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Gene: Pdcd10 MGI:1928396

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Not currently registered for phenotyping at IMPC

Phenotyping is currently not planned for a knockout strain of this gene.

Gene Summary

Name:
programmed cell death 10
Synonyms:
Tfa15,  CCM3,  TF-1 cell apoptosis related protein-15,  2410003B13Rik

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IMPC Data Collections

  • No Body Weight Data
  • No Embryo Imaging Data
  • No Viability Data

IMPC Phenotype Summary

Significant
Not Significant
Not tested

View all our phenotype data below

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Legacy Phenotype Associated Images
Pdcd10tm1a(KOMP)Wtsi
WT, Female, WTSI
Pdcd10tm1a(KOMP)Wtsi
WT, Female, WTSI
Pdcd10tm1a(KOMP)Wtsi
WT, Female, WTSI
Pdcd10tm1a(KOMP)Wtsi
WT, Female, WTSI
Pdcd10tm1a(KOMP)Wtsi
WT, Female, WTSI

View all 32 images

Human diseases caused by Pdcd10 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

The table below shows human diseases associated to Pdcd10 by orthology or direct annotation.

Disease Similarity of
phenotypes		 Matching phenotypes Source
Familial Cerebral Cavernous Malformation
ORPHA:221061
Cerebral Cavernous Malformations 3
OMIM:603285

The table below shows human diseases predicted to be associated to Pdcd10 by phenotypic similarity.

Disease Similarity of
phenotypes		 Matching phenotypes Source
Hemoglobin D Disease
Reduced beta/alpha synthesis ratio, Reduced hemoglobin A, Imbalanced hemoglobin synthesis, Pallor... ORPHA:90039
Hereditary Persistence Of Fetal Hemoglobin-Beta-Thalassemia Syndrome
Anemia, Pallor, Splenomegaly, Persistence of hemoglobin F ORPHA:46532
Diamond-Blackfan Anemia 19
Anemia, Erythroid hypoplasia, Steroid-responsive anemia OMIM:618312
Transient Erythroblastopenia Of Childhood
Anemia, Transient erythroblastopenia OMIM:227050
Anemia, Congenital Dyserythropoietic, Type Ib
Erythroid hyperplasia, Pallor, Splenomegaly, Anemia of inadequate production, Anisocytosis, Retic... OMIM:615631
Acute Myelomonocytic Leukemia
Pallor, Leukocytosis, Eosinophilia, Thrombocytopenia, Anemia ORPHA:517
Breath-Holding Spells
Iron deficiency anemia, Pallor OMIM:607578
Anemia, Sideroblastic, 1
Sideroblastic anemia, Anemia of inadequate production, Macrocytic anemia, Anemic pallor, Hypochro... OMIM:300751
Acquired Idiopathic Sideroblastic Anemia
Normocytic anemia, Megaloblastic erythroid hyperplasia, Hypochromic anemia, Pancytopenia, Erythro... ORPHA:75564
Cardiomyopathy, Dilated, 1R
Restrictive cardiomyopathy, Dilated cardiomyopathy, Cardiomyocyte hypertrophy, Left ventricular n... OMIM:613424
Acute Peripheral Arterial Occlusion
Leukocytosis, Limb muscle weakness, Pallor ORPHA:90064
Beta-Thalassemia
Skin ulcer, Microcytic anemia, Hypertrophic cardiomyopathy, Pallor, Splenomegaly, Abnormal hemogl... ORPHA:848
Left Ventricular Noncompaction 7
Left ventricular noncompaction, Left ventricular noncompaction cardiomyopathy OMIM:615092
Myopathy, Lactic Acidosis, And Sideroblastic Anemia 2
Hypertrophic cardiomyopathy, Sideroblastic anemia, Pallor, Ragged-red muscle fibers, Generalized ... OMIM:613561
X-Linked Sideroblastic Anemia
Anemia, Pallor, Splenomegaly ORPHA:75563
Isobutyryl-Coa Dehydrogenase Deficiency
Anemia, Dilated cardiomyopathy OMIM:611283
Anemia, Hypochromic Microcytic, With Iron Overload 2
Sideroblastic anemia, Pallor, Splenomegaly, Hypochromia, Poikilocytosis, Anemia, Decreased mean c... OMIM:615234
Hb Bart'S Hydrops Fetalis
Pallor, Splenomegaly, Abnormal hemoglobin, Anemia, Pericarditis ORPHA:163596
Thiamine-Responsive Megaloblastic Anemia Syndrome
Pallor, Ventricular septal defect, Megaloblastic anemia, Atrial septal defect, Thrombocytopenia ORPHA:49827
Anemia, Sideroblastic, 2, Pyridoxine-Refractory
Anemia, Sideroblastic anemia, Decreased mean corpuscular volume, Hypochromia OMIM:205950
Hemoglobin-Delta locus
Anemia, Imbalanced hemoglobin synthesis OMIM:142000
Benign Paroxysmal Torticollis Of Infancy
Pallor, Torticollis ORPHA:71518
Optic Atrophy 7 With Or Without Auditory Neuropathy
Hypertrophic cardiomyopathy, Pallor OMIM:612989
Pyruvate Kinase Deficiency Of Red Cells
Reduced red cell pyruvate kinase level, Erythroid hyperplasia, Intrauterine growth retardation, P... OMIM:266200
Methylmalonic Acidemia With Homocystinuria, Type Cbld
Pallor ORPHA:79283
Myopathy, Lactic Acidosis, And Sideroblastic Anemia 1
Hypochromic anemia, Generalized limb muscle atrophy, Microcytic anemia, Sideroblastic anemia, Pap... OMIM:600462
Primary Myelofibrosis
Extramedullary hematopoiesis, Hepatosplenomegaly, Pancytopenia, Leukocytosis, Splenomegaly, Throm... ORPHA:824
Peripheral Cone Dystrophy
Pallor OMIM:609021
Cone-Rod Dystrophy 11
Pallor OMIM:610381
Eosinophilia, Familial
Leukocytosis, Eosinophilia, Thrombocytopenia, Myocardial eosinophilic infiltration, Anemia OMIM:131400
Cardiomyopathy, Dilated, 1Aa, With Or Without Left Ventricular Noncompaction
Dilated cardiomyopathy, Endocardial fibrosis, Cardiomyocyte hypertrophy, Hypertrophic cardiomyopa... OMIM:612158
Fetal Parvovirus Syndrome
Anemia, Intrauterine growth retardation, Hypertrophic cardiomyopathy, Thrombocytopenia ORPHA:295
Hereditary Spherocytosis
Spontaneous hemolytic crises, Restrictive cardiomyopathy, Increased mean corpuscular hemoglobin c... ORPHA:822
Hemoglobin E Disease
Increased red blood cell count, Reduced hemoglobin A, Drug-sensitive hemolytic anemia, Intrauteri... ORPHA:2133
Hemoglobin E-Beta-Thalassemia Syndrome
Anemia, Abnormal hemoglobin ORPHA:231249
Diamond-Blackfan Anemia 16
Anemia, Atrial septal defect, Pulmonic stenosis OMIM:617408
Leishmaniasis
Skin ulcer, Pancytopenia, Leukopenia, Pallor, Splenomegaly, Abnormal macrophage morphology, Throm... ORPHA:507
Cardiomyopathy, Dilated, 1Gg
Left ventricular noncompaction, Dilated cardiomyopathy OMIM:613642
Myopathic Ehlers-Danlos Syndrome
Increased variability in muscle fiber diameter, Joint contracture of the hand, Ankle flexion cont... ORPHA:536516
Congenital Dyserythropoietic Anemia Type Iii
Increased mean corpuscular volume, Abnormal erythrocyte morphology, Pallor, Anisocytosis, Poikilo... ORPHA:98870
Elliptocytosis 1
Hemolytic anemia, Splenomegaly, Pallor, Elliptocytosis OMIM:611804
Evans Syndrome
Pallor, Petechiae, Autoimmune hemolytic anemia, Neutropenia in presence of anti-neutropil antibod... ORPHA:1959
Cardiomyopathy, Dilated, 1C, With Or Without Left Ventricular Noncompaction
Left ventricular noncompaction, Left ventricular hypertrophy, Dilated cardiomyopathy, Endocardial... OMIM:601493
Dermatitis, Atopic
Dry skin, Facial erythema, Pallor OMIM:603165
Imerslund-Gräsbeck Syndrome
Anisopoikilocytosis, Hypersegmentation of neutrophil nuclei, Pancytopenia, Pallor, Reticulocytosi... ORPHA:35858
Renal Tubular Acidosis, Distal, 4, With Hemolytic Anemia
Hepatosplenomegaly, Pallor, Reticulocytosis, Decreased mean corpuscular volume, Hemolytic anemia OMIM:611590
Left Ventricular Noncompaction 1
Hypoplastic left heart, Left ventricular noncompaction, Left ventricular noncompaction cardiomyop... OMIM:604169
Anemia, Nonspherocytic Hemolytic, Due To G6Pd Deficiency
Leukocytosis, Reticulocytosis, Splenomegaly, Anisocytosis, Heinz bodies, Fava bean-induced hemoly... OMIM:300908
Left Ventricular Noncompaction 10
Left ventricular noncompaction, Dilated cardiomyopathy OMIM:615396
Primary Lateral Sclerosis, Juvenile
Spasticity of facial muscles, Pallor OMIM:606353
Anemia, Sideroblastic, And Spinocerebellar Ataxia
Howell-Jolly bodies, Sideroblastic anemia, Pappenheimer bodies, Erythroid hyperplasia, Intrauteri... OMIM:301310
Megaloblastic Anemia Due To Dihydrofolate Reductase Deficiency
Increased mean corpuscular volume, Pancytopenia, Pallor, Megaloblastic anemia, Thrombocytopenia OMIM:613839
Congenital Heart Block
Intrauterine growth retardation, Endocardial fibroelastosis, Pallor, Patent foramen ovale, Perica... ORPHA:60041
Myelofibrosis
Hemophagocytosis, Extramedullary hematopoiesis, Pallor, Splenomegaly, Myeloproliferative disorder... OMIM:254450
Osteoporosis-Oculocutaneous Hypopigmentation Syndrome
Pallor ORPHA:2786
Cyclic Vomiting Syndrome
Pallor, Cardiomyopathy OMIM:500007
Leber Congenital Amaurosis 14
Pallor OMIM:613341
Hereditary Folate Malabsorption
Skeletal muscle atrophy, Pancytopenia, Pallor, Eosinophilia, Megaloblastic anemia, Thrombocytopenia ORPHA:90045
Thanatophoric Dysplasia, Glasgow Variant
Anemia, Hepatosplenomegaly, Neonatal death OMIM:273680
Dehydrated Hereditary Stomatocytosis 1 With Or Without Pseudohyperkalemia And/Or Perinatal Edema
Increased mean corpuscular hemoglobin concentration, Pallor, Splenomegaly, Increased red cell hem... OMIM:194380
Severe Congenital Hypochromic Anemia With Ringed Sideroblasts
Hepatosplenomegaly, Pallor, Reticulocytopenia, Dysplastic erythropoesis, Anisopoikilocytosis, Ane... ORPHA:300298
Hemoglobin C-Beta-Thalassemia Syndrome
Anemia, Splenomegaly, Microcytic anemia, Abnormal hemoglobin ORPHA:231242
Dominant Beta-Thalassemia
Hypoplasia of the musculature, Dilated cardiomyopathy, Reduced hemoglobin A, Extramedullary hemat... ORPHA:231226
Beta-Thalassemia-X-Linked Thrombocytopenia Syndrome
Anemia, Splenomegaly, Thrombocytopenia, Abnormal hemoglobin ORPHA:231393
Optic Atrophy 1
Pallor OMIM:165500
Left Ventricular Noncompaction 8
Left ventricular noncompaction, Dilated cardiomyopathy OMIM:615373
Hemolytic Anemia Due To Red Cell Pyruvate Kinase Deficiency
Reduced red cell pyruvate kinase level, Congenital hemolytic anemia, Abnormal erythrocyte morphol... ORPHA:766
Cold Agglutinin Disease
Hemolytic anemia, Splenomegaly, Pallor ORPHA:56425
Beta-Thalassemia Major
Hypoplasia of the musculature, Dilated cardiomyopathy, Reduced hemoglobin A, Extramedullary hemat... ORPHA:231214
Mitochondrial Complex I Deficiency, Nuclear Type 39
Hypertrophic cardiomyopathy, Intrauterine growth retardation, Cardiomegaly, Perimembranous ventri... OMIM:620135
Delta-Beta-Thalassemia
Anemia, Microcytic anemia, Abnormal hemoglobin ORPHA:231237
Bleeding Disorder, Platelet-Type, 16
Platelet anisocytosis, Giant platelets, Petechiae, Thrombocytopenia, Anemia, Macrothrombocytopenia OMIM:187800
Hyperinsulinism Due To Ucp2 Deficiency
Hypertrophic cardiomyopathy, Pallor ORPHA:276556
Drug-Induced Autoimmune Hemolytic Anemia
Pallor, Splenomegaly, Autoimmune hemolytic anemia ORPHA:90037
Beta-Thalassemia Intermedia
Skin ulcer, Extramedullary hematopoiesis, Persistence of hemoglobin F, Hepatosplenomegaly, Erythr... ORPHA:231222
Familial Focal Epilepsy With Variable Foci
Pallor ORPHA:98820
Idiopathic Pulmonary Hemosiderosis
Cardiomegaly, Hepatosplenomegaly, Iron deficiency anemia, Pallor ORPHA:99931
Autosomal Dominant Hyperinsulinism Due To Sur1 Deficiency
Hypertrophic cardiomyopathy, Pallor ORPHA:276575
Erythroleukemia, Familial, Susceptibility To
Erythroid hyperplasia, Splenomegaly, Anemia, Acute myeloid leukemia, Thrombocytopenia, Leukemia OMIM:133180
Rheumatic Fever
Erythema, Abnormal heart valve morphology, Pallor, Abnormal aortic valve morphology, Abnormal mit... ORPHA:3099
Autosomal Dominant Hyperinsulinism Due To Kir6.2 Deficiency
Hypertrophic cardiomyopathy, Pallor ORPHA:276580
Deafness-Lymphedema-Leukemia Syndrome
Acute leukemia, Leukocytosis, Splenomegaly, Pallor, Thrombocytopenia, Abnormal neutrophil count, ... ORPHA:3226
Letterer-Siwe Disease
Hepatosplenomegaly, Pallor, Neutropenia, Thrombocytopenia, Anemia OMIM:246400
Combined Oxidative Phosphorylation Deficiency 31
Left ventricular noncompaction, Increased variability in muscle fiber diameter, Increased intramy... OMIM:617228
Anemia, Congenital Dyserythropoietic, Type Iv
Increased RBC distribution width, Persistence of hemoglobin F, Hypertrophic cardiomyopathy, Hepat... OMIM:613673
Mitochondrial Complex Ii Deficiency, Nuclear Type 1
Dilated cardiomyopathy, Left ventricular noncompaction, Hypertrophic cardiomyopathy, Ragged-red m... OMIM:252011
American Trypanosomiasis
Myocarditis, Pallor, Splenomegaly, Cardiomyopathy ORPHA:3386
Transaldolase Deficiency
Premature skin wrinkling, Biventricular hypertrophy, Hepatosplenomegaly, Atrial septal defect, Th... ORPHA:101028
Aregenerative Anemia
Pancytopenia, Decreased proportion of CD4-positive helper T cells, Pallor, Abnormal proportion of... ORPHA:101096
Plummer-Vinson Syndrome
Iron deficiency anemia, Pallor, Hypochromic microcytic anemia ORPHA:54028
Non-Insulinoma Pancreatogenous Hypoglycemia Syndrome
Pallor ORPHA:276608
Anemia, Sideroblastic, 5
Reduced hematocrit, Hypochromic microcytic anemia, Thrombocytopenia, Anemia, Neutropenia OMIM:619523
Thrombocytopenia 5
Increased mean corpuscular volume, B Acute Lymphoblastic Leukemia, Petechiae, Neutropenia, Thromb... OMIM:616216
Dyserythropoiesis, Congenital, With Ultrastructurally Normal Erythroblast Heterochromatin
Poikilocytosis, Oval macrocytosis, Anemia of inadequate production, Anisocytosis OMIM:603529
Mixed-Type Autoimmune Hemolytic Anemia
Pallor, Autoimmune hemolytic anemia ORPHA:90036
Systemic Mastocytosis With Associated Hematologic Neoplasm
Normocytic anemia, Chronic myelomonocytic leukemia, Leukocytosis, Splenomegaly, Pallor, Chronic l... ORPHA:98849
Fanconi Anemia, Complementation Group I
Intrauterine growth retardation, Pallor, Patent foramen ovale, Ventricular septal defect, Atrial ... OMIM:609053
Spontaneous Periodic Hypothermia
Pallor ORPHA:29822
Formiminoglutamic Aciduria
Anemia, Megaloblastic anemia, Atrial septal defect ORPHA:51208
Severe Combined Immunodeficiency Due To Complete Rag1/2 Deficiency
Abnormal T cell count, Lymphopenia, Hepatosplenomegaly, Decreased proportion of CD3-positive T ce... ORPHA:331206
Mitochondrial Complex Iv Deficiency, Nuclear Type 13
Hypertrophic cardiomyopathy, Left ventricular noncompaction, Patent ductus arteriosus OMIM:616501
Autoimmune Hemolytic Anemia, Warm Type
Chronic lymphatic leukemia, Pallor, Splenomegaly, Autoimmune hemolytic anemia ORPHA:90033
Refractory Anemia With Excess Blasts
Abnormal mean corpuscular volume, Leukocytosis, Anemia of inadequate production, Anemic pallor, A... ORPHA:86839
Neutropenia, Severe Congenital, 1, Autosomal Dominant
Acute monocytic leukemia, Congenital agranulocytosis, Thrombocytosis, Eosinophilia, Neutropenia, ... OMIM:202700
Combined Oxidative Phosphorylation Deficiency 20
Left ventricular noncompaction, Hypertrophic cardiomyopathy OMIM:615917
Diamond-Blackfan Anemia 20
Erythroid hypoplasia, Anemia, Total anomalous pulmonary venous return OMIM:618313
Glycogen Storage Disease Due To Muscle Phosphofructokinase Deficiency
Anemia, Skeletal muscle atrophy, Increased muscle glycogen content ORPHA:371
Anemia, Hypochromic Microcytic, With Iron Overload 1
Anemia, Erythroid hyperplasia, Decreased mean corpuscular volume, Hypochromia OMIM:206100
Diamond-Blackfan Anemia
Macrocytic dyserythropoietic anemia, Increased mean corpuscular volume, Abnormality of the thenar... ORPHA:124
Retinitis Pigmentosa 51
Pallor OMIM:613464
Monosomy 7 Myelodysplasia And Leukemia Syndrome 2
Increased mean corpuscular volume, Pancytopenia, Acute myeloid leukemia, Thrombocytopenia, Neutro... OMIM:619041
Dohle Bodies And Leukemia
Anemia, Acute myeloid leukemia, Secundum atrial septal defect, Leukocyte inclusion bodies OMIM:223350
Hydrops, Lactic Acidosis, And Sideroblastic Anemia
Increased mean corpuscular volume, Extramedullary hematopoiesis, Sideroblastic anemia, Erythroid ... OMIM:617021
Hyperinsulinism Due To Hnf1A Deficiency
Pallor ORPHA:324575
Diamond-Blackfan Anemia 1
Increased mean corpuscular volume, Persistence of hemoglobin F, Elevated red cell adenosine deami... OMIM:105650
Alpha-Thalassemia
Extramedullary hematopoiesis, Microcytic anemia, Hemoglobin Barts, Hepatosplenomegaly, Hypersplen... ORPHA:846
Pearson Marrow-Pancreas Syndrome
Erythema, Sideroblastic anemia, Pancytopenia, Pallor, Refractory sideroblastic anemia, Reticulocy... OMIM:557000
Fanconi Anemia, Complementation Group E
Abnormal heart morphology, Pancytopenia, Anemia, Reticulocytopenia, Anemic pallor, Neutropenia, T... OMIM:600901
Dravet Syndrome
Pallor ORPHA:33069
Sepsis In Premature Infants
Leukocytosis, Splenomegaly, Pallor, Petechiae, Thrombocytopenia, Neutropenia, Anemia, Purpura ORPHA:90051
Fanconi Anemia, Complementation Group A
Abnormal heart morphology, Pancytopenia, Anemia, Reticulocytopenia, Anemic pallor, Neutropenia, T... OMIM:227650
3-Hydroxy-3-Methylglutaric Aciduria
Dilated cardiomyopathy, Leukopenia, Leukocytosis, Pallor, Thrombocytosis, Anemia ORPHA:20
Fanconi Anemia, Complementation Group C
Pancytopenia, Intrauterine growth retardation, Ventricular septal defect, Anemia, Reticulocytopen... OMIM:227645
Combined Oxidative Phosphorylation Deficiency 42
Anemia, Intrauterine growth retardation, Cardiomyopathy, Neonatal death OMIM:618839
Combined Oxidative Phosphorylation Deficiency 40
Anemia, Intrauterine growth retardation, Hypertrophic cardiomyopathy, Neonatal death OMIM:618835
Irida Syndrome
Pallor ORPHA:209981
Neutrophilic Dermatosis, Acute Febrile
Anemia, Erythema, Dilated cardiomyopathy, Pyoderma gangrenosum OMIM:608068
Non-Functioning Paraganglioma
Pallor ORPHA:94080
Kcnq2-Related Epileptic Encephalopathy
Facial erythema, Pallor ORPHA:439218
Waldenström Macroglobulinemia
Normocytic anemia, Pallor, Splenomegaly, Leukemia, Abnormality of neutrophils, Purpura ORPHA:33226
Attrv122I Amyloidosis
Aortic valve stenosis, Restrictive cardiomyopathy, Hypertrophic cardiomyopathy, Tendon rupture, C... ORPHA:85451
Atrial Standstill
Muscular dystrophy, Skeletal muscle atrophy, Cardiomyopathy, Left ventricular noncompaction, Abno... ORPHA:1344
Mitochondrial Complex Ii Deficiency, Nuclear Type 3
Dilated cardiomyopathy, Left ventricular noncompaction, Patent foramen ovale, Neonatal death, Lef... OMIM:619167
Generalized Juvenile Polyposis/Juvenile Polyposis Coli
Anemia, Anemic pallor ORPHA:329971
Myopathy, Mitochondrial, And Ataxia
Increased variability in muscle fiber diameter, Distal amyotrophy, Pallor OMIM:617675
Retinitis Pigmentosa 75
Pallor OMIM:617023
Idiopathic Hypereosinophilic Syndrome
Dilated cardiomyopathy, Skeletal muscle atrophy, Hepatosplenomegaly, Thrombocytosis, Leukocytosis... ORPHA:3260
3-Hydroxy-3-Methylglutaryl-Coa Lyase Deficiency
Anemia, Pallor OMIM:246450
6-Pyruvoyl-Tetrahydropterin Synthase Deficiency
Pallor ORPHA:13
Cardiomyopathy, Dilated, 1D
Left ventricular noncompaction, Left ventricular hypertrophy, Dilated cardiomyopathy OMIM:601494
Beta-Ketothiolase Deficiency
Leukocytosis, Pallor, Thrombocytosis ORPHA:134
Adenohypophysitis
Pallor, Normochromic anemia ORPHA:95512
Fanconi Anemia, Complementation Group D2
Abnormal heart morphology, Pancytopenia, Anemia, Reticulocytopenia, Anemic pallor, Neutropenia, T... OMIM:227646
Idiopathic Aplastic Anemia
Pancytopenia, Ecchymosis, Reticulocytopenia, Thrombocytopenia, Neutropenia, Anemia ORPHA:88
Congenital Hyperinsulinism Due To Hnf4A Deficiency
Pallor ORPHA:263455
Thrombocytopenia, Anemia, And Myelofibrosis
Anemia, Splenomegaly, Thrombocytopenia, Anisopoikilocytosis OMIM:617441
Fumarase Deficiency
Perimembranous ventricular septal defect, Pallor, Polycythemia OMIM:606812
Amegakaryocytic Thrombocytopenia, Congenital, 2
Aplastic anemia, Pancytopenia, Thrombocytopenia, Neutropenia, Anemia OMIM:620481
Cone-Rod Dystrophy 8
Pallor OMIM:605549
Panhypophysitis
Pallor, Normochromic anemia ORPHA:95513
Tay-Sachs Disease
Pallor OMIM:272800
Non-Functioning Pituitary Adenoma
Pallor, Anemia of inadequate production ORPHA:91349
Pituitary Apoplexy
Pallor, Normochromic anemia ORPHA:95613
Von Hippel-Lindau Disease
Polycythemia, Cardiomyopathy, Upper limb muscle weakness, Pallor, Distal lower limb muscle weakne... ORPHA:892
Sheehan Syndrome
Dry skin, Pallor, Normochromic anemia ORPHA:91355
Degcags Syndrome
Hepatosplenomegaly, Pancytopenia, Leukopenia, Intrauterine growth retardation, Patent foramen ova... OMIM:619488
Methylmalonic Aciduria And Homocystinuria, Cblc Type
Pallor, Thrombocytopenia, Megaloblastic anemia, Neutropenia OMIM:277400
Senior-Loken Syndrome 8
Pallor OMIM:616307
Neuroblastoma
Anemia, Anemic pallor, Thrombocytopenia ORPHA:635
Childhood Absence Epilepsy
Pallor ORPHA:64280
Sick Sinus Syndrome 2
Left ventricular noncompaction, Left ventricular hypertrophy, Mitral valve prolapse OMIM:163800
Fructose-1,6-Bisphosphatase Deficiency
Pallor ORPHA:348
Alternating Hemiplegia Of Childhood
Facial hypotonia, Pallor, Cardiomyopathy ORPHA:2131
Sporadic Pheochromocytoma/Secreting Paraganglioma
Pallor ORPHA:276621
Infection-Related Hemolytic Uremic Syndrome
Pallor, Leukocytosis, Thrombocytopenia, Myocarditis, Hemolytic anemia ORPHA:544482
Incontinentia Pigmenti
Erythema, Eosinophilia, Leukocytosis, Pallor OMIM:308300
Autosomal Recessive Malignant Osteopetrosis
Anemia, Abnormal pulmonary valve morphology, Splenomegaly, Pallor ORPHA:667
Naxos Disease
Dilated cardiomyopathy, Abnormal heart morphology, Right ventricular cardiomyopathy, Cardiomegaly... OMIM:601214
Cardiomyopathy, Dilated, 1S
Dilated cardiomyopathy, Left ventricular noncompaction, Interstitial cardiac fibrosis, Bicuspid a... OMIM:613426
Histiocytoid Cardiomyopathy
Cardiomegaly, Pallor, Ventricular septal defect ORPHA:137675
Long Qt Syndrome 15
Left ventricular noncompaction OMIM:616249
Hereditary Pheochromocytoma-Paraganglioma
Pallor ORPHA:29072
Prolactinoma
Pallor ORPHA:2965
Congenital Total Pulmonary Venous Return Anomaly
Hypoplastic left heart, Mixed total anomalous pulmonary venous connection, Atrial situs ambiguous... ORPHA:99125
Esophageal Atresia
Tetralogy of Fallot, Pallor, Ventricular septal defect ORPHA:1199
Tsh-Secreting Pituitary Adenoma
Pericardial effusion, Pallor ORPHA:91347
Multiple Endocrine Neoplasia Type 2
Proximal amyotrophy, Pallor ORPHA:653
Intellectual Developmental Disorder, X-Linked, Syndromic 34
Left ventricular noncompaction, Left ventricular noncompaction cardiomyopathy, Patent foramen ova... OMIM:300967
Muscular Dystrophy-Dystroglycanopathy (Congenital With Brain And Eye Anomalies), Type A, 3
Muscular dystrophy, Pallor OMIM:253280
Goodpasture Syndrome
Anemia, Pallor OMIM:233450
Homozygous Familial Hypercholesterolemia
Myocardial steatosis, Tendon xanthomatosis, Abnormal tendon morphology ORPHA:391665
Familial Cerebral Cavernous Malformation
ORPHA:221061
Cerebral Cavernous Malformations 3
OMIM:603285

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Pdcd10

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Pdcd10.

No publications found that use IMPC mice or data for Pdcd10.

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MGI Allele Allele Type Produced
Pdcd10tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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