Not currently registered for phenotyping at IMPC

Phenotyping is currently not planned for a knockout strain of this gene.

Gene Summary

Name:
acid phosphatase, prostate
Synonyms:
PAP,  A030005E02Rik

IMPC Data Collections

  • No Body Weight Data
  • No Embryo Imaging Data
  • No Viability Data

IMPC Phenotype Summary

Significant
Not Significant
Not tested

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Phenotype associated images not available

Human diseases caused by Acpp mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

No human diseases associated to this gene by orthology or annotation.

The table below shows human diseases predicted to be associated to Acpp by phenotypic similarity.

Disease Similarity of
phenotypes
Matching phenotypes Source
Trigeminal Neuralgia
Mandibular pain, Ocular pain, Neoplasm, Allodynia, Trigeminal neuralgia ORPHA:221091
Benign Schwannoma
Schwannoma, Peripheral Schwannoma, Scleral schwannoma, Pain, Allodynia, Abnormal parotid gland mo... ORPHA:252164
Complex Regional Pain Syndrome
Limb pain, Allodynia ORPHA:83452
Anterior Cutaneous Nerve Entrapment Syndrome
Back pain, Abdominal pain, Allodynia ORPHA:51890
Hereditary Breast And Ovarian Cancer Syndrome
Primary peritoneal carcinoma, Melanoma, Breast carcinoma, Ovarian neoplasm, Prostate cancer, Abno... ORPHA:145
Ovarian Cancer
Breast carcinoma, Dysgerminoma, Ovarian papillary adenocarcinoma OMIM:167000
Breast-Ovarian Cancer, Familial, Susceptibility To, 2
Breast carcinoma, Ovarian neoplasm OMIM:612555
Breast-Ovarian Cancer, Familial, Susceptibility To, 1
Breast carcinoma, Ovarian neoplasm OMIM:604370
Breast-Ovarian Cancer, Familial, Susceptibility To, 3
Breast carcinoma, Ovarian carcinoma OMIM:613399
Serrated Polyposis Syndrome
Bladder carcinoma, Colorectal polyposis, Schwannoma, Melanoma, Breast carcinoma, Biliary tract ne... ORPHA:157798
Neurotrophic Keratopathy
Allodynia ORPHA:137596
46,Xy Sex Reversal 10
Micropenis, Gonadoblastoma, Sex reversal, Ambiguous genitalia, Dysgerminoma, Decreased testicular... OMIM:616425
Gonadoblastoma
Abnormality of the ovary, Ovarian gonadoblastoma, Abdominal pain, Gonadal calcification, Ambiguou... ORPHA:206484
Li-Fraumeni Syndrome
Central primitive neuroectodermal tumor, Neoplasm of the gastrointestinal tract, Colon cancer, Ly... ORPHA:524
Cowden-Like syndrome
Uterine leiomyoma, Breast carcinoma, Papillary thyroid carcinoma, Endometrial carcinoma OMIM:612359
Familial Multinodular Goiter
Colorectal polyposis, Medulloepithelioma, Sertoli cell neoplasm, Testicular seminoma, Ovarian neo... ORPHA:276399
Muir-Torre Syndrome
Malignant genitourinary tract tumor, Renal neoplasm, Adenoma sebaceum, Colon cancer, Breast carci... ORPHA:587
Nthl1-Related Attenuated Familial Adenomatous Polyposis
Non-Hodgkin lymphoma, Squamous cell carcinoma, Colon cancer, Breast carcinoma, Neoplasm of the re... ORPHA:454840
Colorectal Cancer, Hereditary Nonpolyposis, Type 4
Endometrial carcinoma, Hereditary nonpolyposis colorectal carcinoma, Ovarian neoplasm OMIM:614337
Colorectal Cancer, Susceptibility To, 10
Colorectal polyposis, Carcinoma, Endometrial carcinoma OMIM:612591
Polymerase Proofreading-Related Adenomatous Polyposis
Colorectal polyposis, Breast carcinoma, Brain neoplasm, Adenocarcinoma of the colon, Neoplasm of ... ORPHA:447877
Endometrial Cancer
Endometrial carcinoma OMIM:608089

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Acpp

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Acpp.

No publications found that use IMPC mice or data for Acpp.

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MGI Allele Allele Type Produced
Acpptm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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