Gene: Sirt3

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Phenotype System Allele Zyg Sex Life Stage P Value
vertebral fusion Sirt3tm1b(EUCOMM)Wtsi HOM   Early adult 8.11×10-07
abnormal gait Sirt3tm1b(EUCOMM)Wtsi HOM Early adult 1.16×10-06
increased circulating creatine kinase level Sirt3tm1b(EUCOMM)Wtsi HOM Early adult 1.73×10-07
increased circulating alanine transaminase level Sirt3tm1b(EUCOMM)Wtsi HOM Early adult 7.21×10-06

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Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
6 No  (4/584)  (4/6)  Wholemount images
6 No  (1/584)  (3/6)  Wholemount images
6 No N/A
6 No  (4/584)  (4/6)  Wholemount images
6 No  (2/584)  (4/6)  Wholemount images
6 No  (4/6)  Wholemount images
6 No  (1/584)  (4/6)  Wholemount images
6 No  (3/584)  (4/6)  Wholemount images
6 No  (2/584)  (4/6)  Wholemount images
6 No  (7/408) N/A
6 No N/A
6 No  (4/6)  Wholemount images
6 No  (2/584)  (4/6)  Wholemount images
6 No  (3/584)  (4/6)  Wholemount images
6 No  (2/584)  (4/6)  Wholemount images
6 No  (21/584)  (4/6)  Wholemount images
6 No  (10/584)  (1/6) N/A
6 No  (4/6)  Wholemount images
6 No  (1/584)  (3/6)  Wholemount images
6 No  (2/584)  (3/6)  Wholemount images
6 No  (1/584) N/A
6 No N/A
6 No  (2/584)  (4/6)  Wholemount images
6 No N/A
6 No  (1/584) N/A
6 No  (3/6)  Wholemount images
6 No  (5/584) N/A
6 No  (1/562)  (4/6)  Wholemount images
6 No  (2/584)  (3/6)  Wholemount images
6 No N/A
6 No  (1/584)  (4/6)  Wholemount images
6 No  (12/584) N/A
6 No N/A
6 No  (1/584) N/A
6 No  (9/584) N/A
6 No  (3/584)  (4/6)  Wholemount images
6 No  (3/584) N/A
6 No  (12/584)  (4/6)  Wholemount images
6 No  (3/584)  (4/6)  Wholemount images
6 No  (6/584)  (2/6)  Wholemount images
6 No  (1/584) N/A
6 No  (16/584)  (4/6)  Wholemount images
6 No  (3/584)  (4/6)  Wholemount images
6 No  (3/6)  Wholemount images
6 No N/A
6 No N/A
No Embryo expression data was found for this gene.

 Associated Images

X-ray: XRay Images Whole Body Lateral Orientation
30 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
30 Images
X-ray: XRay Images Skull Lateral Orientation
14 Images
X-ray: XRay Images Forepaw
9 Images
X-ray: XRay Images Whole Body Dorso Ventral
30 Images
Echo: M-Mode Images
36 Images
Adult LacZ: LacZ Images Wholemount
17 Images
Legacy Phenotype Associated Images

View all 105 images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Histopathology

 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Sirt3tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells
Sirt3tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Sirt3tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Sirt3tm47264(L1L2_gt1) Targeting vectors

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