Gene: Sirt3

Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal gait Sirt3tm1b(EUCOMM)Wtsi HOM postnatal 1.58×10-06
vertebral fusion Sirt3tm1b(EUCOMM)Wtsi HOM postnatal 1.31×10-06

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Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 6 No  (2/584)  (4/6)  Wholemount images
Aorta 6 No  (3/6)  Wholemount images
Bone 6 No N/A
Brain 6 No  (4/6)  Wholemount images
Brainstem 6 No  (4/6)  Wholemount images
Brown adipose tissue 6 No  (4/6)  Wholemount images
Cartilage tissue 6 No  (4/6)  Wholemount images
Cerebellum 6 No  (4/6)  Wholemount images
Cerebral cortex 6 No  (4/6)  Wholemount images
Esophagus 6 No  (7/415) N/A
Eye 6 No N/A
Gall bladder 6 No  (4/6)  Wholemount images
Heart 6 No  (4/6)  Wholemount images
Hippocampus 6 No  (4/6)  Wholemount images
Hypothalamus 6 No  (4/6)  Wholemount images
Kidney 6 No  (18/584)  (4/6)  Wholemount images
Large intestine 6 No  (10/584)  (1/6) N/A
Liver 6 No  (4/6)  Wholemount images
Lower urinary tract 6 No  (3/6)  Wholemount images
Lung 6 No  (3/6)  Wholemount images
Lymph node 6 No N/A
Mammary gland 6 No N/A
Olfactory lobe 6 No  (4/6)  Wholemount images
Oral epithelium 6 No N/A
Ovary 6 No  (1/584) N/A
Oviduct 6 No  (3/6)  Wholemount images
Pancreas 6 No  (5/584) N/A
Parathyroid gland 6 No  (4/6)  Wholemount images
Peripheral nervous system 6 No  (3/6)  Wholemount images
Peyer's patch 6 No N/A
Pituitary gland 6 No  (4/6)  Wholemount images
Prostate gland 6 No  (12/584) N/A
Skeletal muscle 6 No N/A
Skin 6 No N/A
Small intestine 6 No  (9/584) N/A
Spinal cord 6 No  (4/6)  Wholemount images
Spleen 6 No  (2/584) N/A
Stomach 6 No  (12/584)  (4/6)  Wholemount images
Striatum 6 No  (4/6)  Wholemount images
Testis 6 No  (2/584)  (2/6)  Wholemount images
Thymus 6 No N/A
Thyroid gland 6 No  (15/584)  (4/6)  Wholemount images
Trachea 6 No  (4/6)  Wholemount images
Uterus 6 No  (3/6)  Wholemount images
Vascular system 6 No N/A
White adipose tissue 6 No N/A
No Embryo expression data was found for this gene.

 Associated Images

Echo: M-Mode Images
36 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
30 Images
X-ray: XRay Images Dorso Ventral
53 Images
X-ray: XRay Images Lateral Orientation
44 Images
X-ray: XRay Images Skull Lateral Orientation
14 Images
X-ray: XRay Images Forepaw
9 Images
Adult LacZ: LacZ Images Wholemount
17 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Sirt3tm47264(L1L2_gt1) Targeting vectors
Sirt3tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Sirt3tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Sirt3tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells

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