Not currently registered for phenotyping at IMPC

Phenotyping is currently not planned for a knockout strain of this gene.

Gene Summary

programmed cell death 10
Tfa15,  CCM3,  TF-1 cell apoptosis related protein-15,  2410003B13Rik

IMPC Data Collections

  • No Body Weight Data
  • No Embryo Imaging Data
  • No Viability Data

IMPC Phenotype Summary

Not Significant
Not tested


The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Legacy Phenotype Associated Images

View all 32 images

Human diseases caused by Pdcd10 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

The table below shows human diseases associated to Pdcd10 by orthology or direct annotation.

Disease Similarity of
Matching phenotypes Source
Familial Cerebral Cavernous Malformation
Cerebral Cavernous Malformations 3

The table below shows human diseases predicted to be associated to Pdcd10 by phenotypic similarity.

Disease Similarity of
Matching phenotypes Source
Hemoglobin D Disease
Reduced beta/alpha synthesis ratio, Decreased mean corpuscular hemoglobin concentration, Abnormal... ORPHA:90039
Hereditary Persistence Of Fetal Hemoglobin-Beta-Thalassemia Syndrome
Pallor, Anemia, Splenomegaly, Persistence of hemoglobin F ORPHA:46532
Diamond-Blackfan Anemia 19
Anemia, Erythroid hypoplasia, Steroid-responsive anemia OMIM:618312
Transient Erythroblastopenia Of Childhood
Transient erythroblastopenia, Anemia OMIM:227050
Anemia, Hypochromic Microcytic, With Iron Overload 2
Poikilocytosis, Splenomegaly, Anemia, Pallor, Decreased mean corpuscular volume, Hypochromia OMIM:615234
Autoimmune Hemolytic Anemia, Cold Type
Pallor, Splenomegaly, Abnormal leukocyte morphology, Hemolytic anemia ORPHA:228312
Anemia, Congenital Dyserythropoietic, Type Ib
Reticulocytosis, Splenomegaly, Anisocytosis, Anemia, Erythroid hyperplasia, Pallor, Anemia of ina... OMIM:615631
Acute Myelomonocytic Leukemia
Eosinophilia, Leukocytosis, Anemia, Pallor, Thrombocytopenia ORPHA:517
Muscular Dystrophy, Limb-Girdle, Autosomal Dominant 2
Flexion contracture, Muscular dystrophy, EMG: myopathic abnormalities, Autophagic vacuoles, Shoul... OMIM:608423
Breath-Holding Spells
Pallor, Iron deficiency anemia OMIM:607578
Myopathy, Lactic Acidosis, And Sideroblastic Anemia 1
Microcytic anemia, Hypochromic anemia, Sideroblastic anemia, Pappenheimer bodies, Generalized lim... OMIM:600462
Acquired Idiopathic Sideroblastic Anemia
Pancytopenia, Hypochromic anemia, Leukocytosis, Granulocytopenia, Normocytic anemia, Megaloblasti... ORPHA:75564
Retinitis Pigmentosa 42
Pallor OMIM:612943
Acute Peripheral Arterial Occlusion
Pallor, Leukocytosis, Limb muscle weakness ORPHA:90064
Microcytic anemia, Abnormal hemoglobin, Hypertrophic cardiomyopathy, Splenomegaly, Anemia, Pallor... ORPHA:848
Left Ventricular Noncompaction 7
Left ventricular noncompaction cardiomyopathy, Left ventricular noncompaction OMIM:615092
Retinitis Pigmentosa 81
Pallor OMIM:617871
Retinitis Pigmentosa 60
Pallor OMIM:613983
X-Linked Sideroblastic Anemia
Pallor, Anemia, Splenomegaly ORPHA:75563
Isobutyryl-Coa Dehydrogenase Deficiency
Dilated cardiomyopathy, Anemia OMIM:611283
Anemia, Sideroblastic, Pyridoxine-Responsive, Autosomal Recessive
Sideroblastic anemia, Hepatosplenomegaly, Pyridoxine-responsive sideroblastic anemia, Decreased m... OMIM:206000
Anemia, Sideroblastic, 2, Pyridoxine-Refractory
Decreased mean corpuscular volume, Anemia, Hypochromia OMIM:205950
Thiamine-Responsive Megaloblastic Anemia Syndrome
Atrial septal defect, Megaloblastic anemia, Ventricular septal defect, Pallor, Thrombocytopenia ORPHA:49827
Anemia, Hypochromic Microcytic, With Iron Overload 1
Decreased mean corpuscular volume, Anemia, Hypochromia OMIM:206100
Left Ventricular Noncompaction 10
Dilated cardiomyopathy, Left ventricular noncompaction OMIM:615396
Hemoglobin-Delta locus
Anemia, Imbalanced hemoglobin synthesis OMIM:142000
Optic Atrophy 9
Pallor OMIM:616289
Hb Bart'S Hydrops Fetalis
Abnormal hemoglobin, Splenomegaly, Anemia, Pericarditis, Pallor ORPHA:163596
Benign Paroxysmal Torticollis Of Infancy
Pallor, Torticollis ORPHA:71518
Cardiomyopathy, Dilated, 1R
Dilated cardiomyopathy, Left ventricular noncompaction, Left ventricular hypertrophy, Restrictive... OMIM:613424
Cardiomyopathy, Dilated, 1C, With Or Without Left Ventricular Noncompaction
Dilated cardiomyopathy, Left ventricular noncompaction, Left ventricular hypertrophy, Endocardial... OMIM:601493
Eosinophilia, Familial
Eosinophilia, Leukocytosis, Thrombocytopenia, Anemia, Myocardial eosinophilic infiltration OMIM:131400
Peripheral Cone Dystrophy
Pallor OMIM:609021
Methylmalonic Acidemia With Homocystinuria, Type Cbld
Pallor ORPHA:79283
Congenital Amegakaryocytic Thrombocytopenia
Abnormal hemoglobin, Anemia, Thrombocytopenia, Abnormal cardiac septum morphology ORPHA:3319
Retinohepatoendocrinologic Syndrome
Pallor OMIM:268040
Hereditary Spherocytosis
Reticulocytosis, Increased mean corpuscular hemoglobin concentration, Splenomegaly, Spherocytosis... ORPHA:822
Fetal Parvovirus Syndrome
Anemia, Hypertrophic cardiomyopathy, Thrombocytopenia, Intrauterine growth retardation ORPHA:295
Cone-Rod Dystrophy 11
Pallor OMIM:610381
Primary Myelofibrosis
Pancytopenia, Petechiae, Hepatosplenomegaly, Ecchymosis, Leukocytosis, Thrombocytosis, Splenomega... ORPHA:824
Megaloblastic Anemia Due To Dihydrofolate Reductase Deficiency
Pallor, Pancytopenia, Thrombocytopenia, Megaloblastic anemia OMIM:613839
Hemoglobin E-Beta-Thalassemia Syndrome
Abnormal hemoglobin, Anemia ORPHA:231249
Optic Atrophy 7 With Or Without Auditory Neuropathy
Pallor, Hypertrophic cardiomyopathy OMIM:612989
Diamond-Blackfan Anemia 16
Atrial septal defect, Anemia, Pulmonic stenosis OMIM:617408
Elliptocytosis 1
Pallor, Elliptocytosis, Splenomegaly, Hemolytic anemia OMIM:611804
Pancytopenia, Abnormal macrophage morphology, Leukopenia, Splenomegaly, Anemia, Pallor, Skin ulce... ORPHA:507
Anemia, Nonspherocytic Hemolytic, Due To G6Pd Deficiency
Fava bean-induced hemolytic anemia, Reticulocytosis, Leukocytosis, Anisocytosis, Splenomegaly, He... OMIM:300908
Primary Lateral Sclerosis, Juvenile
Pallor, Spasticity of facial muscles OMIM:606353
Myopathic Ehlers-Danlos Syndrome
Flexion contracture, Contractures involving the joints of the feet, Elbow flexion contracture, Mu... ORPHA:536516
Left Ventricular Noncompaction 1
Left ventricular noncompaction, Patent ductus arteriosus, Left ventricular noncompaction cardiomy... OMIM:604169
Retinitis Pigmentosa 70
Pallor OMIM:615922
Auditory Neuropathy And Optic Atrophy
Pallor OMIM:617717
Congenital Dyserythropoietic Anemia Type Iii
Anisocytosis, Anemia, Increased mean corpuscular volume, Abnormal erythrocyte morphology, Pallor,... ORPHA:98870
Optic Atrophy 1
Pallor OMIM:165500
Imerslund-Gräsbeck Syndrome
Pancytopenia, Hypersegmentation of neutrophil nuclei, Reticulocytosis, Megaloblastic anemia, Abno... ORPHA:35858
Renal Tubular Acidosis, Distal, 4, With Hemolytic Anemia
Reticulocytosis, Hepatosplenomegaly, Hemolytic anemia, Pallor, Decreased mean corpuscular volume OMIM:611590
Hemoglobin E Disease
Intrauterine growth retardation, Splenomegaly, Increased red blood cell count, Abnormal hemoglobi... ORPHA:2133
Cardiomyopathy, Dilated, 1Aa, With Or Without Left Ventricular Noncompaction
Dilated cardiomyopathy, Left ventricular noncompaction, Endocardial fibroelastosis, Cardiomyocyte... OMIM:612158
Dermatitis, Atopic
Pallor, Dry skin, Facial erythema OMIM:603165
Evans Syndrome
Petechiae, Autoimmune thrombocytopenia, Autoimmune hemolytic anemia, Neutropenia in presence of a... ORPHA:1959
Osteoporosis-Oculocutaneous Hypopigmentation Syndrome
Pallor ORPHA:2786
Retinitis Pigmentosa 27
Pallor OMIM:613750
Thanatophoric Dysplasia, Glasgow Variant
Neonatal death, Anemia, Hepatosplenomegaly OMIM:273680
Retinitis Pigmentosa And Erythrocytic Microcytosis
Anisocytosis, Anemia, Elliptocytosis, Pallor, Decreased mean corpuscular volume, Poikilocytosis OMIM:616959
Cyclic Vomiting Syndrome
Pallor, Cardiomyopathy OMIM:500007
Cardiomyopathy, Dilated, 1D
Dilated cardiomyopathy, Left ventricular noncompaction, Left ventricular hypertrophy OMIM:601494
Autoimmune Hemolytic Anemia
Pallor, Splenomegaly, Abnormal leukocyte morphology, Hemolytic anemia ORPHA:98375
Left Ventricular Noncompaction 8
Left ventricular noncompaction, Dilated cardiomyopathy, Abnormal left ventricle morphology OMIM:615373
Hemoglobin C-Beta-Thalassemia Syndrome
Microcytic anemia, Anemia, Splenomegaly, Abnormal hemoglobin ORPHA:231242
Retinitis Pigmentosa 73
Pallor OMIM:616544
Hemolytic Anemia Due To Red Cell Pyruvate Kinase Deficiency
Splenomegaly, Anisocytosis, Reduced red cell pyruvate kinase level, Anemia, Chronic hemolytic ane... ORPHA:766
Beta-Thalassemia-X-Linked Thrombocytopenia Syndrome
Abnormal hemoglobin, Anemia, Splenomegaly, Thrombocytopenia ORPHA:231393
Severe Congenital Hypochromic Anemia With Ringed Sideroblasts
Hepatosplenomegaly, Anemia, Anisopoikilocytosis, Dysplastic erythropoesis, Pallor, Reticulocytope... ORPHA:300298
Hereditary Folate Malabsorption
Pancytopenia, Eosinophilia, Skeletal muscle atrophy, Megaloblastic anemia, Pallor, Thrombocytopenia ORPHA:90045
Dehydrated Hereditary Stomatocytosis 1 With Or Without Pseudohyperkalemia And/Or Perinatal Edema
Reticulocytosis, Exercise-induced hemolysis, Splenomegaly, Increased mean corpuscular hemoglobin ... OMIM:194380
Microcytic anemia, Anemia, Abnormal hemoglobin ORPHA:231237
Leber Congenital Amaurosis 14
Pallor OMIM:613341
Cold Agglutinin Disease
Pallor, Splenomegaly, Hemolytic anemia ORPHA:56425
Beta-Thalassemia Major
Dilated cardiomyopathy, Hepatosplenomegaly, Decreased mean corpuscular hemoglobin concentration, ... ORPHA:231214
Dominant Beta-Thalassemia
Dilated cardiomyopathy, Hepatosplenomegaly, Decreased mean corpuscular hemoglobin concentration, ... ORPHA:231226
Combined Oxidative Phosphorylation Deficiency 31
Left ventricular noncompaction, Hypertrophic cardiomyopathy OMIM:617228
Hyperinsulinism Due To Ucp2 Deficiency
Pallor, Hypertrophic cardiomyopathy ORPHA:276556
Drug-Induced Autoimmune Hemolytic Anemia
Pallor, Autoimmune hemolytic anemia, Splenomegaly ORPHA:90037
Bleeding Disorder, Platelet-Type, 16
Petechiae, Macrothrombocytopenia, Platelet anisocytosis, Giant platelets, Anemia, Thrombocytopenia OMIM:187800
Pancytopenia And Occlusive Vascular Disease
Pancytopenia, Anemia, Leukopenia, Thrombocytopenia OMIM:167850
Rheumatic Fever
Abnormal heart valve morphology, Abnormal mitral valve morphology, Erythema, Myocarditis, Abnorma... ORPHA:3099
Autosomal Dominant Hyperinsulinism Due To Sur1 Deficiency
Pallor, Hypertrophic cardiomyopathy ORPHA:276575
Erythroleukemia, Familial, Susceptibility To
Leukemia, Acute myeloid leukemia, Splenomegaly, Anemia, Erythroid hyperplasia, Thrombocytopenia OMIM:133180
Beta-Thalassemia Intermedia
Hepatosplenomegaly, Leukocytosis, Anemia of inadequate production, Splenomegaly, Persistence of h... ORPHA:231222
Autosomal Dominant Hyperinsulinism Due To Kir6.2 Deficiency
Pallor, Hypertrophic cardiomyopathy ORPHA:276580
Neutropenia, Severe Congenital, 5, Autosomal Recessive
Leukopenia, Splenomegaly, Neutropenia, Anemia, Thrombocytopenia, Extramedullary hematopoiesis OMIM:615285
Letterer-Siwe Disease
Hepatosplenomegaly, Neutropenia, Anemia, Pallor, Thrombocytopenia OMIM:246400
Mitochondrial Complex Ii Deficiency, Nuclear Type 1
Dilated cardiomyopathy, Left ventricular noncompaction, Flexion contracture, Ragged-red muscle fi... OMIM:252011
Pallor, Myeloproliferative disorder, Purpura, Splenomegaly OMIM:254450
Anemia, Congenital Dyserythropoietic, Type Iv
Schistocytosis, Reticulocytosis, Circulating nucleated red blood cells, Hepatosplenomegaly, Poiki... OMIM:613673
Idiopathic Pulmonary Hemosiderosis
Pallor, Cardiomegaly, Hepatosplenomegaly, Iron deficiency anemia ORPHA:99931
Deafness-Lymphedema-Leukemia Syndrome
Leukocytosis, Abnormal neutrophil count, Myeloproliferative disorder, Splenomegaly, Acute leukemi... ORPHA:3226
Formiminoglutamic Aciduria
Atrial septal defect, Megaloblastic anemia, Anemia ORPHA:51208
Anemia, Sideroblastic, 5
Neutropenia, Anemia, Thrombocytopenia, Reduced hematocrit, Hypochromic microcytic anemia OMIM:619523
Dyserythropoiesis, Congenital, With Ultrastructurally Normal Erythroblast Heterochromatin
Anemia of inadequate production, Oval macrocytosis, Anisocytosis, Poikilocytosis OMIM:603529
Aregenerative Anemia
Pancytopenia, Decreased proportion of CD4-positive helper T cells, Abnormal proportion of CD8-pos... ORPHA:101096
American Trypanosomiasis
Pallor, Cardiomyopathy, Myocarditis, Splenomegaly ORPHA:3386
Hemochromatosis, Type 3
Neutropenia, Anemia, Cardiomyopathy, Lymphopenia, Purpura OMIM:604250
Familial Focal Epilepsy With Variable Foci
Pallor ORPHA:98820
Transaldolase Deficiency
Hepatosplenomegaly, Atrial septal defect, Biventricular hypertrophy, Anemia, Premature skin wrink... ORPHA:101028
Non-Insulinoma Pancreatogenous Hypoglycemia Syndrome
Pallor ORPHA:276608
Cyanosis, Transient Neonatal
Reticulocytosis, Anemia, Methemoglobinemia OMIM:613977
Plummer-Vinson Syndrome
Pallor, Iron deficiency anemia, Hypochromic microcytic anemia ORPHA:54028
Systemic Mastocytosis With Associated Hematologic Neoplasm
Eosinophilia, Abnormal mast cell morphology, Leukocytosis, Normocytic anemia, Chronic myelomonocy... ORPHA:98849
Mixed-Type Autoimmune Hemolytic Anemia
Pallor, Autoimmune hemolytic anemia ORPHA:90036
Diamond-Blackfan Anemia 20
Anemia, Erythroid hypoplasia, Total anomalous pulmonary venous return OMIM:618313
Fanconi Anemia, Complementation Group I
Intrauterine growth retardation, Patent foramen ovale, Atrial septal defect, Neutropenia, Ventric... OMIM:609053
Neutropenia, Severe Congenital, 1, Autosomal Dominant
Eosinophilia, Monocytosis, Thrombocytosis, Congenital agranulocytosis, Neutropenia, Anemia, Acute... OMIM:202700
Autoimmune Hemolytic Anemia, Warm Type
Pallor, Autoimmune hemolytic anemia, Splenomegaly, Chronic lymphatic leukemia ORPHA:90033
Acute Erythroid Leukemia
Pancytopenia, Anemia, Leukopenia, Erythroid hypoplasia ORPHA:318
Microcytic anemia, Splenomegaly, Anemia, Hemolytic anemia, Abnormal hemoglobin, Hypersplenism ORPHA:846
Spontaneous Periodic Hypothermia
Pallor ORPHA:29822
Severe Combined Immunodeficiency Due To Complete Rag1/2 Deficiency
Eosinophilia, Decreased proportion of CD3-positive T cells, Hepatosplenomegaly, Autoimmune hemoly... ORPHA:331206
3-Hydroxy-3-Methylglutaryl-Coa Lyase Deficiency
Pallor, Anemia OMIM:246450
Refractory Anemia With Excess Blasts
Anemic pallor, Leukocytosis, Acute myeloid leukemia, Abnormal mean corpuscular volume, Anemia of ... ORPHA:86839
Blackfan-Diamond Anemia
Leukopenia, Atrial septal defect, Thrombocytosis, Abnormality of the thenar eminence, Erythroid h... ORPHA:124
Thrombocytopenia 5
Neutropenia, Anemia, Petechiae, Thrombocytopenia OMIM:616216
Monosomy 7 Myelodysplasia And Leukemia Syndrome 2
Pancytopenia, Acute myeloid leukemia, Neutropenia, Anemia, Increased mean corpuscular volume, Thr... OMIM:619041
Glycogen Storage Disease Due To Muscle Phosphofructokinase Deficiency
Anemia, Increased muscle glycogen content, Skeletal muscle atrophy ORPHA:371
Mitochondrial Complex Iv Deficiency, Nuclear Type 13
Hypertrophic cardiomyopathy, Left ventricular noncompaction, Patent ductus arteriosus OMIM:616501
Anemia, Sideroblastic, 1
Anemia of inadequate production, Sideroblastic anemia, Hypochromic microcytic anemia, Macrocytic ... OMIM:300751
Osteopetrosis, Autosomal Recessive 4
Petechiae, Hepatosplenomegaly, Splenomegaly, Anemia, Reticulocytosis, Facial palsy, Thrombocytopenia OMIM:611490
Hyperinsulinism Due To Hnf1A Deficiency
Pallor ORPHA:324575
Pearson Marrow-Pancreas Syndrome
Pancytopenia, Refractory sideroblastic anemia, Sideroblastic anemia, Hypoplastic anemia, Erythema... OMIM:557000
Neutrophilic Dermatosis, Acute Febrile
Dilated cardiomyopathy, Pyoderma gangrenosum, Erythema, Anemia OMIM:608068
Retinitis Pigmentosa 51
Pallor OMIM:613464
Dohle Bodies And Leukemia
Anemia, Acute myeloid leukemia, Leukocyte inclusion bodies, Secundum atrial septal defect OMIM:223350
Fanconi Anemia, Complementation Group E
Pancytopenia, Anemic pallor, Leukemia, Neutropenia, Abnormal heart morphology, Anemia, Reticulocy... OMIM:600901
Fanconi Anemia, Complementation Group A
Pancytopenia, Anemic pallor, Leukemia, Neutropenia, Abnormal heart morphology, Anemia, Reticulocy... OMIM:227650
Fanconi Anemia, Complementation Group C
Pancytopenia, Anemic pallor, Flexion contracture, Intrauterine growth retardation, Leukemia, Neut... OMIM:227645
Sepsis In Premature Infants
Petechiae, Leukocytosis, Splenomegaly, Thrombocytopenia, Neutropenia, Anemia, Pallor, Purpura ORPHA:90051
Combined Oxidative Phosphorylation Deficiency 42
Neonatal death, Anemia, Cardiomyopathy, Intrauterine growth retardation OMIM:618839
Combined Oxidative Phosphorylation Deficiency 40
Neonatal death, Anemia, Hypertrophic cardiomyopathy, Intrauterine growth retardation OMIM:618835
3-Hydroxy-3-Methylglutaric Aciduria
Dilated cardiomyopathy, Leukopenia, Leukocytosis, Thrombocytosis, Anemia, Pallor ORPHA:20
Myoclonus, Intractable, Neonatal
Pallor OMIM:617235
Diamond-Blackfan Anemia 1
Intrauterine growth retardation, Congenital hypoplastic anemia, Atrial septal defect, Thrombocyto... OMIM:105650
Combined Oxidative Phosphorylation Deficiency 41
Cardiomegaly, Intrauterine growth retardation, Anemia OMIM:618838
Irida Syndrome
Pallor ORPHA:209981
Anemia, Sideroblastic, 3, Pyridoxine-Refractory
Hepatosplenomegaly, Anisocytosis, Splenomegaly, Anemia, Erythroid hyperplasia, Decreased mean cor... OMIM:616860
Non-Functioning Paraganglioma
Pallor ORPHA:94080
Dravet Syndrome
Pallor ORPHA:33069
Kcnq2-Related Epileptic Encephalopathy
Pallor, Facial erythema ORPHA:439218
Waldenström Macroglobulinemia
Normocytic anemia, Leukemia, Splenomegaly, Abnormality of neutrophils, Pallor, Purpura ORPHA:33226
Attrv122I Amyloidosis
Tendon rupture, Cardiac amyloidosis, Hypertrophic cardiomyopathy, Anemia, Restrictive cardiomyopa... ORPHA:85451
Fumarase Deficiency
Pallor, Polycythemia OMIM:606812
Retinitis Pigmentosa 75
Pallor OMIM:617023
Generalized Juvenile Polyposis/Juvenile Polyposis Coli
Anemia, Anemic pallor ORPHA:329971
Mitochondrial Complex Ii Deficiency, Nuclear Type 3
Dilated cardiomyopathy, Left ventricular noncompaction, Patent foramen ovale, Neonatal death, Lef... OMIM:619167
Myopathy, Mitochondrial, And Ataxia
Pallor, Increased variability in muscle fiber diameter, Distal amyotrophy OMIM:617675
Idiopathic Hypereosinophilic Syndrome
Dilated cardiomyopathy, Eosinophilia, Hepatosplenomegaly, Leukocytosis, Skeletal muscle atrophy, ... ORPHA:3260
Idiopathic Aplastic Anemia
Pancytopenia, Ecchymosis, Neutropenia, Anemia, Reticulocytopenia, Thrombocytopenia ORPHA:88
Senior-Loken Syndrome 8
Pallor OMIM:616307
Thrombocytopenia, Anemia, And Myelofibrosis
Anemia, Splenomegaly, Thrombocytopenia, Anisopoikilocytosis OMIM:617441
Atrial Standstill
Left ventricular noncompaction, Flexion contracture, Skeletal muscle atrophy, Muscular dystrophy,... ORPHA:1344
Fanconi Anemia, Complementation Group D2
Pancytopenia, Anemic pallor, Leukemia, Patent ductus arteriosus, Neutropenia, Abnormal heart morp... OMIM:227646
6-Pyruvoyl-Tetrahydropterin Synthase Deficiency
Pallor ORPHA:13
Hyperinsulinism Due To Hnf4A Deficiency
Pallor ORPHA:263455
Beta-Ketothiolase Deficiency
Pallor, Leukocytosis, Thrombocytosis ORPHA:134
Pallor, Normochromic anemia ORPHA:95512
Sick Sinus Syndrome 2
Left ventricular noncompaction, Left ventricular hypertrophy, Mitral valve prolapse OMIM:163800
Non-Functioning Pituitary Adenoma
Pallor, Anemia of inadequate production ORPHA:91349
Pituitary Apoplexy
Pallor, Normochromic anemia ORPHA:95613
Tay-Sachs Disease
Pallor OMIM:272800
Pallor, Normochromic anemia ORPHA:95513
Rare Circulatory System Disease
Pallor, Elbow flexion contracture ORPHA:98028
Cone-Rod Dystrophy 8
Pallor OMIM:605549
Sheehan Syndrome
Pallor, Normochromic anemia, Dry skin ORPHA:91355
Von Hippel-Lindau Disease
Distal lower limb muscle weakness, Myocarditis, Upper limb muscle weakness, Cardiomyopathy, Polyc... ORPHA:892
Degcags Syndrome
Pancytopenia, Hepatosplenomegaly, Intrauterine growth retardation, Patent ductus arteriosus, Pate... OMIM:619488
Fructose-1,6-Bisphosphatase Deficiency
Pallor ORPHA:348
Childhood Absence Epilepsy
Pallor ORPHA:64280
Sporadic Pheochromocytoma/Secreting Paraganglioma
Pallor ORPHA:276621
Infection-Related Hemolytic Uremic Syndrome
Leukocytosis, Myocarditis, Hemolytic anemia, Pallor, Thrombocytopenia ORPHA:544482
Autosomal Recessive Malignant Osteopetrosis
Pallor, Anemia, Abnormal pulmonary valve morphology, Splenomegaly ORPHA:667
Incontinentia Pigmenti
Pallor, Eosinophilia, Erythema, Leukocytosis OMIM:308300
Alternating Hemiplegia Of Childhood
Pallor, Cardiomyopathy, Facial hypotonia ORPHA:2131
Tangier Disease
Left ventricular hypertrophy, Coronary artery stenosis, Hepatosplenomegaly, Anemia, Facial dipleg... ORPHA:31150
Naxos Disease
Cardiomegaly, Right ventricular cardiomyopathy, Dilated cardiomyopathy, Abnormal morphology of ri... OMIM:601214
Cardiomyopathy, Dilated, 1S
Interstitial cardiac fibrosis, Dilated cardiomyopathy, Left ventricular noncompaction, Bicuspid a... OMIM:613426
Pallor ORPHA:2965
Hereditary Pheochromocytoma-Paraganglioma
Pallor ORPHA:29072
Congenital Total Pulmonary Venous Return Anomaly
Patent ductus arteriosus, Atrial septal defect, Supracardiac total anomalous pulmonary venous con... ORPHA:99125
Histiocytoid Cardiomyopathy
Pallor, Cardiomegaly, Ventricular septal defect ORPHA:137675
Esophageal Atresia
Pallor, Tetralogy of Fallot, Ventricular septal defect ORPHA:1199
Multiple Endocrine Neoplasia Type 2
Pallor, Proximal amyotrophy ORPHA:653
Tsh-Secreting Pituitary Adenoma
Pallor, Pericardial effusion ORPHA:91347
Intellectual Developmental Disorder, X-Linked, Syndromic 34
Left ventricular noncompaction, Patent foramen ovale, Patent ductus arteriosus, Atrial septal def... OMIM:300967
Muscular Dystrophy-Dystroglycanopathy (Congenital With Brain And Eye Anomalies), Type A, 3
Pallor, Muscular dystrophy OMIM:253280
Visceral Steatosis, Congenital
Neonatal death, Myocardial steatosis OMIM:228100
Goodpasture Syndrome
Pallor, Anemia OMIM:233450
Homozygous Familial Hypercholesterolemia
Abnormal tendon morphology, Myocardial steatosis, Tendon xanthomatosis ORPHA:391665
Cerebral Cavernous Malformations 3
Familial Cerebral Cavernous Malformation


Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Pdcd10

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Pdcd10.

No publications found that use IMPC mice or data for Pdcd10.

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MGI Allele Allele Type Produced
Pdcd10tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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