/590) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cecum 2 No  (12/377) N/A
Cerebellum 2 No  (3/590)  (2/2)  Section images
Cerebral cortex 2 No  (2/590) N/A
Chest bone 2 No N/A
Colon 2 No  (12/127) N/A
Diaphragm 2 No N/A
Duodenum 2 No  (2/127)  (2/2)  Section images
Epididymis 2 No  (18/134)  (1/2)  Section images
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Gonadal fat pad 2 No N/A
Harderian gland 2 No N/A
Heart 2 No  (1/590) N/A
Hindlimb 2 No N/A
Hippocampus 2 No  (3/590) N/A
Hypothalamus 2 No  (2/590) N/A
Ileum 2 No  (14/127)  (2/2)  Section images
Jejunum 2 No  (6/127)  (1/2)  Section images
Kidney 2 No  (20/590) N/A
Large intestine 2 No  (10/590) N/A
Liver 2 No  (1/2)  Section images
Lower urinary tract 2 No  (1/590) N/A
Lung 2 No  (1/590) N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Mesenteric adipose tissue 2 No N/A
Mesenteric lymph node 2 No N/A
Midbrain 2 No N/A
Olfactory lobe 2 No  (2/590) N/A
Ovary 2 No  (1/590) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/590) N/A
Parathyroid gland 2 No N/A
Parotid gland 2 No N/A
Penis 2 No  (1/2)  Section images
Peripheral nervous system 2 No  (1/590) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/590) N/A
Prostate gland 2 No  (12/590)  (1/2)  Section images
Quadriceps 2 No N/A
Sciatic nerve 2 No N/A
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/590) N/A
Spinal cord 2 No  (2/590) N/A
Spleen 2 No  (2/590) N/A
Stomach 2 No  (13/590) N/A
Stomach pyloric region 2 No N/A
Striatum 2 No  (3/590) N/A
Sublingual gland 2 No N/A
Submandibular gland 2 No  (2/132) N/A
Testis 2 No  (5/590)  (1/2)  Section images
Thymus 2 No N/A
Thyroid gland 2 No  (16/590) N/A
Tongue 2 No  (5/127) N/A
Trachea 2 No  (2/590) N/A
Trigeminal V nerve 2 No N/A
Urinary bladder 2 No N/A
Uterus 2 No N/A
Vagina 2 No N/A
Vas deferens 2 No  (15/388)  (1/2)  Section images
Vascular system 2 No N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No N/A
No Embryo expression data was found for this gene.

 Associated Images

X-ray: XRay Images Whole Body Lateral Orientation
10 Images
Adult LacZ: LacZ Images Section
24 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images
Gross Morphology Embryo E14.5-E15.5
20 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Tdo2tm1b(KOMP)Mbp Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Tdo2tm1a(KOMP)Mbp KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Tdo2tm2a(KOMP)Mbp KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Tdo2tm41820(L1L2_gt0) Targeting vectors

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